Gingipain K

Gingipain K
Identifiers
EC no.	3.4.22.47
CAS no.	159745-69-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Gingipain K (EC 3.4.22.47, Lys-gingipain, PrtP proteinase) is an enzyme. ^{[1] [2]} This enzyme catalyses the following chemical reaction:

Endopeptidase with strict specificity for lysyl bonds

Activity of this enzyme is stimulated by glycine.

See also

• Gingipain
  • Gingipain R

References

1. Pike R, McGraw W, Potempa J, Travis J (January 1994). "Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins". The Journal of Biological Chemistry. 269 (1): 406–11. doi: 10.1016/S0021-9258(17)42365-9 . PMID   8276827.
2. Curtis MA, Aduse Opoku J, Rangarajan M, Gallagher A, Sterne JA, Reid CR, Evans HE, Samuelsson B (December 2002). "Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor". Infection and Immunity. 70 (12): 6968–75. doi:10.1128/iai.70.12.6968-6975.2002. PMC   132948 . PMID   12438376.

External links

• Gingipain+K at the U.S. National Library of Medicine Medical Subject Headings (MeSH)