Popliteal artery aneurysm

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Popliteal artery aneurysm
Specialty Vascular surgery, interventional radiology
Symptoms None, painful and cold legs
Risk factors Smoking, hypertension, other cardiovascular disease, family history, Marfan syndrome
PreventionNot smoking, treating risk factors
TreatmentSurgery (open surgery or endovascular aneurysm repair)

A popliteal artery aneurysm (PAA) is an enlargement (aneurysm) of the popliteal artery to greater than 1.5 times its normal size. [a] PAAs are the most common type of aneurysm of the peripheral vascular system, accounting for 85% of all cases. Roughly half of all popliteal aneurysms appear on both legs, being associated with an abdominal aortic aneurysm 40–50% of the time. [1]

Contents

Popliteal aneurysms very rarely cause symptoms; they are typically discovered during routine physical examinations. The cause of these aneurysms is unknown, but they are more common in older people and men. [2] Elective surgery is usually recommended for aneurysms over 20 mm in size.

Signs and symptoms

PAAs are most often asymptomatic. [1] Chronic symptoms are most often caused by the mass effect resulting from the compression of nearby structures, such as pain and paresthesia due to tibial nerve compression and calf swelling due to compression of the popliteal vein. [1]

Thrombosis within the aneurysm and subsequent luminal narrowing may result in claudication (pain while walking) of gradual onset. An acute thrombosis, completely obstructing blood flow at the side of the aneurysm or lodging distally as the vessel narrows, may lead to acute limb ischaemia and associated symptoms such as local pain, paresthesia, paleness, weakness, and inability to maintain temperature). Thrombotic occlusion of distal vessels may result in blue toe syndrome, and acrocyanosis. Untreated, some 30% of those affected develop acute thrombosis and distal embolization, risking potential limb loss. In cases with acute thrombosis/embolism, amputation rate is 15%. [1]

Causes

Although the exact causes behind popliteal aneurysms remain unknown and under speculation, several risk factors are known to predispose the development of a PAA, including: tobacco smoking, atherosclerosis, connective tissue disorders (such as Marfan syndrome or Ehlers-Danlos syndrome), advanced age (peaking in the 6th to 7th decade of life), male gender, White race, and a family history of aneurysm. [1]

Diagnosis

The popliteal fossa is to be examined bilaterally (on both sides) with the knee in a semi-flexed position. In some 60% of cases, the popliteal aneurysm presents as a palpable pulsatile mass at the level of the knee. Doppler ultrasonography is the preferred diagnostic method. CT angiography and MR angiography may also be employed. [1]

Differential diagnosis

Differential diagnoses include: popliteal cysts, adventitial cysts, [3] [1] lymphadenopathy, and varicose veins. [1]

Management

The Society for Vascular Surgery recommends elective surgery for asymptomatic PAAs of at least 20 mm in diameter; there is weaker evidence for waiting until a size of 30 mm for patients with higher surgical risk. Screening for both a PAA on the other leg and for an abdominal aortic aneurysm is considered essential. [4]

A 2019 systematic review was unsure whether endovascular aneurysm repair or open surgery is better for those with aneurysms that are not causing symptoms. Stenting, however, was associated with shorter hospital stays and operating times with moderate-certainty evidence. [5]

Prognosis

A PAA rarely presents with a size greater than 5 cm, as symptoms typically develop before the aneurysm reaches such a size. Unlike aneurysms elsewhere in the body, the typical course of PAAs is to embolize and produce ischaemia, rather than to progress to rupture. [3]

Notes

  1. The normal diameter of a popliteal artery is 0.7–1.1 cm. [1]

References

  1. 1 2 3 4 5 6 7 8 9 Kassem, Mohammed M.; Gonzalez, Lorena (2020), "Popliteal Artery Aneurysm", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID   28613613 , retrieved 18 September 2020
  2. "Popliteal Artery Aneurysm". Vasculardoc.com. Retrieved 5 October 2014.
  3. 1 2 Drake, Richard L. (Richard Lee), 1950- (15 November 2015). Gray's anatomy for students. Vogl, Wayne,, Mitchell, Adam W. M.,, Gray, Henry, 1825-1861. (Third ed.). Philadelphia, PA. p. 679. ISBN   978-0-7020-5131-9. OCLC   881508489.{{cite book}}: CS1 maint: location missing publisher (link) CS1 maint: multiple names: authors list (link) CS1 maint: numeric names: authors list (link)
  4. Farber, Alik; Angle, Niren; Avgerinos, Efthymios; Dubois, Luc; Eslami, Mohammad; Geraghty, Patrick; Haurani, Mounir; Jim, Jeffrey; Ketteler, Erika; Pulli, Raffaele; Siracuse, Jeffrey J.; Murad, M. Hassan (2022). "The Society for Vascular Surgery clinical practice guidelines on popliteal artery aneurysms". Journal of Vascular Surgery. 75 (1). Elsevier BV: 109S –120S. doi: 10.1016/j.jvs.2021.04.040 . ISSN   0741-5214.
  5. Joshi, Dhiraj; Gupta, Yuri; Ganai, Bhaskar; Mortensen, Chloe (23 December 2019). "Endovascular versus open repair of asymptomatic popliteal artery aneurysm". The Cochrane Database of Systematic Reviews. 2019 (12) CD010149. doi:10.1002/14651858.CD010149.pub3. ISSN   1469-493X. PMC   6927522 . PMID   31868929.