Pseudobaptigenin synthase

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Pseudobaptigenin synthase
Identifiers
EC no. 1.14.21.8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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NCBI proteins

Pseudobaptigenin synthase (EC 1.14.21.8) is an enzyme with systematic name calycosin,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming). [1] This enzyme catalyses the following chemical reaction

(1) calycosin + NADPH + H+ + O2 pseudobaptigenin + NADP+ + 2 H2O
(2) pratensein + NADPH + H+ + O2 5-hydroxypseudobaptigenin + NADP+ + 2 H2O

Pseudobaptigenin synthase is a heme-thiolate enzyme (P450) that catalyses a step in the biosynthesis of (-)-maackiain.

References

  1. Clemens S, Barz W (1996). "Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum". Phytochemistry. 41 (2): 457–460. Bibcode:1996PChem..41..457C. doi:10.1016/0031-9422(95)00618-4.