The 2020 Inter Miami CF season was the first season in the history of Inter Miami CF and the 17th season of first-division club soccer in South Florida. It was the first time since 2001 that a South Florida club competed in the first-division. In addition to playing in Major League Soccer, the club was scheduled to participate in the U.S. Open Cup but the competition was cancelled due to the COVID-19 pandemic.
The 2021 Inter Miami CF season was the second season in the history of Inter Miami CF and the 18th season of first-division club soccer in South Florida. In addition to playing in Major League Soccer, the club was scheduled to participate in the U.S. Open Cup but the competition was cancelled for the second consecutive year due to the COVID-19 pandemic.
The 2021 Nashville SC season was the club's second season as a member of Major League Soccer. This was the club's last season in the Eastern Conference after being added to the Conference in 2020 after the MLS is Back Tournament as the club returns to the Western Conference the following season in 2022 due to the addition of Charlotte FC.
The 2021 New York City FC season was the club's seventh season of competition and its seventh in the top tier of American soccer, Major League Soccer. New York City FC usually played its home games at Yankee Stadium in the New York City borough of The Bronx. Like the 2020 MLS season, the club also played several of their home games at Red Bull Arena in Harrison, New Jersey due to scheduling conflicts with Yankee Stadium and its backup stadium, Citi Field. New York City FC won the clubs' first MLS Cup title by defeating the Portland Timbers 2–4 in penalty shoot-outs with a 1–1 score before going into extra time, in which neither of the teams scored.
The 2022 Columbus Crew season was the club's twenty-seventh season of existence and their twenty-seventh consecutive season in Major League Soccer, the top flight of American soccer. The season covered the period from November 8, 2021 to the end of the 2022 season. It was the fourth and final season under head coach Caleb Porter.
The 2023 Inter Miami CF season was the fourth season in the history of Inter Miami CF and the 20th season of first-division club soccer in South Florida. In addition to playing in Major League Soccer, the club participated in the U.S. Open Cup and the new-look Leagues Cup for the first time.
The 2023 Philadelphia Union season was the club's fourteenth season in Major League Soccer, the top flight of American soccer. The team was managed by Jim Curtin, his tenth season with the club. The club's regular season began on February 25, 2023, and concluded on October 9. Outside of MLS, Philadelphia will participate in the U.S. Open Cup, the CONCACAF Champions League, and the Leagues Cup.
The 2023 Nashville SC season was the fourth season for Nashville SC as a member of Major League Soccer (MLS), the top flight of professional soccer in the United States. After finishing the 2022 season with a playoff berth and a first round exit, the club loaned out Designated Player and forward Aké Arnaud Loba to Mazatlán F.C. and made trades to add depth. Midfielder Hany Mukhtar had finished the previous season as the league's top goalscorer, earning the MLS Golden Boot with 23 goals, and was also won the most valuable player award.
The 2024 Inter Miami CF season was the fifth season in the history of Inter Miami CF and the 21st season of first-division club soccer in South Florida. The team were in their fifth year as a member of the Eastern Conference of Major League Soccer (MLS). In addition to playing in the MLS regular season, the club participated in the MLS Cup playoffs, in the CONCACAF Champions Cup for the first time, and in the Leagues Cup as defending champions.
The 2024 Nashville SC season was the fifth season for Nashville SC as a member of Major League Soccer (MLS), the top flight of professional soccer in the United States.
The 2024 Philadelphia Union season was the club's fifteenth season in Major League Soccer, the top flight of American soccer. The team is managed by Jim Curtin, his eleventh season with the club. The club's regular season began on February 20, 2024, opening with the 2024 CONCACAF Champions Cup after earning its berth by placing third in the 2023 Leagues Cup.
The 2025 Major League Soccer season will be the 30th season of Major League Soccer (MLS), the top professional soccer league in the United States and Canada, and the 47th season overall of a national first-division league in the United States.
The 2025 season will be D.C. United's 30th in existence and its 30th consecutive season in the top division of American soccer, Major League Soccer. Pending announcements from the club, it is expected that the team will participate in the 2025 U.S. Open Cup and the 2025 Leagues Cup in addition to MLS play.
The 2025 CF Montréal season will be the club's 32nd season of existence, and their 14th in Major League Soccer, the top tier of the American soccer pyramid.
The 2025 Atlanta United FC season will be the ninth season of Atlanta United FC's existence, and the seventeenth year that a professional soccer club from Atlanta, Georgia will compete in the top division of American soccer. Atlanta United play their home games at Mercedes-Benz Stadium. Outside of MLS, they will compete in the 2025 U.S. Open Cup and the 2025 Leagues Cup.
The 2025 season will be the fourth season for Charlotte FC in Major League Soccer (MLS), the top flight of professional club soccer in the United States.The team is based in Charlotte, North Carolina, and was established in 2019. They made their MLS debut in the 2022 season. The 2025 season will be their second for Charlotte FC under English head coach Dean Smith, who was hired in December 2023 and was the team's third manager.
The 2025 season will be the 10th season for FC Cincinnati and their 7th in Major League Soccer (MLS), the highest level of men's professional soccer in the United States. Their home stadium is TQL Stadium. It is the fourth season with the club for general manager Chris Albright and head coach Pat Noonan.
The 2025 Columbus Crew season will be the club's 30th season of existence and their 30th consecutive season in Major League Soccer, the top flight of soccer in the United States. It will be their third season under head coach Wilfried Nancy.
The 2025 New York Red Bulls season is the the club's thirtieth season in Major League Soccer, the top division of soccer in the United States.
The 2025 Philadelphia Union season is the club's sixteenth season in Major League Soccer, the top flight of American soccer. The club's regular season began on February 22, 2025, opening against Orlando City SC. The club will also participate in the 2023 Leagues Cup.
