Spheroidene monooxygenase

Spheroidene monooxygenase
Identifiers
EC no.	1.14.15.9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Spheroidene monooxygenase (EC 1.14.15.9, CrtA, acyclic carotenoid 2-ketolase, spirilloxantin monooxygenase, 2-oxo-spirilloxanthin monooxygenase) is an enzyme with systematic name spheroidene, reduced-ferredoxin:oxygen oxidoreductase (spheroiden-2-one-forming). ^{[1] [2]} This enzyme catalyses the following chemical reaction

spheroidene + reduced ferredoxin + O₂${\displaystyle \rightleftharpoons }$ spheroiden-2-one + oxidized ferredoxin + H₂O

spirilloxantin + reduced ferredoxin + O₂${\displaystyle \rightleftharpoons }$ 2-oxospirilloxanthin + oxidized ferredoxin + H₂O

2'-oxospirilloxanthin + reduced ferredoxin + O₂${\displaystyle \rightleftharpoons }$ 2,2'-dioxospirilloxanthin + oxidized ferredoxin + H₂O

The enzyme is involved in spheroidenone biosynthesis and in 2,2'-dioxospirilloxanthin biosynthesis.

References

1. Lee PC, Holtzapple E, Schmidt-Dannert C (November 2010). "Novel activity of Rhodobacter sphaeroides spheroidene monooxygenase CrtA expressed in Escherichia coli". Applied and Environmental Microbiology. 76 (21): 7328–31. doi:10.1128/AEM.01606-10. PMC   2976243 . PMID   20851979.
2. Gerjets T, Steiger S, Sandmann G (February 2009). "Catalytic properties of the expressed acyclic carotenoid 2-ketolases from Rhodobacter capsulatus and Rubrivivax gelatinosus". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1791 (2): 125–31. doi:10.1016/j.bbalip.2008.12.006. PMID   19136077.

External links

• Spheroidene+monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)