Supercentenarian

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Supercentenarian Maria Branyas (1907-2024) celebrating her 117th birthday Maria Branyas Morera (117e aniversari).jpg
Supercentenarian Maria Branyas (1907–2024) celebrating her 117th birthday

A supercentenarian, sometimes hyphenated as super-centenarian, is a person who is 110 years or older. This age is achieved by about one in 1,000 centenarians. [1] Supercentenarians typically live a life free of significant age-related diseases until shortly before the maximum human lifespan is reached. [2] [3]

Contents

Etymology

The term "supercentenarian" has been used since 1832 or earlier. [4] Norris McWhirter, editor of Guinness World Records , used the term in association with age claims researcher A. Ross Eckler Jr. in 1976, and the term was further popularised in 1991 by William Strauss and Neil Howe in their book Generations .

The term "semisupercentenarian", has been used to describe someone aged 105-109. Originally the term "supercentenarian" was used to mean someone well over the age of 100, but 110 years and over became the cutoff point of accepted criteria for demographers. [2] [5]

Incidence

The Gerontology Research Group maintains a top 30–40 list of oldest verified living people. The researchers estimate, based on a 0.15% to 0.25% survival rate of centenarians until the age of 110, that there should be between 300 and 450 living supercentenarians in the world. [6] [7] A study conducted in 2010 by the Max Planck Institute for Demographic Research found 663 validated supercentenarians, living and dead, and showed that the countries with the highest total number (not frequency) of supercentenarians (in decreasing order) were the United States, [8] Japan, England plus Wales, France, and Italy. [1] [9] The first verified supercentenarian in human history was Dutchman Geert Adriaans Boomgaard (1788–1899), [10] and it was not until the 1980s that the oldest verified age surpassed 115.

History

Jeanne Calment age 20.jpg
Jeanne Calment is the oldest verified supercentenarian and the only verified person to reach the age of 120.

While claims of extreme age have persisted from the earliest times in history, the earliest supercentenarian accepted by Guinness World Records is Dutchman Thomas Peters (reportedly c. 1745–1857).[ citation needed ] However, Peters's age cannot be reliably verified due to an absence of any documents recording his early life. [11] Other scholars, such as French demographer Jean-Marie Robine, consider Geert Adriaans Boomgaard, also of the Netherlands, who turned 110 in 1898, to be the first verifiable case, as the alleged evidence for Peters has apparently been lost. The evidence for the 112 years of Englishman William Hiseland (reportedly 1620–1732) does not meet the standards required by Guinness World Records. [12]

Church of Norway records, the accuracy of which is subject to dispute, also show what appear to be several supercentenarians who lived in the south-central part of present-day Norway during the 16th and 17th centuries, including Johannes Torpe (1549–1664),[ citation needed ] and Knud Erlandson Etun (1659–1770),[ citation needed ] both residents of Valdres, Oppland.[ citation needed ]

In 1902, Margaret Ann Neve, born in 1792, became the first verified female supercentenarian. [13]

Jeanne Calment of France, who died in 1997 aged 122 years, 164 days, had the longest human lifespan documented. The oldest man ever verified is Jiroemon Kimura of Japan, who died in 2013 aged 116 years and 54 days. [14]

Tomiko Itooka (born 23 May 1908) of Japan is the world's oldest living person, aged 116 years, 220 days. João Marinho Neto (born 5 October 1912) of Brazil is the world's oldest living man, aged 112 years, 85 days. [15] [16]

Research into centenarians

Research into centenarians helps scientists understand how an ordinary person might live longer. [17] [18] [19]

Organisations that research centenarians and supercentenarians include the GRG, LongeviQuest, and the Supercentenarian Research Foundation. [20]

In May 2021, whole genome sequencing analysis of 81 Italian semi-supercentenarians and supercentenarians were published, along with 36 control group people from the same region who were simply of advanced age. [21]

Morbidity

Research on the morbidity of supercentenarians has found that they remain free of major age-related diseases (e.g., stroke, cardiovascular disease, dementia, cancer, Parkinson's disease and diabetes) until the very end of life when they die of exhaustion of organ reserve, which is the ability to return organ function to homeostasis. [2] About 10% of supercentenarians survive until the last three months of life without major age-related diseases, as compared to only 4% of semi-supercentenarians and 3% of centenarians. [2]

By measuring the biological age of various tissues from supercentenarians, researchers may be able to identify the nature of those that are protected from ageing effects. According to a study of 30 different body parts from a 112-year-old female supercentenarian, along with younger controls, the cerebellum is protected from ageing, according to an epigenetic biomarker of tissue age known as the epigenetic clock—the reading is about 15 years younger than expected in a centenarian. [22] These findings could explain why the cerebellum exhibits fewer neuropathological hallmarks of age-related dementia as compared to other brain regions.

A 2021 genomic study identified genetic characteristics that protect against age-related diseases, particularly variants that improve DNA repair. Five variants were found to be significant, affecting STK17A (increased expression) and COA1 (reduced expression) genes. Supercentenarians also had an unexpectedly low level of somatic mutations. [23]

See also

Related Research Articles

A centenarian is a person who has reached the age of 100 years. Because life expectancies worldwide are below 100, the term is invariably associated with longevity. The United Nations estimated that there were 316,600 living centenarians worldwide in 2012, and 573,000 in 2020, almost quadruple the 2000 estimate of 151,000.

<span class="mw-page-title-main">Jeanne Calment</span> French supercentenarian with the longest documented human lifespan (1875–1997)

Jeanne Louise Calment was a French supercentenarian and, with a documented lifespan of 122 years and 164 days, the oldest person ever whose age has been verified. Her longevity attracted media attention and medical studies of her health and lifestyle. She is the only person in history who has been verified to have reached the age of 120.

Thomas Peter Thorvald Kristian Ferdinand Mortensen, known as Christian Mortensen, was a Danish-American supercentenarian who resided in California. When he died, his age of 115 years and 252 days was the longest verified male lifespan at the time, until Jiroemon Kimura surpassed him in 2012. Mortensen was baptized in Fruering Church on December 26, 1882. Besides his baptismal record, other records include the 1890 and 1901 census enumerations in Denmark, and church confirmation in 1896.

Longevity claims are unsubstantiated cases of asserted human longevity. Those asserting lifespans of 110 years or more are referred to as supercentenarians. Many have either no official verification or are backed only by partial evidence. Cases where longevity has been fully verified, according to modern standards of longevity research, are reflected in an established list of supercentenarians based on the work of organizations such as the Gerontology Research Group (GRG) or Guinness World Records. This article lists living claims greater than that of the oldest living person whose age has been independently verified, Japanese woman Tomiko Itooka, aged 116 years, 219 days, and deceased claims greater than that of the oldest person ever whose age has been verified, French woman Jeanne Calment, who died aged 122 years and 164 days. The upper limit for both lists is 130 years.

<span class="mw-page-title-main">Oldest people</span>

This is a list of tables of the oldest people in the world in ordinal ranks. To avoid including false or unconfirmed claims of old age, names here are restricted to those people whose ages have been validated by an international body dealing in longevity research, such as the Gerontology Research Group or Guinness World Records, and others who have otherwise been reliably sourced.

<span class="mw-page-title-main">Gerontology Research Group</span> Global researcher group

The Gerontology Research Group (GRG) based in Los Angeles, California, US, is a global non-profit scientific organization of researchers in various fields of gerontology, primarily concerned with validating the ages of, recording and researching supercentenarians.

Jean-Marie Robine is a French social scientist, who works in the field of demography and gerontology, and is an author and journalist, who is best known as being the co-validator of the longevity of Jeanne Calment, the oldest verified supercentenarian of all time, with whom he collaborated.

A centenarian is a person who has attained the age of 100 years or more. Research on centenarians has become more common with clinical and general population studies now having been conducted in France, Hungary, Japan, Italy, Finland, Denmark, the United States, and China. Centenarians are the second fastest-growing demographic in much of the developed world. By 2030, it is expected that there will be around a million centenarians worldwide. In the United States, a 2010 Census Bureau report found that more than 80 percent of centenarians are women.

References

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  2. 1 2 3 4 Anderson, Stacy L.; Sebastiani, Paola; Dworkis, Daniel A.; Feldman, Lori; Perls, Thomas T. (4 January 2012). "Health Span Approximates Life Span Among Many Supercentenarians: Compression of Morbidity at the Approximate Limit of Life Span". The Journals of Gerontology: Series A. 67A (4): 395–405. doi:10.1093/gerona/glr223. PMC   3309876 . PMID   22219514.
  3. B. M. Weon & J. H. Je (17 June 2008). "Theoretical estimation of maximum human lifespan". Biogerontology. 10 (1): 65–71. doi:10.1007/s10522-008-9156-4. PMID   18560989. S2CID   8554128.
  4. "Oxford English Dictionary". Oxford English Dictionary. Oxford University Press. Retrieved 27 July 2024.
  5. Gibb, G. (1876). "Ultra-centenarian Longevity". The Journal of the Anthropological Institute of Great Britain and Ireland. 5. Royal Anthropological Institute of Great Britain and Ireland: 82–101. doi:10.2307/2841365. JSTOR   2841365.
  6. "GRG World Supercentenarian Rankings List". Gerontology Research Group. 23 November 2020. Archived from the original on 26 November 2020. — see note 2 at bottom of page)
  7. "GRG World Supercentenarian Rankings List". Gerontology Research Group. 9 April 2021. Retrieved 12 April 2021. — see note 2 at bottom of page)
  8. Rosenwaike, Ira; Stone, Leslie F. (2003). "Verification of the Ages of Supercentenarians in the United States: Results of a Matching Study". Demography. 40 (4): 727–739. doi: 10.1353/dem.2003.0038 . JSTOR   1515205. PMID   14686139. S2CID   22168523.
  9. CSMonitor Staff (10 August 2010). "Supercentenarians around the world". The Christian Science Monitor . Retrieved 13 April 2017.
  10. Jeune, Bernard; Poulain, Michel (2021). "The First Supercentenarians in History, and Recent 115 + −Year-Old Supercentenarians. An Introduction to the Following Chapters". In Maier, Heiner; Jeune, Bernard Jeune; Vaupel, James W. (eds.). Exceptional Lifespans. Demographic Research Monographs. Springer. p. 206. doi:10.1007/978-3-030-49970-9_14. ISBN   978-3-030-49969-3.
  11. "How are records measured?". Guinness World Records. Retrieved 15 July 2023.
  12. Young, Thomas Emley (1899). On centenarians; and the duration of the human race : a fresh and authentic enquiry; with historical notes, criticisms, and speculations. Columbia University Libraries. London, C. and E. Layton.
  13. "World's oldest man ever passes away aged 116". Guinness World Records. 12 June 2013. Retrieved 15 July 2023.[ dead link ]
  14. Atwal, Sanj (21 August 2024). "116-year-old Japanese woman confirmed as world's oldest living person". Guinness World Records . Retrieved 27 November 2024.
  15. Maglov, Stefan (26 November 2024). "João Marinho Neto Becomes the World's Oldest Living Man at 112 Years Old". LongeviQuest. Retrieved 27 November 2024.
  16. Rachel Nuwer (4 July 2014). "Keeping Track of the Oldest People in the World". Smithsonian .
  17. Gayle White (8 February 2006). "Supercentenarians giving researchers clues on longevity". Chicago Tribune . Cox News Service.
  18. "Longevity gene keeps mind sharp". BBC News . 26 December 2006.
  19. "Mission Statement". Supercentenarian Research Foundation."
  20. Garagnani, Paolo; et al. (5 April 2021). "Whole-genome sequencing analysis of semi-supercentenarians". eLife . 10: e57849. doi: 10.7554/eLife.57849 . PMC   8096429 . PMID   33941312.
  21. Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, Vinters HV, Coles LS (2015). "The cerebellum ages slowly according to the epigenetic clock". Aging. 7 (5): 294–306. doi:10.18632/aging.100742. PMC   4468311 . PMID   26000617.
  22. Haridy, Rich (5 May 2021). "Biggest genetic study of supercentenarians reveals clues to healthy aging". New Atlas. Retrieved 5 May 2021.