The 2018 Columbus Crew SC season was the club's twenty-third season of existence, and their twenty-third consecutive season in Major League Soccer, the top flight of American soccer. Columbus also competed in the U.S. Open Cup, and took part in the Pacific Rim Cup and Carolina Challenge Cup during preseason. The season covered the period from November 30, 2017, to the start of the 2019 Major League Soccer season.
The 2020 Columbus Crew SC season was the club's twenty-fifth season of existence and their twenty-fifth consecutive season in Major League Soccer, the top flight of American soccer. Columbus were also set to compete in the U.S. Open Cup, before its cancelation due to the COVID-19 pandemic. The season covers the period from November 11, 2019 to the start of the 2021 Major League Soccer season.
The 2020 Orlando City SC season was the club's 10th season of existence in Orlando and sixth season as a Major League Soccer franchise, the top-flight league in the United States soccer league system. Due to the COVID-19 pandemic, the U.S. Open Cup was canceled.
The 2020 Nashville SC season was the club's first season as an organization and its first season as a member of Major League Soccer, after two seasons in the Eastern Conference of the USL Championship by a club of the same name.
The 2020 New York City FC season was the club's sixth season of competition and its sixth in the top tier of American soccer, Major League Soccer. New York City FC usually played its home games at Yankee Stadium in the New York City borough of The Bronx. However, the 2020 MLS season saw the club play several of their home games at Red Bull Arena in Harrison, New Jersey due to scheduling conflicts at both Yankee Stadium and Citi Field as well as winterization procedures during the 2020 CONCACAF Champions League which were unavoidable.
The 2021 D.C. United season was the club's 26th season of existence, and their 26th consecutive season playing in Major League Soccer, the top flight of American soccer. Due to the COVID-19 pandemic and its ongoing vaccination efforts, the season began on April 17, 2021 and ended on November 7, 2021. Despite winning against Toronto FC on the last match of the regular season, the team did not qualify playoffs, making it their second consecutive season in which D.C. United did not qualify for the playoffs. It was the first time since 2011, that United did not qualify for the playoffs in consecutive seasons.
The 2021 FC Cincinnati season was the club's third season in MLS, and the sixth season of a team playing under the FC Cincinnati brand after three years in the lower-division USL Championship. The club finished with a league worst 4–15–4 record in their second MLS season in 2020, one shortened by the COVID-19 pandemic in Ohio. The season was the first year that FC Cincinnati played home matches at newly built TQL Stadium.
The 2021 Inter Miami CF season was the second season in the history of Inter Miami CF and the 18th season of first-division club soccer in South Florida. In addition to playing in Major League Soccer, the club was scheduled to participate in the U.S. Open Cup but the competition was cancelled for the second consecutive year due to the COVID-19 pandemic.
The 2021 Club de Foot Montréal season was the club's 28th season of existence, and their tenth in Major League Soccer, the top tier of the American soccer pyramid. This was the first season under the club's new name, being known as the Montreal Impact up until this point.
The 2021 LA Galaxy season was the club's 26th season of existence, and their 26th in Major League Soccer, the top-tier of the American soccer pyramid. LA Galaxy played its home matches at the stadium Dignity Health Sports Park in the LA suburb of Carson, California. The Galaxy attempted to make the playoffs after failing to qualify in 2020, but were ultimately unsuccessful.
The 2021 Columbus Crew season was the club's twenty-sixth season of existence and their twenty-sixth consecutive season in Major League Soccer, the top flight of American soccer. The season covers the period from December 13, 2020, to November 7, 2021. It is the third season under head coach Caleb Porter.
The 2021 Philadelphia Union season was the club's twelfth season in Major League Soccer, the top flight of American soccer. The team is managed by Jim Curtin, his eighth season with the club. The club's regular season began on April 7, 2021, with the CONCACAF Champions League, and then on April 17, 2021, with MLS play, and ended on November 7, 2021, a month-delayed start due to the COVID-19 pandemic. Outside of MLS, the Union, by winning the 2020 Supporters' Shield, is competing in their first ever CONCACAF Champions League.
The 2022 FC Cincinnati season was the club's fourth season in MLS, and the seventh season playing under the FC Cincinnati brand after three years in the lower-division USL Championship. FC Cincinnati home matches were played at TQL Stadium.
The 2022 Columbus Crew season was the club's twenty-seventh season of existence and their twenty-seventh consecutive season in Major League Soccer, the top flight of American soccer. The season covered the period from November 8, 2021 to the end of the 2022 season. It was the fourth and final season under head coach Caleb Porter.
The 2022 Inter Miami CF season was the third season in the history of Inter Miami CF and the 19th season of first-division club soccer in South Florida. In addition to playing in Major League Soccer, the club participated in the U.S. Open Cup, the first cup competition in club history.
The 2023 FC Cincinnati season was the club's fifth season in MLS, and the eighth season overall for the team including their first three years in the lower-division USL Championship. The club entered 2023 on a high note, having notched their first playoff appearance and first playoff win in 2022 after languishing at the bottom of the standings for their first three seasons in MLS. On September 30, FC Cincinnati clinched the Supporters' Shield, the award given to the team that finishes with the most points in the regular season.
The 2023 Columbus Crew season was the club's twenty-eighth season of existence and their twenty-eighth consecutive season in Major League Soccer, the top flight of soccer in the United States. The first match of the season was on February 25 against the Philadelphia Union. It was the first season under head coach Wilfried Nancy.
The 2024 Columbus Crew season was the club's twenty-ninth season of existence and their twenty-ninth consecutive season in Major League Soccer, the top flight of soccer in the United States. It was their second season under head coach Wilfried Nancy. The Crew are defending MLS Cup champions, having won the 2023 MLS Cup against Los Angeles FC. On December 20, 2023, MLS released its schedule, with Columbus playing its opening match of the season against Atlanta United FC at home on February 24.
The 2025 CF Montréal season will be the club's 32nd season of existence, and their 14th in Major League Soccer, the top tier of the American soccer pyramid.
The 2025 season will be the 10th season for FC Cincinnati and their 7th in Major League Soccer (MLS), the highest level of men's professional soccer in the United States. Their home stadium is TQL Stadium. It is the fourth season with the club for general manager Chris Albright and head coach Pat Noonan.