Cornus officinalis

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Cornus officinalis
Cornus officinalis SZ50.png
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Cornales
Family: Cornaceae
Genus: Cornus
Subgenus: Cornus subg. Cornus
Species:
C. officinalis
Binomial name
Cornus officinalis
Torr. ex Dur.
Cornus officinalis5.jpg

Cornus officinalis, the Japanese cornel or Japanese cornelian cherry, [1] is a species of flowering plant in the dogwood family Cornaceae. Despite its name, it is native to China and Korea as well as Japan. [2] It is not to be confused with C. mas , which is also known as the Cornelian cherry. It is not closely related to the true cherries of the genus Prunus .

Contents

Description

It is a large, strongly-growing deciduous shrub with rough flaky bark. Umbels of acid yellow flowers appear in early spring before the oval leaves. The red berries, which are edible, appear later in the summer, and the leaves turn shades of red before falling in the autumn. [3]

Etymology

In Korean it is known as sansuyu (산수유), in Chinese as shān zhū yú (山茱萸) and in Japanese as sanshuyu (さんしゅゆ).

The Latin specific epithet officinalis refers to plants which have some medicinal or culinary use - in this case the edible berries. [4]

Cultivation

The plant is valued in cultivation for providing year-round interest in the garden. It is, however, quite a substantial shrub, typically growing to 8 m (26 ft) tall and broad. The cultivar 'Kintoki', with larger and more abundant flowers, has won the Royal Horticultural Society's Award of Garden Merit. [5] [6]

Herbalism

It occurs in China, Japan and Korea where it is used as a food plant and as a medicinal plant.

Chemical constituents

The plant contains oleanolic acid and ursolic acid. [7] Ursolic acid has shown in vitro protective effects on auditory cells. [8]

Ethanolic extracts of the fruit of C. officinalis has been shown to prevent hepatic injuries associated with acetaminophen-induced liver injury-induced hepatotoxicity (in mice) by preventing or alleviating oxidative stress. [9]

The chemical constituents isolated from the fruit (Corni fructus) have protective effects on beta cells in vitro , [10] [11] and may control postprandial hyperglycemia by alpha-glucosidase inhibition. [12]

Cornel iridoid glycoside, a chemical extracted from Cornus officinalis, promoted neurogenesis and angiogenesis and improved neurological function after ischemia in rats. [13]

Morroniside, the most abundant iridoid glycoside extracted from Cornus officinalis, substantially reduces osteophyte formation and subchondral sclerosis in mice models. Specifically, morroniside significantly promotes cartilage matrix synthesis by increasing collagen type II expression and suppressing chondrocyte pyroptosis. It inhibits matrix metalloproteinase-13 (MMP13), Caspase-1 and nod-like receptor protein-3 (NLRP3) expression in DMM mice and IL-1β-stimulated chondrocytes, and enhances chondrocyte proliferation and inhibits chondrocyte apoptosis. [14] It also slows OA progression by inhibiting nuclear factor-κB (NF-κB) signaling. [15]

A randomized, double-blinded, placebo-controlled study found that a Chinese herbal formula that mainly consisted of Cornus officinalis was not only effective at improving erectile function, but it was also safe for the treatment of erectile dysfunction. [16] A chemical substance isolated from Cornus officinalis also may enhance the motility of human sperm. [17]

Cell cultures of C. officinalis contain gallotannins in the forms of tri-, tetra- and pentagalloylglucoses. The main tannins are 1,2,3,6-tetragalloylglucose, 1,2,6-trigalloyl-glucose, 1,2,3,4,6-pentagalloyl-glucose and 6-digalloyl-1,2,3-trigalloyl-glucose. [18]

Nutrition

Cornelian cherry juices are rich in potassium, calcium, sodium, iron, zinc, manganese, and copper. Compared to other juices obtained from plum, pear, and apple, Cornelian cherry juice contained higher levels of dietary minerals. [19]

Related Research Articles

<i>Cornus</i> Genus of flowering plants in the dogwood family Cornaceae

Cornus is a genus of about 30–60 species of woody plants in the family Cornaceae, commonly known as dogwoods, which can generally be distinguished by their blossoms, berries, and distinctive bark. Most are deciduous trees or shrubs, but a few species are nearly herbaceous perennial subshrubs, and some species are evergreen. Several species have small heads of inconspicuous flowers surrounded by an involucre of large, typically white petal-like bracts, while others have more open clusters of petal-bearing flowers. The various species of dogwood are native throughout much of temperate and boreal Eurasia and North America, with China, Japan, and the southeastern United States being particularly rich in native species.

<i>Lonicera japonica</i> Flowering shrub known as Japanese honeysuckle

Lonicera japonica, known as Japanese honeysuckle and golden-and-silver honeysuckle, is a species of honeysuckle native to eastern Asia, including many parts of China. It is often grown as an ornamental plant, but has become an invasive species in a number of countries. Japanese honeysuckle is used in traditional Chinese medicine.

<i>Hydrangea macrophylla</i> Species of flowering plant in the family Hydrangeaceae

Hydrangea macrophylla is a species of flowering plant in the family Hydrangeaceae, native to China. It is a deciduous shrub growing to 2 m (7 ft) tall by 2.5 m (8 ft) broad with large heads of pink or blue flowers in summer and autumn. Common names include bigleaf hydrangea, French hydrangea, lacecap hydrangea, mophead hydrangea, and hortensia. It is widely cultivated in many parts of the world in many climates. It is not to be confused with H. aspera 'Macrophylla'.

<i>Rosa gallica</i> Species of plant

Rosa gallica, the Gallic rose, French rose, or rose of Provins, is a species of flowering plant in the rose family, native to southern and central Europe eastwards to Turkey and the Caucasus. Rosa gallica was one of the first species of rose to be cultivated in central Europe. It is a parent of several important cultivars.

<i>Junonia coenia</i> Species of insect (butterfly)

Junonia coenia, known as the common buckeye or buckeye, is a butterfly in the family Nymphalidae. Its range covers much of North America and some of Central America, including most of the eastern half of the US, the lower to middle Midwest, the Southwest, southern Canada, and Mexico. Its habitat is open areas with low vegetation and some bare ground. Its original ancestry has been traced to Africa, which then experiences divergence in Asia. The species Junonia grisea, the gray buckeye, is found west of the Rocky Mountains and was formerly a subspecies of Junonia coenia.

<i>Cornus mas</i> Species of flowering plant in the family Cornaceae

Cornus mas, commonly known as cornel, is a species of shrub or small tree in the dogwood family Cornaceae native to Western Europe, Southern Europe, and Southwestern Asia.

<i>Verbena officinalis</i> Species of flowering plant

Verbena officinalis, the common vervain or common verbena, is a perennial herb native to Europe. It grows up to 70 cm high, with an upright habitus. The lobed leaves are toothed, and the delicate spikes hold clusters of two-lipped mauve flowers.

<i>Paeonia lactiflora</i> Species of flowering plant

Paeonia lactiflora is a species of herbaceous perennial flowering plant in the family Paeoniaceae, native to central and eastern Asia from eastern Tibet across northern China to eastern Siberia.

<i>Sanguisorba officinalis</i> Species of flowering plant in the rose family Rosaceae

Sanguisorba officinalis, commonly known as great burnet, is a plant in the family Rosaceae, subfamily Rosoideae. It is native throughout the cooler regions of the Northern Hemisphere in Europe, northern Asia, and northern North America.

<span class="mw-page-title-main">Betulinic acid</span> Chemical compound

Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch from which it gets its name, but also the ber tree, selfheal, the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas, a member of the persimmon family, Tetracera boiviniana, the jambul, flowering quince, rosemary, and Pulsatilla chinensis.

<span class="mw-page-title-main">Ursolic acid</span> Pentacyclic chemical compound found in fruits

Ursolic acid, is a pentacyclic triterpenoid identified in the epicuticular waxes of apples as early as 1920 and widely found in the peels of fruits, as well as in herbs and spices like rosemary and thyme.

<span class="mw-page-title-main">Oleanolic acid</span> Pentacyclic chemical compound in plant leaves and fruit

Oleanolic acid or oleanic acid is a naturally occurring pentacyclic triterpenoid related to betulinic acid. It is widely distributed in food and plants where it exists as a free acid or as an aglycone of triterpenoid saponins.

<span class="mw-page-title-main">Catalpol</span> Chemical compound

Catalpol is an iridoid glucoside. This natural product falls in the class of iridoid glycosides, which are simply monoterpenes with a glucose molecule attached.

<span class="mw-page-title-main">Aucubin</span> Chemical compound

Aucubin is an iridoid glycoside. Iridoids are commonly found in plants and function as defensive compounds. Iridoids decrease the growth rates of many generalist herbivores.

<span class="mw-page-title-main">Deacetylasperulosidic acid</span> Chemical compound

Deacetylasperulosidic acid is an iridoid compound found in a few medicinal plants, such as Morinda citrifolia. Some in vitro and in vivo bioactivities of deacetylasperulosidic acid include anti-inflammatory, analgesic, anti-cancer, antioxidant, anti-arthritic, anti-mutagenic, anti-clastogenic, and hepatoprotection.

<span class="mw-page-title-main">Verbascoside</span> Chemical compound

Verbascoside is a caffeoyl phenylethanoid glycoside in which the phenylpropanoid caffeic acid and the phenylethanoid hydroxytyrosol form an ester and an ether bond respectively, to the rhamnose part of a disaccharide, namely β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-(4-O-caffeoyl)-glucopyranoside.

<span class="mw-page-title-main">Sophoricoside</span> Chemical compound

Sophoricoside is an isoflavone Genistein glycoside found in the dried ripe fruit of Styphnolobium japonicum (L.) Schott, a herb used in traditional Chinese medicine. At the time the chemical was discovered and named the plant was called Sophora japonica L.

Catechin-7-<i>O</i>-glucoside Chemical compound

Catechin-7-O-glucoside is a flavan-3-ol glycoside formed from catechin.

<i>Saururus chinensis</i> Species of flowering plant in the family Saururaceae

Saururus chinensis, commonly known as Asian lizard's tail, is an herb that grows in low, damp places to more than 1 meter high, endemic to China, India, Japan, Korea, Philippines, and Vietnam. Its leaves are green, papery, ribbed, densely glandular, and ovate to ovate-lanceolate, and (4-)10-20 × (2-)5-10 cm in size. Each flower spike resembles a lizard's tail.

<i>Phlomoides tuberosa</i> Species of flowering plant

Phlomoides tuberosa, the sage-leaf mullein, is a perennial herbaceous flowering plant in the family Lamiaceae, native to China, Kazakhstan, Kyrgyzstan, Mongolia, Russia; SW Asia and Europe. Enlarged, tuberous roots give rise to erect stems to 150 cm bearing purple-red flowers.

References

  1. "Cornus officinalis". Germplasm Resources Information Network . Agricultural Research Service, United States Department of Agriculture.
  2. "Cornus officinalis". Flora of China via eFloras.org, Missouri Botanical Garden, St. Louis, MO & Harvard University Herbaria, Cambridge, MA.
  3. "Cornus officinalis". www.rhs.org. Royal Horticultural Society. Retrieved 8 February 2020.
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  5. "Cornus officinalis 'Kintoki'". www.rhs.org. Royal Horticultural Society. Retrieved 8 February 2020.
  6. "AGM Plants - Ornamental" (PDF). www.rhs.org. Royal Horticultural Society. July 2017. p. 107. Retrieved 8 February 2020.
  7. Wang, R; Wang, SM; Liang, SW; Xu, GW; Weng, QF (August 2007). "胶束电动毛细管色谱法分离分析山茱萸中齐墩果酸和熊果酸" [Separation and determination of oleanolic acid and ursolic acid from Cornus officinalis by capillary electrophoresis]. Journal of Chinese Medicinal Materials (in Chinese). 30 (8): 946–50. PMID   18074841.
  8. Yu, Hyeon-Hee; Hur, Jong-Moon; Seo, Se-Jeong; Moon, Hae-Dalma; Kim, Hyun-Jin; Park, Rae-Kil; You, Yong-Ouk (January 2009). "Protective Effect of Ursolic Acid from Cornus officinalis on the Hydrogen Peroxide-Induced Damage of HEI-OC1 Auditory Cells". The American Journal of Chinese Medicine. 37 (4): 735–746. doi:10.1142/S0192415X0900720X. PMID   19655411.
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