Phycoerythrobilin synthase

Phycoerythrobilin synthase
Identifiers
EC no.	1.3.7.6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Phycoerythrobilin synthase (EC 1.3.7.6, PebS) is an enzyme with systematic name (3Z)-phycoerythrobilin:ferredoxin oxidoreductase (from biliverdin IX alpha). ^[1] It catalyses the following chemical reaction

biliverdin

+ 2 reduced
ferredoxin

 

 

 

 

 

 

 

(3Z)-phycoerythrobilin

+ 2 oxidised
ferredoxin

 

This enzyme, from a cyanophage infecting oceanic cyanobacteria of the Prochlorococcus genus carries out in one step the reduction of biliverdin to (3Z)-phycoerythrobilin. The same overall reaction results from the action of 15,16-dihydrobiliverdin:ferredoxin oxidoreductase and phycoerythrobilin:ferredoxin oxidoreductase in oxygenic organisms. ^{[2] [3]}

References

1. Dammeyer T, Bagby SC, Sullivan MB, Chisholm SW, Frankenberg-Dinkel N (March 2008). "Efficient phage-mediated pigment biosynthesis in oceanic cyanobacteria". Current Biology. 18 (6): 442–8. Bibcode:2008CBio...18..442D. doi: 10.1016/j.cub.2008.02.067 . PMID   18356052.
2. Enzyme 1.3.7.6 at KEGG Pathway Database.
3. Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC (2001). "Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms". Plant Cell. 13 (4): 965–78. Bibcode:2001PlanC..13..965F. doi:10.1105/tpc.13.4.965. PMC   135530 . PMID   11283349.

External links

• Phycoerythrobilin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)