Vegetation (pathology)

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Histopathology of a vegetation of bacterial endocarditis, taken from a valve repair, H&E stain. Histopathology of vegetation of bacterial endocarditis.jpg
Histopathology of a vegetation of bacterial endocarditis, taken from a valve repair, H&E stain.

In medicine, a vegetation is an abnormal growth [1] named for its similarity to natural vegetation. Vegetations are often associated with endocarditis. [2] [3] [4] They can be made of fibrin [5] and platelets. [6]

Types

Certain conditions are associated with specific vegetation patterns:

ConditionSizeInfective?
Infective endocarditis related to Staphylococcus aureus Generally largeYes
Rheumatic fever related to Streptococcus pyogenes Typically small
Libman–Sacks endocarditis related to systemic lupus erythematosus SmallNo (sterile)
Nonbacterial thrombotic endocarditis (NBTE)SmallNo (sterile)

References

  1. "Vegetation" at Dorland's Medical Dictionary
  2. Miyata E, Satoh S, Inokuchi K, et al. (September 2007). "Three fatal cases of rapidly progressive infective endocarditis caused by Staphylococcus aureus: one case with huge vegetation". Circ. J. 71 (9): 1488–91. doi: 10.1253/circj.71.1488 . PMID   17721034.
  3. Gotsman I, Meirovitz A, Meizlish N, Gotsman M, Lotan C, Gilon D (May 2007). "Clinical and echocardiographic predictors of morbidity and mortality in infective endocarditis: the significance of vegetation size". Isr. Med. Assoc. J. 9 (5): 365–9. PMID   17591374.
  4. "eMedicine/Stedman Medical Dictionary Lookup!". Archived from the original on 2008-02-16.
  5. "Pathology Education: Cardiovascular". Archived from the original on 2008-09-21. Retrieved 2008-07-29.
  6. "eMedicine/Stedman Medical Dictionary Lookup!". Archived from the original on 2008-02-16.