Etamiphylline

Last updated
Etamiphylline
Etamiphylline.svg
Etamiphylline 3D spacefill.png
Names
Preferred IUPAC name
7-[2-(Diethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.005.678 OOjs UI icon edit-ltr-progressive.svg
KEGG
PubChem CID
UNII
  • InChI=1S/C13H21N5O2/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3/h9H,5-8H2,1-4H3 X mark.svgN
    Key: AWKLBIOQCIORSB-UHFFFAOYSA-N X mark.svgN
  • CCN(CC)CCn1cnc2c1c(=O)n(c(=O)n2C)C
Properties
C13H21N5O2
Molar mass 279.33814
Pharmacology
R03DA06 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
X mark.svgN  verify  (what is  Yes check.svgYX mark.svgN ?)
Infobox references

Etamiphylline or etamiphyllin (INN) [1] is a xanthine intended for use as an anti-asthma agent. It has shown poor to absent effects in human clinical trials. [2] [3]

Related Research Articles

Derek Summerfield is an honorary senior lecturer at London's Institute of Psychiatry and a member of the Executive Committee of Transcultural Special Interest Group at the Royal College of Psychiatry. He is also an Honorary Fellow of the Egyptian Psychiatric Association. He has published around 150 papers and has made other contributions in medical and social sciences literature.

Trisomy X Medical condition

Trisomy X, also known as triple X syndrome and 47,XXX, is a genetic condition in which a female has an extra X chromosome. Those affected are often taller than average. Usually there are no other physical differences and normal fertility. Occasionally there are learning difficulties, decreased muscle tone, seizures, or kidney problems.

Candesartan

Candesartan is an angiotensin receptor blocker used mainly for the treatment of high blood pressure and congestive heart failure.

Vulimiri Ramalingaswami was an Indian medical scientist. His pioneering research on nutrition got him elected to the National Academy of Sciences, Russian Academy of Medical Sciences and the Royal Society of London.

Global health Health of populations in a global context

Global health is the health of populations in the worldwide context; it has been defined as "the area of study, research and practice that places a priority on improving health and achieving equity in health for all people worldwide". Problems that transcend national borders or have a global political and economic impact are often emphasized. Thus, global health is about worldwide health improvement, reduction of disparities, and protection against global threats that disregard national borders. Global health is not to be confused with international health, which is defined as the branch of public health focusing on developing nations and foreign aid efforts by industrialized countries. Global health can be measured as a function of various global diseases and their prevalence in the world and threat to decrease life expectancy in the present day.

Sir Richard Peto is an English statistician and epidemiologist who is Professor of Medical Statistics and Epidemiology at the University of Oxford, England.

Viral pneumonia is a pneumonia caused by a virus. Pneumonia is an infection that causes inflammation in one or both of the lungs. The pulmonary alveoli fill with fluid or pus making it difficult to breathe. Pneumonia can be caused by bacteria, viruses, fungi or parasites. Viruses are the most common cause of pneumonia in children, while in adults bacteria are a more common cause.

Edrecolomab is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A), which is expressed on epithelial tissues and on various carcinomas.

Clofibrate

Clofibrate is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It belongs to the class of fibrates. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well.

The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI) is a cardiology research group founded as a collaboration between two Italian organisations – the Mario Negri Institute and the Associazione Nazionale dei Medici Cardiologi Ospedalieri (ANMCO).

International Community for the Relief of Suffering and Starvation (ICROSS) is an international non-governmental organisation that provides health and development services for pastoral communities in East Africa.

Anatoly Koryagin

Anatoly Ivanovich Koryagin is a psychiatrist and Soviet dissident. He holds a Candidate of Science degree. Along with others, he exposed political abuse of psychiatry in the Soviet Union. He pointed out Russia constructed psychiatric prisons to punish dissidents.

ResearcherID is an identifying system for scientific authors. The system was introduced in January 2008 by Thomson Reuters.

Vera Rich

Vera Rich was a British poet, journalist, historian, and translator from Belarusian and Ukrainian.

Institute for Health Metrics and Evaluation Statistics institute for public health under the University of Washington, based in Seattle

The Institute for Health Metrics and Evaluation (IHME) is a research institute working in the area of global health statistics and impact evaluation at the University of Washington in Seattle. The Institute is headed by Christopher J.L. Murray, a physician and health economist, and professor at the University of Washington Department of Global Health, which is part of the School of Medicine. IHME conducts research and trains scientists, policymakers, and the public in health metrics concepts, methods, and tools. Its mission includes judging the effectiveness and efficacy of health initiatives and national health systems. IHME also trains students at the post-baccalaureate and post-graduate levels.

The Hunterian Oration is a lecture of the Royal College of Surgeons of England. The oration was founded in 1813 by the executors of the will of pioneering surgeon John Hunter, his nephew Dr Matthew Baillie and his brother-in-law Sir Everard Home, who made a gift to the College to provide an annual oration and a dinner for Members of the Court of Assistants and others. In 1853, the oration and dinner became biennial; it is held on alternate years in rotation with the Bradshaw Lecture. It is delivered by a Fellow or Member of the college on 14 Feb, Hunter's birthday, "such oration to be expressive of the merits in comparative anatomy, physiology, and surgery, not only of John Hunter, but also of all persons, as should be from time to time deceased, whose labours have contributed to the improvement or extension of surgical science". The RCS Oration is not to be confused with the Hunterian Society Oration given at the Hunterian Society.

Anthony Costello British paediatrician

Anthony Costello is a British paediatrician. Until 2015 Costello was Professor of International Child Health and Director of the Institute for Global Health at the University College London. Costello is most notable for his work on improving survival among mothers and their newborn infants in poor populations of developing countries. From 2015 to 2018 he was director of maternal, child and adolescent health at the World Health Organization in Geneva.

Daniel J. Drucker

Daniel Joshua Drucker is a Canadian endocrinologist. A Fellow of the Royal Society, he is a professor of medicine at the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto. He is known for his research into intestinal hormones and their use in the treatment of diabetes and other metabolic diseases.

Planetary health refers to "the health of human civilization and the state of the natural systems on which it depends". In 2015, the Rockefeller Foundation and The Lancet launched the concept as the Rockefeller Foundation–Lancet Commission on Planetary Health.

Oriol Mitjà

Oriol Mitjà i Villar is a Catalan-born Spanish researcher and consultant physician in internal medicine and infectious diseases with expertise in poverty-related tropical diseases. He has conducted research at the Lihir Medical Centre in Papua New Guinea since 2010 on new diagnostic and therapeutic tools to eradicate yaws. He was awarded the Princess of Girona Award in the scientific research category. Currently at the Germans Trias i Pujol Research Institute, Mitjà is conducting research on SARS-CoV-2 coronavirus disease (COVID-19) and strategies to control the infection at a community level.

References

  1. "International Non-Proprietary Names for Pharmaceutical Preparations. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 3" (PDF). World Health Organization. p. 467. Retrieved 29 December 2016.
  2. Vazquez, C; Labayru, T; Rodriguez-Soriano, J (1984). "Poor bronchodilator effect of oral etamiphylline in asthmatic children". Lancet. 1 (8382): 914. doi:10.1016/s0140-6736(84)91380-1. PMID   6143224.
  3. Addis, GJ (1984). "Absence of bronchodilatory effect from etamiphylline". Lancet. 1 (8385): 1083. doi:10.1016/s0140-6736(84)91497-1. PMID   6144017.