Dacryocystocele

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Dacryocystocele
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Nasolacrimal duct
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Dacryocystocele (Dacryocystitis) or timo cyst is a benign, bluish-gray mass in the inferomedial canthus that develops within a few days or weeks after birth. The uncommon condition forms as a result as a consequence of narrowing or obstruction of the nasolacrimal duct, usually during prenatal development. Nasolacrimal duct obstruction disrupts the lacrimal drainage system, eventually creating a swelling cyst in the lacrimal sac area by the nasal cavity. The location of the cyst can cause respiratory dysfunction, compromising the airway. The obstruction ultimately leads to epiphora, an abundance of tear production. [1]

Contents

Signs and symptoms

Dacryocystocele is a condition that can occur to all, at any age. However, the population most affected by this rare condition are infants. The intensity of the symptoms may vary depending on the type of dacryocystocele. There are three types of dacrycystocele: acute, congenital and chronic. Acute dacryocystocele is a bacterial infection, that includes symptoms such as fever and pus from the eye region. While, chronic dacryocystocele is less severe. People with the chronic form of the condition experience symptoms of pain or discomfort from the corner of the eye. Congenital is the dacryocystocele form that appears in infants. The infant may have watering or discharge from the eyes. [1]

Common symptoms of all types of dacryocystocele include:

Cause

The nasolacrimal ducts drain the excess tears from our eyes into the nasal cavity. In dacryocystocele this tube gets blocked on either end and as a result when mucoid fluid collects in the intermediate patent section it forms a cystic structure.

The infection is often caused by:

Pathophysiology

The nasolacrimal system is located within the maxillary bone. The purpose of the nasolacrimal ducts is to drain tears from the eye area of the lacrimal sac and eventually through the nasal cavity. Dacryocystocele is caused by blockage on the nasolacrimal duct, as a result when mucoid fluid collects in the intermediate patent section it forms a cystic structure. The cyst is formed by the eye and nose region. A blockage of epiphora can become an area for infections to take over. Once an infection occurs, the lacrimal sac will inflame causing swelling and the cystic formation.

Diagnosis

The diagnosis can be made prenatally; routine obstetric ultrasound can identify the characteristic hypoechoic lesion inferior and medial to the globe. It is important to distinguish a dacrocystocele from the more serious encephalocele, which is a neural tube defect.

A dacryocystocele can be diagnosed postpartum with a non-invasive ultrasound (US).

Among the adult population, several tests can be ordered to further diagnose the condition. Initially, a physician would use a patient's medical history or any visible symptoms that can indicate of having the condition. Tests that are used to diagnose a patient include: [1]

Prevention/ Treatment

To relieve dacryocystocele symptoms, a warm compress is placed on the affected area to help open up the ducts. Taking over the counter medication, such as anti-inflammatory and pain relievers are recommended in order to reduce fever and pain symptoms.[ citation needed ]

Since dacryocystocele is an infection of the tear sacs, the condition is resolved by taking oral antibiotics. With acute dacryocystocele the mass may spontaneously resolve or with pressure directed toward the nose. With time the cyst will outgrow the blockage. However, with chronic dacryocystocele, the nasolacrimal duct probing may be required to open the obstruction. Surgery may be needed to widen the tear ducts in order to reduce the blockage occurring in the eye area. The procedure for the surgery is called dacryocystorhinostomy, laser is used to remove some of the bone structure on the nose in order to widen the tear duct.[ citation needed ]

Complications

If the infection is not treated early in the course of the condition, dacryocystocele can lead to life-threatening illnesses: [2]

Prognosis

Recovery for acute dacryocystocele would be a couple of days to 2 weeks, with the help of antibiotics. However, with chronic dacryocystocele recovery time varies. This recovery time all depends if the person with chronic dacryocystocele receives surgery for the condition. Recovery time for the surgery (specifically DCR), is between three and six months. The success rate of the surgery is 93%- 97%.

Mortality and morbidity rates with this condition are significantly low. This condition can have a high success rate if treated early, particularly among infants with congenital dacryocystocele. [3]

Epidemiology

Dacryocystocele is most prominent among infants, the prevalence is 1 in 3884 live births. [3]

90% of the infants with the condition recover by the time they turn a year old. Among the adult population, those 40 years old and older are more likely to develop the condition, especially women. 75% percent of dacryocystocele cases in adult are from women. [3] Women have narrower nasal ducts than men, and are more prone to develop the condition.

Dacryocystocele becomes more prevalent among people with the following pre-existing conditions:

Research Directions

In 2018, a research study was conducted in Northwest Iran among patients with dacryocystocele. The purpose of the research experiment was to examine bacterial and antibiotic susceptibility among the group with the condition. A total of 129 patients with dacryocystitis participated in the study. Patients under the age of eighteen needed written consent for participation. All patients that were referred to the clinic of ophthalmology were selected to participate, exclusion for participation was taken into consideration if the patient had previous treatment with antibiotics.

In order to go forward with the study, nasolacrimal duct discharges were injected into growth medium to isolate and determine microbial agent stains present in the discharges. To test the antibiotic susceptibility among dacryocystocele patients a disc diffusion method was utilize.

From the 129 patients that participated in the experiment, 83 were female and 46 were male patients. Results from the culture sample demonstrated that S. aureus, S. epidermidis, and S. pneumonaie were the most common strains of microorganisms among patients with actue dacryocystitis. However, patients with chronic dacryocystitis, they demonstrated prevalence among the S. epidermidis, Pseudomonas spp., S aureus, and C. albicans strains.

Results from the antibiotic susceptibility tests demonstrated that patients in the Northwest region of Iran were most sensitive to the following antibiotics: ciprofloxacin, ceftriaxone, vancomycin, chloramphenicol, gentamicin, and erythromycin. It is concluded that ciprofloxacin and vancomycin are the most effective medications among the patients with the condition in the region of Iran. This study was beneficial to determine which medications worked best to treat the people of Northwest Iran more adequately. Other regions around the world should take consideration of this study in order to treat dacryocystocele effectively in their regions. [4]

Related Research Articles

<span class="mw-page-title-main">Sinusitis</span> Inflammation of the mucous membrane that lines the sinuses resulting in symptoms

Sinusitis, also known as rhinosinusitis, is inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include thick nasal mucus, a plugged nose, and facial pain. Other signs and symptoms may include fever, headaches, a poor sense of smell, sore throat, a feeling that phlegm is oozing out from the back of the nose to the throat along with a necessity to clear the throat frequently and frequent attacks of cough.

<span class="mw-page-title-main">Tears</span> Clear liquid secreted from glands in eyes of mammals

Tears are a clear liquid secreted by the lacrimal glands found in the eyes of all land mammals. Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. The different types of tears—basal, reflex, and emotional—vary significantly in composition.

<span class="mw-page-title-main">Lacrimal bone</span> Smallest and most fragile bone of the human skull and face

The lacrimal bone is a small and fragile bone of the facial skeleton; it is roughly the size of the little fingernail. It is situated at the front part of the medial wall of the orbit. It has two surfaces and four borders. Several bony landmarks of the lacrimal bone function in the process of lacrimation or crying. Specifically, the lacrimal bone helps form the nasolacrimal canal necessary for tear translocation. A depression on the anterior inferior portion of the bone, the lacrimal fossa, houses the membranous lacrimal sac. Tears or lacrimal fluid, from the lacrimal glands, collect in this sac during excessive lacrimation. The fluid then flows through the nasolacrimal duct and into the nasopharynx. This drainage results in what is commonly referred to a runny nose during excessive crying or tear production. Injury or fracture of the lacrimal bone can result in posttraumatic obstruction of the lacrimal pathways.

<span class="mw-page-title-main">Eye surgery</span> Surgery performed on the eye or its adnexa

Eye surgery, also known as ophthalmic surgery or ocular surgery, is surgery performed on the eye or its adnexa. Eye surgery is part of ophthalmology and is performed by an ophthalmologist or eye surgeon. The eye is a fragile organ, and requires due care before, during, and after a surgical procedure to minimize or prevent further damage. An eye surgeon is responsible for selecting the appropriate surgical procedure for the patient, and for taking the necessary safety precautions. Mentions of eye surgery can be found in several ancient texts dating back as early as 1800 BC, with cataract treatment starting in the fifth century BC. It continues to be a widely practiced class of surgery, with various techniques having been developed for treating eye problems.

<span class="mw-page-title-main">Nasal polyp</span> Noncancerous growths within the nose or sinuses

Nasal polyps (NP) are noncancerous growths within the nose or sinuses. Symptoms include trouble breathing through the nose, loss of smell, decreased taste, post nasal drip, and a runny nose. The growths are sac-like, movable, and nontender, though face pain may occasionally occur. They typically occur in both nostrils in those who are affected. Complications may include sinusitis and broadening of the nose.

<span class="mw-page-title-main">Dry eye syndrome</span> Medical condition

Dry eye syndrome, also known as keratoconjunctivitis sicca, is the condition of having dry eyes. Symptoms include dryness in the eye, irritation, redness, discharge, blurred vision, and easily fatigued eyes. Symptoms range from mild and occasional to severe and continuous. Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system.

<span class="mw-page-title-main">Nasolacrimal duct</span> Carries tears from the lacrimal sac of the eye into the nasal cavity.

The nasolacrimal duct carries tears from the lacrimal sac of the eye into the nasal cavity. The duct begins in the eye socket between the maxillary and lacrimal bones, from where it passes downwards and backwards. The opening of the nasolacrimal duct into the inferior nasal meatus of the nasal cavity is partially covered by a mucosal fold.

<span class="mw-page-title-main">Rhinorrhea</span> Filling of the nasal cavity with fluid mucus

Rhinorrhea, rhinorrhoea, or informally runny nose is the free discharge of a thin mucus fluid from the nose; it is a common condition. It is a common symptom of allergies or certain viral infections, such as the common cold or COVID-19. It can be a side effect of crying, exposure to cold temperatures, cocaine abuse, or drug withdrawal, such as from methadone or other opioids. Treatment for rhinorrhea may be aimed at reducing symptoms or treating underlying causes. Rhinorrhea usually resolves without intervention, but may require treatment by a doctor if symptoms last more than 10 days or if symptoms are the result of foreign bodies in the nose.

An imperforate lacrimal punctum is a congenital disorder of dogs involving the lack of an opening to the nasolacrimal duct in the conjunctiva. Dogs normally have two lacrimal puncta, the superior and inferior. This condition can affect either or both. Symptoms include excessive tearing and tear staining of the hair around the eye. Affected breeds include the American Cocker Spaniel, Bedlington Terrier, Golden Retriever, Poodle, and Samoyed. Imperforate lacrimal puncta can be corrected by surgical opening of the punctum.

<span class="mw-page-title-main">Lacrimal sac</span> Upper, dilated end of the nasolacrimal duct

The lacrimal sac or lachrymal sac is the upper dilated end of the nasolacrimal duct, and is lodged in a deep groove formed by the lacrimal bone and frontal process of the maxilla. It connects the lacrimal canaliculi, which drain tears from the eye's surface, and the nasolacrimal duct, which conveys this fluid into the nasal cavity. Lacrimal sac occlusion leads to dacryocystitis.

Chronic atrophic rhinitis, or simply atrophic rhinitis, is a chronic inflammation of the nose characterised by atrophy of nasal mucosa, including the glands, turbinate bones and the nerve elements supplying the nose. Chronic atrophic rhinitis may be primary and secondary. Special forms of chronic atrophic rhinitis are rhinitis sicca anterior and ozaena. It can also be described as the empty nose syndrome.

Oculoplastics, or oculoplastic surgery, includes a wide variety of surgical procedures that deal with the orbit, eyelids, tear ducts, and the face. It also deals with the reconstruction of the eye and associated structures.

<span class="mw-page-title-main">Dacryocystorhinostomy</span>

Dacryocystorhinostomy (DCR) is a surgical procedure to restore the flow of tears into the nose from the lacrimal sac when the nasolacrimal duct does not function.

<span class="mw-page-title-main">Dacryocystitis</span> Medical condition

Dacryocystitis is an infection of the lacrimal sac, secondary to obstruction of the nasolacrimal duct at the junction of lacrimal sac. The term derives from the Greek dákryon (tear), cysta (sac), and -itis (inflammation). It causes pain, redness, and swelling over the inner aspect of the lower eyelid and epiphora. When nasolacrimal duct obstruction is secondary to a congenital barrier it is referred to as dacryocystocele. It is most commonly caused by Staphylococcus aureus and Streptococcus pneumoniae. The most common complication is corneal ulceration, frequently in association with S. pneumoniae. The mainstays of treatment are oral antibiotics, warm compresses, and relief of nasolacrimal duct obstruction by dacryocystorhinostomy.

A sinus is a sac or cavity in any organ or tissue, or an abnormal cavity or passage caused by the destruction of tissue. In common usage, "sinus" usually refers to the paranasal sinuses, which are air cavities in the cranial bones, especially those near the nose and connecting to it. Most individuals have four paired cavities located in the cranial bone or skull.

<span class="mw-page-title-main">Epiphora (medicine)</span> Medical condition

Epiphora is an overflow of tears onto the face, other than caused by normal crying. It is a clinical sign or condition that constitutes insufficient tear film drainage from the eyes, in that tears will drain down the face rather than through the nasolacrimal system.

Punctoplasty is a surgical procedure to restore proper drainage of tears when the lacrimal punctum becomes blocked in one or both eyes.

<span class="mw-page-title-main">Nasolacrimal duct obstruction</span> Medical condition

Nasolacrimal duct obstruction is the obstruction of the nasolacrimal duct and may be either congenital or acquired. Obstruction of the nasolacrimal duct leads to the excess overflow of tears called epiphora.

Tornwaldt's disease is the inflammation or abscess of the embryonic cyst of pharyngeal bursa. It is located in the midline of the posterior wall of the nasopharynx. It is covered anteriorly by mucosa in the adenoid mass. It is bounded posteriorly by longus muscle.

<span class="mw-page-title-main">Dacryoscintigraphy</span>

Dacryoscintigraphy (DSG), also known as lacrimal scintigraphy, is a nuclear medicine technique for imaging the lacrimal apparatus. It is used to identify obstructions, for example in the lacrimal duct, nasal cavity or nasolacrimal duct.

References

  1. 1 2 3 "Dacryocystitis : Symptoms, Diagnosis and Management". AIMU. 28 February 2017.
  2. "Dacryocystitis". The Lecturio Medical Concept Library. 7 October 2020. Retrieved 11 July 2021.
  3. 1 2 3 Taylor, Roger S.; Ashurst, John V. (26 June 2020). "Dacryocystitis". StatPearls. StatPearls Publishing. PMID   29261989.
  4. Eslami, Fatemeh; Basir, Hamid Reza Ghasemi; Moradi, Abbas; Farah, Shokoufe Heidari (25 September 2018). "Microbiological study of dacryocystitis in northwest of Iran". Clinical Ophthalmology. 12: 1859–1864. doi: 10.2147/OPTH.S175463 . PMC   6165732 . PMID   30310264.

Further reading