U.S. Route 67 is a major north–south U.S. highway which extends for 1,560 miles (2,511 km) in the Central United States. The southern terminus of the route is at the United States-Mexico border in Presidio, Texas, where it continues south as Mexican Federal Highway 16 upon crossing the Rio Grande. The northern terminus is at U.S. Route 52 in Sabula, Iowa. US 67 crosses the Mississippi River twice along its routing. The first crossing is at West Alton, Missouri, where US 67 uses the Clark Bridge to reach Alton, Illinois. About 240 miles (390 km) to the north, US 67 crosses the river again at the Rock Island Centennial Bridge between Rock Island, Illinois, and Davenport, Iowa. Additionally, the route crosses the Missouri River via the Lewis Bridge a few miles southwest of the Clark Bridge.
U.S. Route 183 (US 183) is a north–south United States highway. The highway's northern terminus is in Presho, South Dakota, at an intersection with Interstate 90. Its southern terminus is in Refugio, Texas, at the southern intersection of U.S. Highway 77 and Alternate US 77.
U.S. Route 259 is a north–south spur of U.S. Route 59 that runs for 250 miles (400 km) through rural areas of northeastern Texas and southeastern Oklahoma. The highway's southern terminus is near Nacogdoches, Texas, at an interchange with its parent route, US 59. Its northern terminus is in the Ouachita Mountains, approximately 15 miles (24 km) south of Heavener, Oklahoma, where it reunites with US 59. For most of its length, US 259 lies 30–50 miles (48–80 km) to the west of its parent route.
U.S. Route 277 is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route, US 77, although it does intersect another one of its spur. It runs for 633 miles (1,019 km) across Oklahoma and Texas. US 277's northern terminus is in Newcastle, Oklahoma at Interstate 44, which is also the northern terminus of the H.E. Bailey Turnpike. Its southern terminus is in Carrizo Springs, Texas at U.S. Route 83. It passes through the states of Oklahoma and Texas.
U.S. Route 283 is a spur of U.S. Route 83. It currently runs for 731 miles (1,175 km) from Brady, Texas at U.S. Route 87 to Lexington, Nebraska at U.S. Route 30. It passes through the states of Texas, Oklahoma, Kansas, and Nebraska.
U.S. Route 385 (US 385) is a spur of U.S. Route 85 that runs for 1,206 miles (1,941 km) from Deadwood, South Dakota to Big Bend National Park in Texas.
State Highway 18 is a state highway in the U.S. state of Texas maintained by the Texas Department of Transportation (TxDOT) that runs from Fort Stockton in western Texas to the New Mexico state line between Kermit and Jal, New Mexico. This route was designated in 1958 over the northern half of what was previously SH 82.
In the US state of Texas, Interstate 40 (I-40) runs west–east through the panhandle in the northwest part of the state. The only large city it passes through is Amarillo, where it meets the north end of I-27. The entire section of I-40 in Texas is designated as a Purple Heart Trail route.
State Highway 158 is a state highway running from near Goldsmith, Texas eastward to Ballinger, Texas.
Interstate 20 in Texas (I-20) is a major east–west Interstate Highway in the Southern United States, running east from a junction with I-10 east of Kent, Texas, through the Dallas–Fort Worth metroplex to the Louisiana state line near Waskom, Texas. The original distance of I-20 was 647 miles (1,041 km) from I-10 to the Louisiana state line, reduced to the current distance of 636 miles (1,024 km) with the rerouting of I-20 in the 1980s and 1990s. I-20 is known as the Ronald Reagan Memorial Highway within the Dallas–Fort Worth metroplex.
U.S. Highway 287 (US 287) in the U.S. state of Texas is a major U.S. Highway that begins on the Gulf Coast in Port Arthur and heads north through Fort Worth, northwest to Childress, Clarendon, Wichita Falls, and Amarillo in the Texas Panhandle and into Oklahoma near Kerrick.
U.S. Route 62 is a US highway that runs from the Mexico–US border at El Paso, TX to the Canada-US border at Niagara Falls, NY. In Texas, the highway exists in two segments separated by a segment in New Mexico. US 62 is a major corridor in West Texas as it connects the cities of El Paso and Lubbock.
U.S. Route 67 is a major U.S. highway in the state of Texas. It runs from the U.S.–Mexico border west of Presidio to Texarkana at the Arkansas state line. US 67 is part of the La Entrada al Pacifico international trade corridor from its southern terminus to US 385 in McCamey.
U.S. Route 77 (US 77) is a major highway that is part of the United States Numbered Highway System that runs from the Veterans International Bridge in Brownsville to Sioux City, Iowa. In Texas, the road runs south-north for 471.3 miles (758.5 km) from the International border with Mexico to the Oklahoma state line north of Gainesville. The highway is being upgraded to a freeway near Corpus Christi to connect to the freeway part of the highway in Raymondville as part of future I-69. A freeway in Robstown is already signed as part of I-69. From Waco to the Oklahoma state line, US 77 overlaps or runs parallel to I-35/I-35E.
U.S. Route 79 is a U.S. highway that begins in the state of Texas at Interstate 35 in Round Rock. The highway travels northeast–southwest through the state, crossing into Louisiana approximately 23 miles northeast of Carthage. US 79 is entwined with two tragedies of country music: Johnny Horton was killed by a drunk driver on the highway near Milano in 1960 and Jim Reeves, killed in a plane crash in 1964, is buried and memorialized on US 79 in his hometown of Carthage.
U.S. Route 84 is a U.S. highway that runs from Pagosa Springs, CO to Midway, GA. In Texas, the highway enters the state from New Mexico at Farwell, near the Panhandle region. Major cities along the highway include Lubbock, Abilene, Waco and Palestine. The highway exits Texas into Louisiana near Joaquin, crossing the Toledo Bend Reservoir.
U.S. Route 80 is a U.S. highway that begins in the state of Texas in Dallas at an interchange with I-30. US 80 runs in an east–west direction for most of its length from Dallas to Louisiana. Before the advent of the Interstate Highway System, US 80 through Texas was once a vital link in a major transcontinental highway with the national western terminus being in San Diego, California rather than Dallas. Since 1991, most of US 80 in Texas has been decommissioned in favor of I-10, I-20 and I-30 between the New Mexico state line and its current western terminus.
U.S. Highway 285 (US 285) travels from Sanderson, Texas to Denver, Colorado. In Texas, US 285 begins at an intersection with US 90 in Sanderson, traveling through Fort Stockton and Pecos before exiting the state into New Mexico between Pecos and Carlsbad.
All of the business loops within Texas are maintained by the Texas Department of Transportation (TxDOT). Interstate 20 (I-20) has 15 business loops in the state, all located in western Texas. Along I-20, TxDOT identifies each business route as Business Interstate 20 followed by an alphabetic suffix. Along Texas Interstates, the alphabetic suffixes on business route names ascend eastward and northward. There are gaps in the alphabetic values to allow for future system expansion. The alphabetic naming suffixes are included as small letters on the bottom of route shields.
Interstate business routes are roads connecting a central or commercial district of a city or town with an Interstate bypass. These roads typically follow along local streets often along a former U.S. Route or state highway that had been replaced by an Interstate. Interstate business route reassurance markers are signed as either loops or spurs using a green shield shaped and numbered like the shield of the parent Interstate highway.
Big Bend National Park 
US 385 at Oklahoma state line
