The N1 is a national route in South Africa that runs from Cape Town through Bloemfontein, Johannesburg, Pretoria and Polokwane to Beit Bridge on the border with Zimbabwe. It forms the first section of the famed Cape to Cairo Road.
The R44 is a provincial route in Western Cape, South Africa that connects Piketberg with Kleinmond via Wellington, Stellenbosch, Somerset West and Strand. The coastal section between Kleinmond and Gordon's Bay is a very scenic ocean drive. The section between Gordon's Bay and Stellenbosch via Strand and Somerset West is a dual carriageway. The R44 is co-signed with the R46 between Gouda and Hermon in the Berg River valley.
The R45 is a provincial route in Western Cape, South Africa that connects Saldanha with Villiersdorp via Vredenburg, Malmesbury and Paarl. The route is mostly a two-lane wide-shouldered highway, however sections within Paarl and between Vredenburg and Saldanha are dual-carriageways. The R45 is co-signed with the N7 for a short segment north of Malmesbury.
The R56 is a provincial route in South Africa that connects Middelburg with Pietermaritzburg via Molteno, Maclear and Kokstad. It is co-signed with the N2 between Kokstad and Stafford's Post for 39 kilometres.
The R59 is a provincial route in South Africa that connects Hertzogville with Alberton via Bothaville, Parys and Vereeniging. The R59 is a freeway from the R57 Junction in Sasolburg until the N12 Reading Interchange in Alberton, signposted as the Sybrand van Niekerk Freeway.
The R61 is a long provincial route in South Africa that connects Beaufort West with Port Shepstone via Graaff-Reinet, Komani, Mthatha and Port Edward.
The R63 is a tarred provincial route in South Africa that connects Calvinia with Komga via Carnarvon, Victoria West, Graaff-Reinet, Somerset East and King William's Town. It is cosigned with the N10 between Eastpoort and Cookhouse for 24 kilometres.
The R67 is a provincial route in Eastern Cape, South Africa that connects Port Alfred with Komani via Grahamstown.
The R75 is a provincial route in Eastern Cape, South Africa that connects Graaff-Reinet with Gqeberha via Despatch, Kariega and Jansenville.
The R102 is a Regional Route in South Africa. It is the route designation for all old sections of the N2, thus it is a discontinuous road that resumes in areas where a new N2 has been constructed.
The R323 is a Regional Route in South Africa that connects Riversdale in the south with Laingsburg in the north.
The R324 is a Regional Route in South Africa that connects Barrydale to the north with Port Beaufort and Witsand to the south.
The R334 is a Regional Route in the Nelson Mandela Bay Metropolitan Municipality of South Africa that connects the N2 west of Port Elizabeth to the N2 at Coega north of Port Elizabeth via Uitenhage. The middle section of the route is also designated as the M20 metropolitan route.
The R346 is a Regional Route in Eastern Cape, South Africa that connects Kidd's Beach with Stutterheim via King William’s Town.
The R355 is a Regional Route in South Africa that connects the R46 near Ceres with Kleinsee via Calvinia and Springbok.
The N2 is a national route in South Africa that runs from Cape Town through George, Gqeberha, East London, Mthatha, Port Shepstone and Durban to Ermelo. It is the main highway along the Indian Ocean coast of the country. Its current length of 2,255 kilometres (1,401 mi) makes it the longest numbered route in South Africa.
The R618 is a Regional Route in South Africa that connects Hlobane with St Lucia via Nongoma and Mtubatuba.
The M4 is a long metropolitan route in the City of Cape Town Metropolitan Municipality in South Africa. It connects the Cape Town CBD with the Cape of Good Hope via Wynberg, Muizenberg and Fish Hoek. Originally, it was the main route connecting the Cape Town CBD with the Southern Suburbs and is thus named Main Road for much of its length. From the CBD to Kirstenhof, it is parallel to the M3 Freeway.
The M9 is a long metropolitan route in the City of Cape Town, South Africa. It connects Sir Lowry's Pass Village with Wynberg via Somerset West, Firgrove, Macassar, Khayelitsha and Nyanga.
The M10 is a metropolitan route in the City of Cape Town Metropolitan Municipality, South Africa. It connects the town of Bellville with Philippi on the Cape Flats.
R324 
N2 
