CDH6 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | CDH6 , CAD6, KCAD, cadherin 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 603007; MGI: 107435; HomoloGene: 21027; GeneCards: CDH6; OMA:CDH6 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Cadherin-6 is a protein that in humans is encoded by the CDH6 gene. [5] [6] [7]
This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell–cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell–cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [7]
Keratin 13 is a protein that in humans is encoded by the KRT13 gene.
Cadherin EGF LAG seven-pass G-type receptor 3 is a protein that in humans is encoded by the CELSR3 gene.
Cadherin EGF LAG seven-pass G-type receptor 2 is a protein that in humans is encoded by the CELSR2 gene.
Cadherin-3, also known as P-Cadherin, is a protein that in humans is encoded by the CDH3 gene.
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.
Cadherin-4 is a protein that in humans is encoded by the CDH4 gene.
Inversin is a protein that in humans is encoded by the INVS gene.
Cadherin-15 is a protein that in humans is encoded by the CDH15 gene.
Cadherin-16 is a protein that in humans is encoded by the CDH16 gene.
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
DnaJ homolog subfamily A member 2 is a protein that in humans is encoded by the DNAJA2 gene.
Angiopoietin-4 is a protein that in humans is encoded by the ANGPT4 gene.
Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.
Protocadherin-8 is a protein that in humans is encoded by the PCDH8 gene.
Cadherin-12 is a protein that in humans is encoded by the CDH12 gene.
Protocadherin-17 is a protein that in humans is encoded by the PCDH17 gene.
Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.
Cadherin-8 is a protein that in humans is encoded by the CDH8 gene.
Cadherin 10 is a protein that in humans is encoded by the CDH10 gene.
Cadherin 9 is a protein that in humans is encoded by the CDH9 gene.