Etamiphylline

Etamiphylline
Names
	Preferred IUPAC name 7-[2-(Diethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Identifiers
CAS Number	314-35-2 ;
3D model (JSmol)	Interactive image ;
ChemSpider	26354 ;
ECHA InfoCard	100.005.678
KEGG	D07378 ;
PubChem CID	28329 ;
UNII	221A91BQ2S ;
CompTox Dashboard (EPA)	DTXSID10861866 ;
	InChI InChI=1S/C13H21N5O2/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3/h9H,5-8H2,1-4H3 Key: AWKLBIOQCIORSB-UHFFFAOYSA-N ;
	SMILES CCN(CC)CCn1cnc2c1c(=O)n(c(=O)n2C)C;
Properties
Chemical formula	C13H21N5O2
Molar mass	279.33814
Pharmacology
ATC code	R03DA06 ( WHO )
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Last updated December 31, 2025

Etamiphylline or etamiphyllin (INN)^[1] is a xanthine intended for use as an anti-asthma agent. It has shown poor to absent effects in human clinical trials.^[2]^[3]

References

↑ "International Non-Proprietary Names for Pharmaceutical Preparations. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 3" (PDF). World Health Organization. p. 467. Retrieved 29 December 2016.
↑ Vazquez, C; Labayru, T; Rodriguez-Soriano, J (1984). "Poor bronchodilator effect of oral etamiphylline in asthmatic children". Lancet. 1 (8382): 914. doi:10.1016/s0140-6736(84)91380-1. PMID 6143224.
↑ Addis, GJ (1984). "Absence of bronchodilatory effect from etamiphylline". Lancet. 1 (8385): 1083. doi:10.1016/s0140-6736(84)91497-1. PMID 6144017.

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[INN-1] "International Non-Proprietary Names for Pharmaceutical Preparations. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 3" (PDF). World Health Organization. p. 467. Retrieved 29 December 2016.

[2] Vazquez, C; Labayru, T; Rodriguez-Soriano, J (1984). "Poor bronchodilator effect of oral etamiphylline in asthmatic children". Lancet. 1 (8382): 914. doi:10.1016/s0140-6736(84)91380-1. PMID 6143224.

[3] Addis, GJ (1984). "Absence of bronchodilatory effect from etamiphylline". Lancet. 1 (8385): 1083. doi:10.1016/s0140-6736(84)91497-1. PMID 6144017.

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Names


Preferred IUPAC name 7-[2-(Diethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Identifiers
CAS Number	314-35-2 ^Y
3D model (JSmol)	Interactive image
ChemSpider	26354 ^N
ECHA InfoCard	100.005.678
KEGG	D07378 ^Y
PubChem CID	28329
UNII	221A91BQ2S ^Y
CompTox Dashboard (EPA)	DTXSID10861866
InChI InChI=1S/C13H21N5O2/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3/h9H,5-8H2,1-4H3^N Key: AWKLBIOQCIORSB-UHFFFAOYSA-N^N
SMILES CCN(CC)CCn1cnc2c1c(=O)n(c(=O)n2C)C
Properties
Chemical formula	C₁₃H₂₁N₅O₂
Molar mass	279.33814
Pharmacology
ATC code	R03DA06 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references