Venomous fish

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The most venomous known fish is the reef stonefish. It is an ambush predator which waits camouflaged on the bottom. Reef0915 - Flickr - NOAA Photo Library.jpg
The most venomous known fish is the reef stonefish. It is an ambush predator which waits camouflaged on the bottom.
The beautiful and highly visible lionfish uses venomous barbs around its body as a defence against predators. Lion Fish.JPG
The beautiful and highly visible lionfish uses venomous barbs around its body as a defence against predators.
The stargazer buries itself out of sight. It can deliver electric shocks as well as venom. Uranoscopus sulphureus.jpg
The stargazer buries itself out of sight. It can deliver electric shocks as well as venom.
The stinger of a stingray Stringray's sting.jpg
The stinger of a stingray

Venomous fish are species of fish which produce strong mixtures of toxins harmful to humans (called venom) which they deliberately deliver by means of a bite, sting, or stab, resulting in an envenomation. As a contrast, poisonous fish also produce a strong toxin, but they do not bite, sting, or stab to deliver the toxin, instead being poisonous to eat because the human digestive system does not destroy the toxin they contain in their bodies. [1] Venomous fish do not necessarily cause poisoning if they are eaten, as the digestive system often destroys the venom. [1]

Contents

There are at least 1200 species of venomous fish, [2] [3] with catfishes alone possibly contributing 250–625 species to that total. [4] The former number accounts for two-thirds of the venomous vertebrate population. [5] There are more venomous fish than venomous snakes and indeed more than the combined total of all other venomous vertebrates. [2] Venomous fish are found in almost all habitats around the world, but mostly in tropical waters. Encounters with these species injure over 50,000 people every year. [6]

Venomous fishes carry their venom in venom glands and use various delivery systems, such as spines or sharp fins, barbs, spikes and fangs. The most common venom delivery system is via dorsal spines. [7] Venomous fish tend to be either very visible, using flamboyant colors to discourage predators from attacking them, or skillfully camouflaged and possibly buried in the sand. Apart from the value of improved self defense or capacity to kill prey, venom helps bottom dwelling fish by killing bacteria that could otherwise invade their skin. Few of these venoms have been studied. They are a yet-to-be tapped resource for bioprospecting to find drugs with medical uses. [3]

Examples

Antivenom

Striped poison fang blenny can deliver a quick and painful bite. Striped poison fang blenny - Meiacanthus grammistes.jpg
Striped poison fang blenny can deliver a quick and painful bite.

Venomous fish are very often involved in human injury, usually by accident, but few studies have been done to investigate the constituents of fish venom. Even fewer studies have been done to create antivenom.

The only commercially available antivenom is for the Indo-Pacific stonefish, Synanceja trachynis Stonefish Antivenom (SFAV). [17]

Biological and pharmacological importance of fish venoms

It has been found that the mucous and sting venom of Potamotrygon cf. henlei, a species of stingray that is found in Brazil, is toxic to mice that have nociceptive, edematogenic, and proteolysis activities. Two peptides were isolated from the stingray venom, orpotrin, which causes vasoconstriction, and porflan, which causes inflammation. Knowing how these peptides are structured could lead to the development of a neutralization technique that could effectively act as an antivenom. [18]

Of all the piscine venoms studied, they all produce profound cardiovascular alterations, both in vivo and in vitro. These changes stimulate the release of nitric oxide from the endothelial cells, smooth muscle contractions, and other effects of the atria. Piscine venoms also produce neuromuscular activity effects- depolarization of nerve and muscle cells. In addition, piscine venoms have strong cytolytic activity. In experimental models and in Western immunoblotting analysis, all tested piscine venoms showed structural similarity, which could lead to the advent of an overarching antivenom or other novel uses. [19]

See also

Related Research Articles

<span class="mw-page-title-main">Venom</span> Toxin secreted by an animal

Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved venom apparatus, such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism.

<span class="mw-page-title-main">Stingray</span> Suborder of fishes

Stingrays are a group of sea rays, which are cartilaginous fish related to sharks. They are classified in the suborder Myliobatoidei of the order Myliobatiformes and consist of eight families: Hexatrygonidae, Plesiobatidae, Urolophidae (stingarees), Urotrygonidae, Dasyatidae, Potamotrygonidae, Gymnuridae and Myliobatidae . There are about 220 known stingray species organized into 29 genera.

<span class="mw-page-title-main">Antivenom</span> Medical treatment for venomous bites and stings

Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection.

<span class="mw-page-title-main">Potamotrygonidae</span> Family of cartilaginous fishes

River stingrays or freshwater stingrays are Neotropical freshwater fishes of the family Potamotrygonidae in the order Myliobatiformes, one of the four orders of batoids, cartilaginous fishes related to sharks. They are found in rivers in tropical and subtropical South America. A single marine genus, Styracura, of the tropical West Atlantic and East Pacific are also part of Potamotrygonidae. They are generally brownish, greyish or black, often with a mottled, speckled or spotted pattern, have disc widths ranging from 31 to 200 centimetres (1.0–6.6 ft) and venomous tail stingers. River stingrays feed on a wide range of smaller animals and the females give birth to live young. There are more than 35 species in five genera.

<span class="mw-page-title-main">Venomous snake</span> Species of the suborder Serpentes that produce venom

Venomous snakes are species of the suborder Serpentes that are capable of producing venom, which they use for killing prey, for defense, and to assist with digestion of their prey. The venom is typically delivered by injection using hollow or grooved fangs, although some venomous snakes lack well-developed fangs. Common venomous snakes include the families Elapidae, Viperidae, Atractaspididae, and some of the Colubridae. The toxicity of venom is mainly indicated by murine LD50, while multiple factors are considered to judge the potential danger to humans. Other important factors for risk assessment include the likelihood that a snake will bite, the quantity of venom delivered with the bite, the efficiency of the delivery mechanism, and the location of a bite on the body of the victim. Snake venom may have both neurotoxic and hemotoxic properties. There are about 600 venomous snake species in the world.

<i>Naja</i> Genus of snakes

Naja is a genus of elapid snakes commonly known as cobras. Like all other elapids, it is venomous. Members of the genus Naja are the most widespread and the most widely recognized as "true" cobras. Various species occur in regions throughout Africa, Southwest Asia, South Asia, and Southeast Asia. Several other elapid species are also called "cobras", such as the king cobra and the rinkhals, but neither are true cobras, in that they do not belong to the genus Naja, but instead each belong to monotypic genera Hemachatus and Ophiophagus.

<i>Rhabdophis</i> Genus of snakes

Rhabdophis is a genus of snakes in the subfamily Natricinae of the family Colubridae. Species in the genus Rhabdophis are generally called keelback snakes, and are found primarily in Southeast Asia.

Although most species in the Red Sea pose no threat to humans, there are a few notable exceptions.

<span class="mw-page-title-main">Xingu River ray</span> Species of cartilaginous fish

The Xingu River ray, white-blotched river stingray, or polka-dot stingray is a species of freshwater fish in the family Potamotrygonidae. It is endemic to the Xingu River basin in Brazil and prefers rocky bottoms. It is sometimes kept in aquaria. The Xingu river ray is a venomous stingray that contains venom localized at its dentine spine in its tail. While the ray's venom composition does not change with maturation, the venom toxicity decreases as rays get older. On the other hand, rays’ jaw shape, stiffness, and mineralization are strengthened with age, which allows mature rays the ability to consume hard-shelled invertebrates. These changes in traits with maturation reflect the different pressures rays experience in terms of functions such as feeding and avoiding predation during different maturity stages.

<i>Synanceia</i> Genus of venomous fishes

Synanceia is a genus of ray-finned fish belonging to the subfamily Synanceiinae, the stonefishes, which is classified within the family Scorpaenidae, the scorpionfishes and relatives. Stonefishes are venomous, dangerous, and fatal to humans. They are the most venomous fish known. They are found in the coastal regions of the Indo-Pacific.

<span class="mw-page-title-main">Stingray injury</span> Injury from a stingrays barbed tail

A stingray injury is caused by the venomous tail spines, stingers or dermal denticles of rays in the order Myliobatiformes, most significantly those belonging to the families Dasyatidae, Urotrygonidae, Urolophidae, and Potamotrygonidae. Stingrays generally do not attack aggressively or even actively defend themselves. When threatened, their primary reaction is to swim away. However, when attacked by predators or stepped on, the stinger in their tail is whipped up. This is normally ineffective against sharks, their main predator.

<span class="mw-page-title-main">Coral reef fish</span> Fish which live amongst or in close relation to coral reefs

Coral reef fish are fish which live amongst or in close relation to coral reefs. Coral reefs form complex ecosystems with tremendous biodiversity. Among the myriad inhabitants, the fish stand out as colourful and interesting to watch. Hundreds of species can exist in a small area of a healthy reef, many of them hidden or well camouflaged. Reef fish have developed many ingenious specialisations adapted to survival on the reefs.

<span class="mw-page-title-main">Animal attacks in Australia</span>

Wildlife attacks in Australia occur every year from several different native species, including snakes, spiders, freshwater and saltwater crocodiles, various sharks, cassowaries, kangaroos, stingrays and stonefish and a variety of smaller marine creatures such as bluebottles, blue-ringed octopus, cone shells and jellyfish.

Stonustoxin (SNTX) is an extremely potent cytolytic toxin of the perforin-like superfamily. It is mainly found in stonefish (Synanceia). The name Stonustoxin is an abbreviation of STOnefish National University of Singapore.

Mipartoxin-I is a neurotoxin produced by Micrurus mipartitus, a venomous coral snake distributed in Central and South America. This toxin causes a neuromuscular blockade by blocking the nicotinic acetylcholine receptor. It is the most abundant component in the venom.

The whole blood clotting test is a blood test used to check the coagulation mechanism in the blood following a snake bite. If the test is positive after a bite in South East Asia it indicates the snake was a viper rather than an elapid. It can also be used to assess the effectiveness of antivenin therapy.

<span class="mw-page-title-main">Animal attacks in Latin America</span>

List of reported attacks and species involved in Latin America.

<i>Potamotrygon rex</i> Species of freshwater stingray

Potamotrygon rex, the great river stingray, is a species of freshwater stingray belonging to the family Potamotrygonidae, native to South America in the Neotropical region. P. rex, along with some other Potamotrygon species form a sub-species group known as "black stingrays" known by their similar features and their locality to rivers draining the Central Brazilian Shield. Specifically, it is native to the Rio Tocantins in the central Brazilian state of Tocantins. It is quite a large organism, weighing up to 20 kg. Its appearance is dark brown to blackish with distinct clusters of yellow-orange spots around similarly colored ocelli on its dorsal side. Distinguishing features include broad pelvic-fin apices, lack of labial grooves, irregular double row of dorsal tail thorns, and having two angular cartilages associated with each hyomandibula.

Venomics is the large-scale study of proteins associated with venom. Venom is a toxic substance secreted by animals, which is typically injected either offensively or defensively into prey or aggressors, respectively.

References

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  2. 1 2 Smith WL and Wheeler WC (2006) "Venom Evolution Widespread in Fishes: A Phylogenetic Road Map for the Bioprospecting of Piscine Venoms" Journal of Heredity97 (3):206-217.
  3. 1 2 3 4 5 Grady, Denise Venom Runs Thick in Fish Families, Researchers Learn New York Times 22 August 2006.
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  16. Wilcox, Christie (March 30, 2017). "Beware the blenny's bite: scientists uncover the toxins in fang blenny venom". Discover.
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