5 May – Perpetual Maritime Truce comes into force between the United Kingdom and the rulers of the Sheikhdoms of the Lower Gulf, later known as the Trucial States.[6]
1 July – first constitution of the Cape Colony provides for a legislative council.[7]
1 August – under terms of the Vaccination Act 1853, all children born after this date are to receive compulsory vaccination against smallpox during their first 3 months of life, with defaulting parents subject to a fine.[8]
12 August – Licensing (Scotland) Act (known after its sponsor as the 'Forbes Mackenzie Act') regulates the supply of intoxicating beverages in Scotland.[9]
20 August – Penal Servitude Act provides for convicted criminals to serve their entire sentence in prison, rather than suffer transportation, and also to be freed on licence.[10]
28 September – emigrant ship Annie Jane sinks in heavy seas off the Scottish island of Vatersay with the loss of 350 lives.[13]
31 October–15 May 1854 – lockout of Prestoncotton mill workers seeking reinstatement of ten per cent of their pay; this will be Britain's longest industrial dispute up to this date.[14]
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