Egg cell

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Egg cell
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A human egg cell with surrounding corona radiata
Details
Identifiers
Latin ovum
Greek Ωάριο (oário)
MeSH D010063
FMA 67343
Anatomical terms of microanatomy
Human egg cell Ovum Diagram.svg
Human egg cell

The egg cell or ovum (pl.: ova) is the female reproductive cell, or gamete, [1] in most anisogamous organisms (organisms that reproduce sexually with a larger, female gamete and a smaller, male one). The term is used when the female gamete is not capable of movement (non-motile). If the male gamete (sperm) is capable of movement, the type of sexual reproduction is also classified as oogamous. A nonmotile female gamete formed in the oogonium of some algae, fungi, oomycetes, or bryophytes is an oosphere. [2] When fertilized, the oosphere becomes the oospore.[ clarification needed ]

Contents

When egg and sperm fuse during fertilisation, a diploid cell (the zygote) is formed, which rapidly grows into a new organism.

History

While the non-mammalian animal egg was obvious, the doctrine ex ovo omne vivum ("every living [animal comes from] an egg"), associated with William Harvey (1578–1657), was a rejection of spontaneous generation and preformationism as well as a bold assumption that mammals also reproduced via eggs. Karl Ernst von Baer discovered the mammalian ovum in 1827. [3] [4] The fusion of spermatozoa with ova (of a starfish) was observed by Oskar Hertwig in 1876. [5] [6]

Animals

In animals, egg cells are also known as ova (singular ovum, from the Latin word ovum meaning 'egg'). [7] The term ovule in animals is used for the young ovum of an animal. In vertebrates, ova are produced by female gonads (sex glands) called ovaries. A number of ova are present at birth in mammals and mature via oogenesis.

Studies performed on humans, dogs, and cats in the 1870s suggested that the production of oocytes (immature egg cells) stops at or shortly after birth. A review of reports from 1900 to 1950 by zoologist Solomon Zuckerman cemented the belief that females have a finite number of oocytes that are formed before they are born. This dogma has been challenged by a number of studies since 2004. Several studies suggest that ovarian stem cells exist within the mammalian ovary. Whether or not mature mammals can actually create new egg cells remains uncertain and is an ongoing research question. [8] [9]

Mammals including humans

Diagram of a human egg cell Human egg cell.svg
Diagram of a human egg cell
Ovum and sperm fusing together Sperm-egg.jpg
Ovum and sperm fusing together
The process of fertilizing an ovum (top to bottom). Acrosome reaction diagram en.svg
The process of fertilizing an ovum (top to bottom).

In all mammals except monotremes, the ovum is fertilized inside the female body.

The human ova grow from primitive germ cells that are embedded in the substance of the ovaries. Each of them divides repeatedly to give secretions of the uterine glands, ultimately forming a blastocyst. [10]

The ovum is one of the largest cells in the human body, typically visible to the naked eye without the aid of a microscope or other magnification device. [11] The human ovum measures approximately 120 μm (0.0047 in) in diameter. [12]

Ooplasm

Ooplasm is like the yolk of the ovum, a cell substance at its center, which contains its nucleus, named the germinal vesicle, and the nucleolus, called the germinal disc. [13]

The ooplasm consists of the cytoplasm of the ordinary animal cell with its spongioplasm and hyaloplasm, often called the formative yolk; and the nutritive yolk or deutoplasm, made of rounded granules of fatty and albuminoid substances imbedded in the cytoplasm. [13]

Mammalian ova contain only a tiny amount of the nutritive yolk, for nourishing the embryo in the early stages of its development only. In contrast, bird eggs contain enough to supply the chick with nutriment throughout the whole period of incubation. [13]

Ova development in oviparous animals

In the oviparous animals (all birds, most fish, amphibians and reptiles), the ova develop protective layers and pass through the oviduct to the outside of the body. They are fertilized by male sperm either inside the female body (as in birds), or outside (as in many fish). After fertilization, an embryo develops, nourished by nutrients contained in the egg. It then hatches from the egg, outside the mother's body. See egg for a discussion of eggs of oviparous animals.

The egg cell's cytoplasm and mitochondria are the sole means the egg can reproduce by mitosis and eventually form a blastocyst after fertilization.

Ovoviviparity

There is an intermediate form, the ovoviviparous animals: the embryo develops within and is nourished by an egg as in the oviparous case, but then it hatches inside the mother's body shortly before birth, or just after the egg leaves the mother's body. Some fish, reptiles and many invertebrates use this technique.

Plants

Nearly all land plants have alternating diploid and haploid generations. Gametes are produced by the gametophyte, which is the haploid generation. The female gametophyte produces structures called archegonia, and the egg cells form within them via mitosis. The typical bryophyte archegonium consists of a long neck with a wider base containing the egg cell. Upon maturation, the neck opens to allow sperm cells to swim into the archegonium and fertilize the egg. The resulting zygote then gives rise to an embryo, which will grow into a new diploid individual (sporophyte). In seed plants, a structure called the ovule contains the female gametophyte. The gametophyte produces an egg cell. After fertilization, the ovule develops into a seed containing the embryo. [14]

In flowering plants, the female gametophyte (sometimes referred to as the embryo sac) has been reduced to just eight cells inside the ovule. The gametophyte cell closest to the micropyle opening of the ovule develops into the egg cell. Upon pollination, a pollen tube delivers sperm into the gametophyte and one sperm nucleus fuses with the egg nucleus. The resulting zygote develops into an embryo inside the ovule. The ovule, in turn, develops into a seed and in many cases, the plant ovary develops into a fruit to facilitate the dispersal of the seeds. Upon germination, the embryo grows into a seedling. [14]

Gene expression pattern determined by histochemical GUS assays in Physcomitrella patens. The Polycomb gene FIE is expressed (blue) in unfertilized egg cells of the moss Physcomitrella patens (right) and expression ceases after fertilization in the developing diploid sporophyte (left). In situ GUS staining of two female sex organs (archegonia) of a transgenic plant expressing a translational fusion of FIE-uidA under control of the native FIE promoter DEV035048A.jpg
Gene expression pattern determined by histochemical GUS assays in Physcomitrella patens . The Polycomb gene FIE is expressed (blue) in unfertilized egg cells of the moss Physcomitrella patens (right) and expression ceases after fertilization in the developing diploid sporophyte (left). In situ GUS staining of two female sex organs (archegonia) of a transgenic plant expressing a translational fusion of FIE-uidA under control of the native FIE promoter

In the moss Physcomitrella patens, the Polycomb protein FIE is expressed in the unfertilised egg cell (Figure, right) as the blue colour after GUS staining reveals. Soon after fertilisation the FIE gene is inactivated (the blue colour is no longer visible, left) in the young embryo. [15]

Other organisms

In algae, the egg cell is often called oosphere.[ citation needed ]Drosophila oocytes develop in individual egg chambers that are supported by nurse cells and surrounded by somatic follicle cells. The nurse cells are large polyploid cells that synthesize and transfer RNA, proteins, and organelles to the oocytes. This transfer is followed by the programmed cell death (apoptosis) of the nurse cells. During oogenesis, 15 nurse cells die for every oocyte that is produced. [16] In addition to this developmentally regulated cell death, egg cells may also undergo apoptosis in response to starvation and other insults. [16]

See also

Related Research Articles

<span class="mw-page-title-main">Gamete</span> A haploid sex cell

A gamete is a haploid cell that fuses with another haploid cell during fertilization in organisms that reproduce sexually. Gametes are an organism's reproductive cells, also referred to as sex cells. The name gamete was introduced by the German cytologist Eduard Strasburger.

<span class="mw-page-title-main">Gametophyte</span> Haploid stage in the life cycle of plants and algae

A gametophyte is one of the two alternating multicellular phases in the life cycles of plants and algae. It is a haploid multicellular organism that develops from a haploid spore that has one set of chromosomes. The gametophyte is the sexual phase in the life cycle of plants and algae. It develops sex organs that produce gametes, haploid sex cells that participate in fertilization to form a diploid zygote which has a double set of chromosomes. Cell division of the zygote results in a new diploid multicellular organism, the second stage in the life cycle known as the sporophyte. The sporophyte can produce haploid spores by meiosis that on germination produce a new generation of gametophytes.

<span class="mw-page-title-main">Zygote</span> Diploid eukaryotic cell formed by fertilization between two gametes

A zygote is a eukaryotic cell formed by a fertilization event between two gametes. The zygote's genome is a combination of the DNA in each gamete, and contains all of the genetic information of a new individual organism. The sexual fusion of haploid cells is called karyogamy, the result of which is the formation of a diploid cell called the zygote or zygospore.

<span class="mw-page-title-main">Fertilisation</span> Union of gametes of opposite sexes during the process of sexual reproduction to form a zygote

Fertilisation or fertilization, also known as generative fertilisation, syngamy and impregnation, is the fusion of gametes to give rise to a zygote and initiate its development into a new individual organism or offspring. While processes such as insemination or pollination, which happen before the fusion of gametes, are also sometimes informally referred to as fertilisation, these are technically separate processes. The cycle of fertilisation and development of new individuals is called sexual reproduction. During double fertilisation in angiosperms, the haploid male gamete combines with two haploid polar nuclei to form a triploid primary endosperm nucleus by the process of vegetative fertilisation.

<span class="mw-page-title-main">Alternation of generations</span> Reproductive cycle of plants and algae

Alternation of generations is the predominant type of life cycle in plants and algae. In plants both phases are multicellular: the haploid sexual phase – the gametophyte – alternates with a diploid asexual phase – the sporophyte.

<span class="mw-page-title-main">Archegonium</span> Organ of the gametophyte of certain plants, producing and containing the ovum

An archegonium, from the Ancient Greek ἀρχή ("beginning") and γόνος ("offspring"), is a multicellular structure or organ of the gametophyte phase of certain plants, producing and containing the ovum or female gamete. The corresponding male organ is called the antheridium. The archegonium has a long neck canal or venter and a swollen base. Archegonia are typically located on the surface of the plant thallus, although in the hornworts they are embedded.

<span class="mw-page-title-main">Gametogenesis</span> Biological process

Gametogenesis is a biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes. Depending on the biological life cycle of the organism, gametogenesis occurs by meiotic division of diploid gametocytes into various gametes, or by mitosis. For example, plants produce gametes through mitosis in gametophytes. The gametophytes grow from haploid spores after sporic meiosis. The existence of a multicellular, haploid phase in the life cycle between meiosis and gametogenesis is also referred to as alternation of generations.

<span class="mw-page-title-main">Germ cell</span> Gamete-producing cell

A germ cell is any cell that gives rise to the gametes of an organism that reproduces sexually. In many animals, the germ cells originate in the primitive streak and migrate via the gut of an embryo to the developing gonads. There, they undergo meiosis, followed by cellular differentiation into mature gametes, either eggs or sperm. Unlike animals, plants do not have germ cells designated in early development. Instead, germ cells can arise from somatic cells in the adult, such as the floral meristem of flowering plants.

<span class="mw-page-title-main">Sporophyte</span> Diploid multicellular stage in the life cycle of a plant or alga

A sporophyte is the diploid multicellular stage in the life cycle of a plant or alga which produces asexual spores. This stage alternates with a multicellular haploid gametophyte phase.

<span class="mw-page-title-main">Egg</span> Organic vessel in which an embryo first begins to develop

An egg is an organic vessel grown by an animal to carry a possibly fertilized egg cell and to incubate from it an embryo within the egg until the embryo has become an animal fetus that can survive on its own, at which point the animal hatches.

<span class="mw-page-title-main">Ovule</span> Female plant reproductive structure

In seed plants, the ovule is the structure that gives rise to and contains the female reproductive cells. It consists of three parts: the integument, forming its outer layer, the nucellus, and the female gametophyte in its center. The female gametophyte — specifically termed a megagametophyte— is also called the embryo sac in angiosperms. The megagametophyte produces an egg cell for the purpose of fertilization. The ovule is a small structure present in the ovary. It is attached to the placenta by a stalk called a funicle. The funicle provides nourishment to the ovule.On the basis of the relative position of micropyle, body of the ovule, chalaza and funicle, there are six types of ovules . (a) Orthotropous ovule - the micropyle, chalaza and funicle all lie in the same straight line, this is the most primitive type of ovule . Eg: Piper, polygonum and cycas.

<span class="mw-page-title-main">Endosperm</span> Starchy tissue inside cereals and alike

The endosperm is a tissue produced inside the seeds of most of the flowering plants following double fertilization. It is triploid in most species, which may be auxin-driven. It surrounds the embryo and provides nutrition in the form of starch, though it can also contain oils and protein. This can make endosperm a source of nutrition in animal diet. For example, wheat endosperm is ground into flour for bread, while barley endosperm is the main source of sugars for beer production. Other examples of endosperm that forms the bulk of the edible portion are coconut "meat" and coconut "water", and corn. Some plants, such as orchids, lack endosperm in their seeds.

<span class="mw-page-title-main">Human reproductive system</span> Organs involved in reproduction

The human reproductive system includes the male reproductive system which functions to produce and deposit sperm; and the female reproductive system which functions to produce egg cells, and to protect and nourish the fetus until birth. Humans have a high level of sexual differentiation. In addition to differences in nearly every reproductive organ, there are numerous differences in typical secondary sex characteristics.

<span class="mw-page-title-main">Oviparity</span> Animals that lay their eggs, with little or no other embryonic development within the mother

Oviparous animals are animals that reproduce by depositing fertilized zygotes outside the body in metabolically independent incubation organs known as eggs, which nurture the embryo into moving offsprings known as hatchlings with little or no embryonic development within the mother. This is the reproductive method used by most animal species, as opposed to viviparous animals that develop the embryos internally and metabolically dependent on the maternal circulation, until the mother gives birth to live juveniles.

An oogonium is a small diploid cell which, upon maturation, forms a primordial follicle in a female fetus or the female gametangium of certain thallophytes.

<span class="mw-page-title-main">Human fertilization</span> Union of a human egg and sperm

Human fertilization is the union of an egg and sperm, occurring primarily in the ampulla of the fallopian tube. The result of this union leads to the production of a fertilized egg called a zygote, initiating embryonic development. Scientists discovered the dynamics of human fertilization in the 19th century.

<span class="mw-page-title-main">Polar body</span> Byproduct of oogenesis

A polar body is a small haploid cell that is formed at the same time as an egg cell during oogenesis, but generally does not have the ability to be fertilized. It is named from its polar position in the egg.

<span class="mw-page-title-main">Double fertilization</span> Complex fertilization mechanism of flowering plants

Double fertilization or Double fertilisation is a complex fertilization mechanism of flowering plants (angiosperms). This process involves the joining of a female gametophyte with two male gametes (sperm). It begins when a pollen grain adheres to the stigma of the carpel, the female reproductive structure of a flower. The pollen grain then takes in moisture and begins to germinate, forming a pollen tube that extends down toward the ovary through the style. The tip of the pollen tube then enters the ovary and penetrates through the micropyle opening in the ovule. The pollen tube proceeds to release the two sperm in the embryo sacs.

Plant reproduction is the production of new offspring in plants, which can be accomplished by sexual or asexual reproduction. Sexual reproduction produces offspring by the fusion of gametes, resulting in offspring genetically different from either parent. Asexual reproduction produces new individuals without the fusion of gametes, resulting in clonal plants that are genetically identical to the parent plant and each other, unless mutations occur.

<span class="mw-page-title-main">Sexual reproduction</span> Biological process

Sexual reproduction is a type of reproduction that involves a complex life cycle in which a gamete with a single set of chromosomes combines with another gamete to produce a zygote that develops into an organism composed of cells with two sets of chromosomes (diploid). This is typical in animals, though the number of chromosome sets and how that number changes in sexual reproduction varies, especially among plants, fungi, and other eukaryotes.

References

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  15. Mosquna, Assaf; Katz, Aviva; Decker, Eva L.; Rensing, Stefan A.; Reski, Ralf; Ohad, Nir (2009). "Regulation of stem cell maintenance by the Polycomb protein FIE has been conserved during land plant evolution". Development. 136 (14): 2433–2444. doi: 10.1242/dev.035048 . PMID   19542356.
  16. 1 2 McCall K (October 2004). "Eggs over easy: cell death in the Drosophila ovary". Dev. Biol. 274 (1): 3–14. doi:10.1016/j.ydbio.2004.07.017. PMID   15355784.