NCAPD3

NCAPD3
Identifiers
Aliases	NCAPD3 , CAP-D3, CAPD3, hCAP-D3, hHCP-6, hcp-6, non-SMC condensin II complex subunit D3, MCPH22
External IDs	OMIM: 609276 MGI: 2142989 HomoloGene: 41021 GeneCards: NCAPD3
Gene location (Human)
Chr.	Chromosome 11 (human)
End	134,225,504 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	27,006,611 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; secondary oocyte; ; prostate; ; ganglionic eminence; ; stromal cell of endometrium; ; right lobe of liver; ; bone marrow cells; ; skin of abdomen; ; anterior pituitary; ; left lobe of thyroid gland;
	Top expressed in
	hand; ; Paneth cell; ; thymus; ; dermis; ; superior cervical ganglion; ; abdominal wall; ; vas deferens; ; bone marrow; ; primitive streak; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methylated histone binding ; chromatin binding ; protein binding ; histone binding ;
Cellular component	membrane ; nucleus ; condensed chromosome, centromeric region ; nucleoplasm ;
Biological process	mitotic chromosome condensation ; chromosome separation ; cell division ; cell cycle ; chromosome condensation ; meiotic chromosome condensation ;
	Sources:Amigo / QuickGO
Orthologs
	23310
	78658
	ENSG00000151503
	ENSMUSG00000035024
	P42695
	Q6ZQK0
	NM_015261 ; NM_001372065 ; NM_001372068 ; NM_001372069 ; NM_001372070
	NM_178113 ; NM_001382847
	NP_056076 ; NP_001358994 ; NP_001358997 ; NP_001358998 ; NP_001358999
	NP_835214 ; NP_001369776
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the NCAPD3 gene.^[5]^[6]^[7]^[8] CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

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Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded by the SMC4 gene. SMC-4 is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation.

Condensin complex subunit 1 also known as chromosome-associated protein D2 (CAP-D2) or non-SMC condensin I complex subunit D2 (NCAPD2) or XCAP-D2 homolog is a protein that in humans is encoded by the NCAPD2 gene. CAP-D2 is a subunit of condensin I, a large protein complex involved in chromosome condensation.

MORC family CW-type zinc finger protein 2 is a protein that in humans is encoded by the MORC2 gene.

Condensin complex subunit 2 also known as chromosome-associated protein H (CAP-H) or non-SMC condensin I complex subunit H (NCAPH) is a protein that in humans is encoded by the NCAPH gene. CAP-H is a subunit of condensin I, a large protein complex involved in chromosome condensation

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene. CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

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Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene. CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation. It interacts with PLK1 through its C-terminal region during mitosis

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Condensin-2 complex subunit H2, also known as chromosome-associated protein H2 (CAP-H2) or non-SMC condensin II complex subunit H2 (NCAPH2), is a protein that in humans is encoded by the NCAPH2 gene. CAP-H2 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000151503 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035024 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (December 1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research . 1 (5): 223–229. doi: 10.1093/dnares/1.5.223 . PMID 7584044.
↑ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (June 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry . 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
↑ Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (October 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell . 115 (1): 109–121. doi: 10.1016/S0092-8674(03)00724-4 . PMID 14532007. S2CID 18811084.
↑ "NCAPD3 non-SMC condensin II complex, subunit D3". National Center for Biotechnology Information . Retrieved June 10, 2012.

Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC 1459365 . PMID 16565220.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000151503 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035024 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7584044-5] Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (December 1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research . 1 (5): 223–229. doi: 10.1093/dnares/1.5.223 . PMID 7584044.

[pmid8619474-6] Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (June 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry . 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.

[pmid14532007-7] Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (October 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell . 115 (1): 109–121. doi: 10.1016/S0092-8674(03)00724-4 . PMID 14532007. S2CID 18811084.

[entrez-8] "NCAPD3 non-SMC condensin II complex, subunit D3". National Center for Biotechnology Information . Retrieved June 10, 2012.

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NCAPD3

Related Research Articles

References

Further reading