Delta11-fatty-acid desaturase

Last updated
Delta11-fatty-acid desaturase
Identifiers
EC no. 1.14.19.5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Delta11-fatty-acid desaturase (EC 1.14.19.5, Delta11 desaturase, fatty acid Delta11-desaturase, TpDESN, Cro-PG, Delta11 fatty acid desaturase, Z/E11-desaturase, Delta11-palmitoyl-CoA desaturase) is an enzyme with systematic name acyl-CoA,hydrogen donor:oxygen Delta11-oxidoreductase. [1] [2] [3] This enzyme catalyses the following chemical reaction

acyl-CoA + reduced acceptor + O2 Delta11-acyl-CoA + acceptor + 2 H2O

The enzyme from the marine microalga Thalassiosira pseudonana desaturates palmitic acid 16:0 to 16:1Delta11, whereas that from the leafroller moth Choristoneura rosaceana desaturates myristic acid 14:0 to 14:1Delta11.

References

  1. ↑ Tonon T, Harvey D, Qing R, Li Y, Larson TR, Graham IA (April 2004). "Identification of a fatty acid Delta11-desaturase from the microalga Thalassiosira pseudonana". FEBS Letters. 563 (1–3): 28–34. doi:10.1016/S0014-5793(04)00241-8. PMID   15063718. S2CID   83206859.
  2. ↑ Hao G, O'Connor M, Liu W, Roelofs WL (2002). "Characterization of Z/E11- and Z9-desaturases from the obliquebanded leafroller moth, Choristoneura rosaceana". J. Insect Sci. 2 (26): 1–7. doi:10.1673/031.002.2601. PMC   355924 . PMID   15455060.
  3. ↑ Rodriguez F, Hallahan DL, Pickett JA, Camps F (1992). "Characterization of the Δ11-palmitoyl-CoA-desaturase from Spodoptera littoralis (Lepidoptera:Noctuidae)". Insect Biochem. Mol. Biol. 22 (2): 143–148. doi:10.1016/0965-1748(92)90152-5.


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.