Chlorodiiodomethane

Chlorodiiodomethane

Names
Preferred IUPAC name Chloro(diiodo)methane
Other names Diiodochloromethane, CDIM [1]
Identifiers
CAS Number	638-73-3  Y
3D model (JSmol)	Interactive image
ChemSpider	62699
PubChem CID	69493
UNII	Standard InChI: Copy IUPAC Standard InChI: Copy
CompTox Dashboard (EPA)	DTXSID20213251
InChI InChI=1S/CHClI2/c2-1(3)4/h1H Key: RYPFDEIVUZVDCE-UHFFFAOYSA-N
SMILES C(Cl)(I)I
Properties
Chemical formula	CHClI2
Molar mass	302.28 g·mol−1
Density	3.2±0.1 g/cm³
Boiling point	190.8 °C (375.4 °F; 463.9 K)
Hazards
GHS labelling: [2]
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H319
Flash point	69.2±18.4 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chlorodiiodomethane is a trihalomethane with the chemical formula CHClI₂. ^{[3] [4]}

Toxicity

It is an environmental pollutant and, like other iodine-containing trihalomethanes (except iodoform), is less cytotoxic than the corresponding iodocarboxylic acids. ^{[5] [6]}

Chemical properties

It reacts with sodium hydroxide in the presence of a phase transfer catalyst to produce chloroiodocarbene, which can be added to olefins to produce 1-chloro-1-iodocyclopropane derivatives. ^[7]

References

1. Zandaryaa, Sarantuyaa; Fares, Ali; Eckstein, Gabriel (11 April 2025). Emerging Pollutants: Protecting Water Quality for the Health of People and the Environment. Springer Nature. p. 192. ISBN   978-3-031-71758-1 . Retrieved 29 August 2025.
2. "Chlorodiiodomethane | 1X200MG | CHClI2 | 681546 | 638-73-3". hpc-standards.com. Retrieved 29 August 2025.
3. "Methane, chlorodiiodo-". NIST . Retrieved 29 August 2025.
4. Kotzekidou, Parthena (27 April 2016). Food Hygiene and Toxicology in Ready-to-Eat Foods. Academic Press. p. 430. ISBN   978-0-12-802008-1 . Retrieved 29 August 2025.
5. Alastuey, Andrés; Barceló, Damiá (2012). Emerging organic contaminants and human health. Heidelberg New York: Springer. p. 101. ISBN   978-3-642-28132-7 . Retrieved 29 August 2025.
6. Chen, Chao; Andrews, Susan; Xie, Yuefeng (28 December 2024). Disinfection By-Products in Water. Springer Nature. p. 117. ISBN   978-3-031-74260-6 . Retrieved 29 August 2025.
7. de Meijere, A.; Baird, M.S.; Bertrand, G.; de Kimpe, N.; Fedorynski, M. (2014). Houben-Weyl Methods of Organic Chemistry Vol. E 17a, 4th Edition Supplement: Carbocyclic Three-Membered Ring Compounds, Cyclopropanes: Synthesis (4 ed.). Stuttgart: Thieme. p. 697. ISBN   978-3-13-181944-4 . Retrieved 29 August 2025.