| Chlorophyllide a reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.7.15 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Chlorophyllide a reductase (EC 1.3.7.15), also known as COR, is an enzyme with systematic name bacteriochlorophyllide-a:ferredoxin 7,8-oxidoreductase. [1] [2] It catalyses the following chemical reaction
- chlorophyllide a + 2 reduced ferredoxin + ATP + H2O + 2 H+ 3-deacetyl 3-vinylbacteriochlorophyllide a + 2 oxidized ferredoxin + ADP + phosphate
- Structure of the substrate and product of the enzyme
Chlorophyllide a
Bacteriochlorophyllide a (R=H). The product of COR retains the vinyl group of the substrate in place of the acetyl group shown
This reduction (with trans stereochemistry) of the pyrrole ring B gives the characteristic 18-electron aromatic system that distinguishes bacteriochlorophylls from chlorophylls, which retain the chlorin system of chlorophyllide a. This enzyme is present in purple bacteria such as Rhodobacter capsulatus and Rhodobacter sphaeroides , and Pseudomonadota. It is a component of the biosynthetic pathway to bacteriochlorophylls. [3] [4] [5]
