Highway 20, more commonly known as the Ayalon Highway, or simply Ayalon, is a major inter city freeway in Gush Dan, Israel. The road runs along the eastern border of central Tel Aviv from north to south and connects all of the major highways leading to the city—such as Highway 4 from Ashdod and the Southern regions, Highway 2 from Haifa and the Northern regions, Highway 5 from the East, and Highway 1 from Jerusalem and the Southeast. The Ayalon Highway is heavily used; on an average day, almost 600,000 vehicles enter the freeway. It consists of a multi-lane highway with a multi-track railway located between the opposite travel lanes. Some of the highway's route is along the Ayalon River, hence its name.
Highway 5 or the Trans-Samaria Highway, is one of Israel's main highways, connecting the Mediterranean coast immediately north of Tel Aviv with the central Sharon plain and eastwards to Ariel and other Israeli settlements in the northern West Bank.
Highway 90 is the longest Israeli road, at about 480 kilometres (300 mi), and stretches from Metula and the northern border with Lebanon, along the western side of the Sea of Galilee, through the Jordan River Valley, along the Dead Sea's western bank, through the Arabah valley, and until Eilat and the southern border with Egypt on the Red Sea. The central section of the road traverses the Israeli-occupied West Bank. While it passes near the city of Jericho, it runs through Area C and does not enter areas controlled by the Palestinian Authority.
Highway 1 is the main highway in Israel, connecting Tel Aviv and Jerusalem, and continuing eastwards to the Jordan Valley in the West Bank.
Highway 50, officially called Begin Boulevard and also referred to as Menachem Begin Expressway or Begin Highway, is a north-south urban freeway, through western Jerusalem, named after Israel's sixth Prime Minister, Menachem Begin. Local Jerusalemites simply refer to it as 'Begin'. It enters Area C of the West Bank on the north end and East Jerusalem on both ends.
Highway 2 is an Israeli highway located on the coastal plain of the Mediterranean Sea. It begins as a major arterial road within Tel Aviv, becoming a freeway as it exits the city northward, continuing to Haifa. North of Tel Aviv, the highway is also called The Coastal Highway.
Route 443 is also known as Ma'ale Beit Horon, following the ancient east-west trade route connecting the Via Maris and the Way of the Patriarchs. It is the main highway connecting Tel Aviv and Gush Dan with Jerusalem via Modi'in. While technically listed as a regional road, it is, for the most part, a divided, four-lane highway which utilizes some grade separation and interchanges, as well as major at-grade intersections, and thus is not classified as a motorway, even though there is a short motorway section on its western end, connecting it to westbound Highway 1.
The Nitzana Border Crossing is an international border crossing between El Ouga in Egypt and Nitzana in Israel. Opened in 1982, the crossing used to handle pedestrians as well as private cars but most of the crossing was being done via the Taba Border Crossing in Eilat and the Rafah Border Crossing in Rafah that the Israelis decided to shut down the crossing to tourists. There is talk of possibly reopening the crossing to tourists now that the Rafah crossing is no longer in Israeli control.
Nitzana is an educational youth village and community settlement in southern Israel. Located in the western Negev desert, adjacent to the Egyptian border, it falls under the jurisdiction of Ramat HaNegev Regional Council. In 2021 it had a population of 408.
Highway 3 is a highway in Israel. It begins at Highway 4 on the outskirts of Ashkelon, running east-northeast, passing through Kiryat Malakhi and Latrun, and ending just short of Modi'in.
Highway 12 is a single carriageway road in the South District of Israel. It surrounds the mountains of Eilat from the north and west, and it connects Eilat to Highway 10 and Highway 40, which lead toward central Israel. Highway 10 continues north toward the Gaza Strip, whereas Highway 40 proceeds to Beersheba via Mizpe Ramon.
Highway 9 is an east-west limited-access expressway in Israel that opened to traffic on July 24, 2014.
Highway 71 is an east-west highway that passes through the eastern Jezreel Valley and the Beit She'an Valley, below the north slopes of the Gilboa mountains, in northern Israel. The road follows a path parallel to the Harod Creek in the Harod Valley and to the Jezreel Valley railway. It is 35 kilometres (22 mi) long and leads from Afula in the west, via Beit She'an, to the Jordan River Border Crossing in the east. The Navot interchange located approximately 10 km southeast of Afula provides a shortcut via Route 675 through the Ta'anakh region from Highway 71 and Beit She'an to Highway 65 and central Israel.
Route 171 is a regional east-west road in southern Israel. It is the only east-west road in the Negev Mountains. It is 33 km long. It goes from Mount Harif junction on Highway 10 adjacent to Israel's border with Egypt to HaRuhot junction with Highway 40 about 5 km north of Mitzpe Ramon. The road passes mostly along the northern edge of Makhtesh Ramon and along the flowing path of Nahal Nitzana. In its eastern portion, it crosses HaRuhot Plain and passes by the Mitzpe Ramon Airport.
Route 899 is an east-west regional highway in the Upper Galilee in northern Israel. For almost its entire length of 63 km, it proceeds parallel to the nearby border between Israel and Lebanon. In Israel, Route 899 is commonly known as the "northern route".
The Netafim Border Crossing was a border crossing between Israel and Egypt. It was located adjacent to Highway 12, about 12 km north of Eilat, 1 km north west of Ein Netafim. As of 2023, the only two working crossing points between Israel and Egypt are the Taba-Eilat Border Crossing and the Nitzana Border Crossing.
Highway 45 is the official designation of a 3.3 km stretch of road forming a continuous connection between Route 443 from the Tel Aviv Metropolitan Area and Highway 50 to central Jerusalem and a 1.4 km spur serving the Atarot Industrial Park.
Route 505 is a regional Israeli highway in the Israeli-occupied West Bank.
Route 227 is a 34-kilometre (21 mi) road in the eastern Negev desert of Israel. It starts from an intersection with Route 206 in the northwest and ends in Ir Ovot in the southeast, intersecting with Highway 90. It has one at-grade intersection at 19 km. The original road was laid by British land surveyors in 1927. Prior to 1956, this was the primary route from Beersheba to Eilat.
Route 204 is a regional road in the Negev, Israel. It starts at the Halukim junction with Highway 40, passes by the town of Yeruham and ends at the Dimona junction on Highway 25, near Dimona.
