DNPEP

Last updated
DNPEP
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DNPEP , ASPEP, DAP, aspartyl aminopeptidase
External IDs OMIM: 611367; MGI: 1278328; HomoloGene: 6110; GeneCards: DNPEP; OMA:DNPEP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001110831
NM_016878

RefSeq (protein)

NP_001104301
NP_058574

Location (UCSC) Chr 2: 219.37 – 219.4 Mb Chr 1: 75.28 – 75.29 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Aspartyl aminopeptidase is an enzyme that in humans is encoded by the DNPEP gene. [5] [6]

Function

The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in the general metabolism of intracellular proteins. [6]

See also

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000123992 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026209 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Wilk S, Wilk E, Magnusson RP (Jun 1998). "Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase". The Journal of Biological Chemistry. 273 (26): 15961–70. doi: 10.1074/jbc.273.26.15961 . PMID   9632644.
  6. 1 2 "Entrez Gene: DNPEP aspartyl aminopeptidase".

Further reading