Cadherin 9 is a protein that in humans is encoded by the CDH9 gene. [5] [6]
Cadherin 9 is a protein that in humans is encoded by the CDH9 gene. [5] [6]
T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. Classical cadherins are necessary for cell–cell contacts, dynamic regulation of morphogenetic processes in embryos and tissue integrity in adult organism. Cadherins function as membrane receptors mediating outside-in signals, activating small GTPases and beta-catenin/Wnt pathway, and resulting in dynamic cytoskeleton reorganization and changes in the phenotype.
N-cadherin, also known as Cadherin-2 (CDH2) or neural cadherin (NCAD) is a protein that in humans is encoded by the CDH2 gene. CDH2 has also been designated as CD325. N-cadherin is a transmembrane protein expressed in multiple tissues and functions to mediate cell–cell adhesion. In cardiac muscle, N-cadherin is an integral component in adherens junctions residing at intercalated discs, which function to mechanically and electrically couple adjacent cardiomyocytes. Alterations in expression and integrity of N-cadherin protein has been observed in various forms of disease, including human dilated cardiomyopathy. Variants in CDH2 have also been identified to cause a syndromic neurodevelopmental disorder.
Cadherin 5, type 2 or VE-cadherin also known as CD144, is a type of cadherin. It is encoded by the human gene CDH5.
Cadherin-23 is a protein that in humans is encoded by the CDH23 gene.
Cadherin-3, also known as P-Cadherin, is a protein that in humans is encoded by the CDH3 gene.
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.
Cadherin-4 is a protein that in humans is encoded by the CDH4 gene.
Cadherin-6 is a protein that in humans is encoded by the CDH6 gene.
Cadherin-15 is a protein that in humans is encoded by the CDH15 gene.
Cadherin-16 is a protein that in humans is encoded by the CDH16 gene.
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.
Cadherin-12 is a protein that in humans is encoded by the CDH12 gene.
Protocadherin-17 is a protein that in humans is encoded by the PCDH17 gene.
P2X purinoceptor 6 is a protein that in humans is encoded by the P2RX6 gene.
Cadherin-8 is a protein that in humans is encoded by the CDH8 gene.
Protocadherin-12 is a protein that in humans is encoded by the PCDH12 gene.
Cadherin-1 also known as CAM 120/80 or epithelial cadherin (E-cadherin) or uvomorulin is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. CDH1 has also been designated as CD324. It is a tumor suppressor gene.
Protocadherin-20 is a protein that in humans is encoded by the PCDH20 gene.
Cadherin 10 is a protein that in humans is encoded by the CDH10 gene.
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