Biliverdin reductase A

Last updated
biliverdin reductase A
Bilivra.jpg
Biliverdin reductase A dimer, Human
Identifiers
EC no. 1.3.1.24
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins
BLVRA
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases BLVRA , BLVR, BVR, BVRA, biliverdin reductase A
External IDs OMIM: 109750 MGI: 88170 HomoloGene: 572 GeneCards: BLVRA
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000712
NM_001253823

NM_026678

RefSeq (protein)

NP_000703
NP_001240752

NP_080954

Location (UCSC) Chr 7: 43.76 – 43.81 Mb Chr 2: 126.91 – 126.94 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Biliverdin reductase A is a protein that in humans is encoded by the BLVRA gene. [5] [6]

Contents

Function

The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. [5]

Clinical significance

Mutations in this gene are associated with hyperbiliverdinemia. [5]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000106605 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001999 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 3 "Entrez Gene: Biliverdin reductase A".
  6. Schomburg D, Schomburg I, Chang A (2004). Class 1 Oxidoreductases V. Springer Handbook of Enzymes. Vol. 21 (2nd ed.). Springer Science & Business Media. pp. 140–. ISBN   978-3-540-22515-7.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.