SNX3

Last updated
SNX3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SNX3 , Grd19, MCOPS8, SDP3, sorting nexin 3
External IDs OMIM: 605930; MGI: 1860188; HomoloGene: 36144; GeneCards: SNX3; OMA:SNX3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152828
NM_001300928
NM_001300929
NM_003795
NM_152827

NM_017472

RefSeq (protein)

NP_001287857
NP_001287858
NP_003786
NP_690040

n/a

Location (UCSC) Chr 6: 108.21 – 108.26 Mb Chr 10: 42.38 – 42.41 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Sorting nexin-3 is a protein that in humans is encoded by the SNX3 gene. [5] [6]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000112335 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019804 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Haft CR, de la Luz Sierra M, Barr VA, Haft DH, Taylor SI (Dec 1998). "Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors". Mol Cell Biol. 18 (12): 7278–87. doi:10.1128/mcb.18.12.7278. PMC   109309 . PMID   9819414.
  6. 1 2 "Entrez Gene: SNX3 sorting nexin 3".

Further reading