The Eastern Conference is one of Major League Soccer's two conferences, along with the Western Conference. The division of the conferences broadly follows the path of the Mississippi River from the Great Lakes to the Gulf of Mexico, with clubs east of the river in the Eastern Conference.
The 2021 Nashville SC season was the club's second season as a member of Major League Soccer. This was the club's last season in the Eastern Conference after being added to the Conference in 2020 after the MLS is Back Tournament as the club returns to the Western Conference the following season in 2022 due to the addition of Charlotte FC.
The 2021 season was the 26th in the history of the Major League Soccer club New England Revolution, a professional soccer team based in Foxborough, Massachusetts. The team was under the management of Bruce Arena in his second full MLS season as head coach of the Revs. The regular season began on April 17, 2021. In addition to the league, the Revolution were to compete in the 2021 U.S. Open Cup, before the competition was canceled due to the COVID-19 Pandemic.
The 2023 Inter Miami CF season was the fourth season in the history of Inter Miami CF and the 20th season of first-division club soccer in South Florida. In addition to playing in Major League Soccer, the club participated in the U.S. Open Cup and the new-look Leagues Cup for the first time.
The 2023 Philadelphia Union season was the club's fourteenth season in Major League Soccer, the top flight of American soccer. The team was managed by Jim Curtin, his tenth season with the club. The club's regular season began on February 25, 2023, and concluded on October 9. Outside of MLS, Philadelphia will participate in the U.S. Open Cup, the CONCACAF Champions League, and the Leagues Cup.
The 2023 Nashville SC season was the fourth season for Nashville SC as a member of Major League Soccer (MLS), the top flight of professional soccer in the United States. After finishing the 2022 season with a playoff berth and a first round exit, the club loaned out Designated Player and forward Aké Arnaud Loba to Mazatlán F.C. and made trades to add depth. Midfielder Hany Mukhtar had finished the previous season as the league's top goalscorer, earning the MLS Golden Boot with 23 goals, and was also won the most valuable player award.
The 2024 New York Red Bulls season was the the club's twenty-ninth season in Major League Soccer, the top division of soccer in the United States. The club made the MLS Cup final for the first time since 2008.
The 2024 Nashville SC season was the fifth season for Nashville SC as a member of Major League Soccer (MLS), the top flight of professional soccer in the United States.
The 2024 Philadelphia Union season was the club's fifteenth season in Major League Soccer, the top flight of American soccer. The team is managed by Jim Curtin, his eleventh season with the club. The club's regular season began on February 20, 2024, opening with the 2024 CONCACAF Champions Cup after earning its berth by placing third in the 2023 Leagues Cup.
The 2025 CF Montréal season will be the club's 32nd season of existence, and their 14th in Major League Soccer, the top tier of the American soccer pyramid.
The 2025 Atlanta United FC season will be the ninth season of Atlanta United FC's existence, and the seventeenth year that a professional soccer club from Atlanta, Georgia will compete in the top division of American soccer. Atlanta United play their home games at Mercedes-Benz Stadium. Outside of MLS, they will compete in the 2025 U.S. Open Cup and the 2025 Leagues Cup.
The 2025 season will be the fourth season for Charlotte FC in Major League Soccer (MLS), the top flight of professional club soccer in the United States.The team is based in Charlotte, North Carolina, and was established in 2019. They made their MLS debut in the 2022 season. The 2025 season will be their second for Charlotte FC under English head coach Dean Smith, who was hired in December 2023 and was the team's third manager.
The 2025 season will be the 10th season for FC Cincinnati and their 7th in Major League Soccer (MLS), the highest level of men's professional soccer in the United States. Their home stadium is TQL Stadium. It is the fourth season with the club for general manager Chris Albright and head coach Pat Noonan.
The 2025 New York City FC season will be the club's eleventh season in Major League Soccer, the top division of soccer in the United States. The club will split its home games between Yankee Stadium and Citi Field, and play their season opener against Inter Miami CF on February 22, 2025.
The 2025 New York Red Bulls season is the the club's thirtieth season in Major League Soccer, the top division of soccer in the United States.
The 2025 season will be the sixth season for Nashville SC as a member of Major League Soccer (MLS), the top flight of professional soccer in the United States. It is their eighth overall season, including two years in the second-division USL Championship.
The 2025 Orlando City SC season will be the club's 15th season of existence in Orlando and 11th season as a Major League Soccer franchise, the top-flight league in the United States soccer league system.
The 2025 Philadelphia Union season is the club's sixteenth season in Major League Soccer, the top flight of American soccer. The club's regular season began on February 22, 2025, opening against Orlando City SC. The club will also participate in the 2023 Leagues Cup.
The 2025 Toronto FC season is the 19th season in the history of Toronto FC.
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