Mycobacterium tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, M. tuberculosis can appear weakly Gram-positive. Acid-fast stains such as Ziehl–Neelsen, or fluorescent stains such as auramine are used instead to identify M. tuberculosis with a microscope. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, culture, and polymerase chain reaction.
Mycobacterium is a genus of Actinomycetota, given its own family, the Mycobacteriaceae. Over 190 species are recognized in this genus. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis and leprosy in humans. The Greek prefix myco- means 'fungus', alluding to the way mycobacteria have been observed to grow in a mold-like fashion on the surface of cultures. It is acid-fast and cannot be stained by the Gram stain procedure.
Mycolic acids are long fatty acids found in the cell walls of the Mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis. They form the major component of the cell wall of mycolata species. Despite their name, mycolic acids have no biological link to fungi; the name arises from the filamentous appearance their presence gives mycolata under high magnification. The presence of mycolic acids in the cell wall also gives mycolata a distinct gross morphological trait known as "cording". Mycolic acids were first isolated by Stodola et al. in 1938 from an extract of M. tuberculosis.
Mycobacterium bohemicum is a species of the phylum Actinomycetota, belonging to the genus Mycobacterium.
Mycobacterium caprae is a species of bacteria in the genus Mycobacterium and a member of the Mycobacterium tuberculosis complex. The species is named after the caprines, the organisms from which M. caprae was first isolated. Prior to 2003, the species was referred to as Mycobacterium tuberculosis subsp. caprae. It is also synonymous with the name Mycobacterium bovis subsp. caprae.
Mycolicibacter kumamotonensis is a species of bacteria.
Etymology: kumamotonensis, pertaining to Kumamoto Prefecture in Japan, where the type strain was isolated.
Mycolicibacter terrae is a slow-growing species of mycobacteria. It is an ungrouped member of the third Runyon. It is known to cause serious skin infections, which are "relatively resistant to antibiotic therapy".
Mycolicibacter is a genus of Gram-Positive rod-shaped bacteria in the family Mycobacteriaceae from the order Mycobacteriales.
Mycolicibacillus koreensis is a slow-growing, non-chromogenic species of Mycolicibacillus originally isolated from the sputum of a human patient. It grows at temperatures from 25–37 °C and is susceptible to quinolones. The genome of M. koreensis contains a tRNA array that contains a long non-coding RNA called GOLDD.
Mycolicibacillus parakoreensis is a slow-growing, non-chromogenic species of Mycolicibacillus originally isolated from the sputum of a human patient. It is susceptible to amikacin, clarithromycin, and rifampin.
Mycobacteroides franklinii is a species of bacteria from the phylum Actinomycetota belonging to the genus Mycobacteroides. Most of the original strains were isolated from clinical specimens in Pennsylvania, but some have been found in conduit water in the Netherlands. In general, human M. franklinii infections present with symptoms similar to an infection with Mycobacteroides abscessus, but it can also be associated with tattoo infections. M. franklinii is also associated with outbreaks of mycobacteriosis in farmed fish. M. fanklinii is susceptible to cefoxitin and bedaquiline.
Mycobacteroides salmoniphilum is a species of bacteria from the phylum Actinomycetota belonging to the genus Mycobacteroides. It was first identified as the causative agent of mycobacteriosis in chinook salmon and steelhead trout, but has since been found to cause disease in Atlantic cod, Atlantic salmon, burbot, coho salmon, freshwater ornamental fish, and Russian sturgeon. It has also been isolated from tap water. It is not known to infect humans. M. salmoniphilum is susceptible to amikacin.
Mycolicibacter algericus is a species of bacteria from the phylum Actinomycetota that was first isolated from the lung lesion of a goat. It is non-pigmented and grows slowly at 25–42 °C on Löwenstein–Jensen medium. It has also been isolated from freshwater fish, fresh produce, water treatment plant sludge, and a natural cave.
Mycolicibacter engbaekii is a species of bacteria from the phylum Actinomycetota. It is susceptible to amikacin, clarithromycin, ethambutol, linezolid, and rifabutin. It has also been recovered from African tuberculosis patients, water treatment plant sludge, and dairy cattle.
Mycolicibacter heraklionensis is a species of bacteria from the phylum Actinomycetota. It is susceptible to clarithromycin. It is known to cause tenosynovitis in humans, but has also been isolated from sputum, urine, and a soft-tissue ankle mass.
Mycolicibacter longobardus is a species of bacteria from the phylum Actinomycetota. It is susceptible to sulfamethoxazole and clarithromycin. It has been associated with cases of osteomyelitis and an epidermal inclusion cyst of the hand,
"Mycolicibacter virginiensis" is a species of bacteria from the phylum Actinomycetota. It is susceptible to clarithromycin, ethambutol, rifabutin, and TMP-SMX. It has been isolated from cases of tenosynovitis, swine farm mud, bovine feces, sputum, and diseased dromedaries.
"Mycolicibacter icosiumassiliensis" is a species of bacteria from the phylum Actinomycetota.
Mycolicibacter minnesotensis is a species of bacteria from the phylum Actinomycetota that was first isolated from a sphagnum peat bog. It is pink-pigmented and grows at 27–34 °C. It has also been isolated from fresh produce and water treatment plant sludge.
