Insemination is the introduction of sperm (semen) into a female or hermaphrodite's reproductive system in order to fertilize the ovum through sexual reproduction. [1] [2] The sperm enters into the uterus of a mammal or the oviduct of an oviparous (egg-laying) animal. Female humans and other mammals are inseminated during sexual intercourse or copulation, but can also be inseminated by artificial insemination.
In humans, the act and form of insemination has legal, moral and interpersonal implications. However, whether insemination takes place naturally or by artificial means, the pregnancy and the progress of it will be the same. Insemination may be called in vivo fertilisation (from in vivo meaning "within the living") because an egg is fertilized inside the body, this is in contrast with in vitro fertilisation (IVF).
In plants, the fertilization process is referred to as pollination. It is the process of transfer of pollen grains from one anther to the stigma of other plants.
Insemination during sexual intercourse through penile-vaginal penetration is referred to as "natural insemination" (i.e., insemination by natural means). [3] [4] If an artificial lubricant needs to be used, care must be taken that it does not have spermicidal properties. [5] During ejaculation, semen, containing male gametes known as sperm, is expelled from the penis through the male urethra into the moist and warm environment of the female reproductive tract. In humans, semen is usually ejaculated into the posterior vaginal fornix in direct contact with cervical mucus, [6] though sperm may swim from other areas of the vagina or vulva to the cervix. The average volume of semen produced at ejaculation is 2 to 5ml (about 1 teaspoon), [7] containing an average of 182 million sperm. [4] Only a small proportion of the sperm in each ejaculation reach the site of fertilization in the fallopian tubes, their numbers decreasing exponentially as they progress through the female reproductive tract. The majority of sperm either die in the acidic environment of the vagina or drip out with the semen. [4] Prior to ovulation, the cervical mucus becomes thinner and more hospitable to sperm. Sperm swim rapidly into the uterus upon encountering cervical mucus, though many become lost in the cervical crypts where they either die or are delayed. [6] Further attrition occurs in the uterus, where sperm are attacked by the female immune system. Only about 100-1000 sperm reach the fallopian tubes, [8] where they may survive for up to 6 days. [4] If ovulation occurs and the sperm encounter an ovum in the fallopian tube, fertilization may occur.
A woman may also be naturally inseminated while having penile-vaginal intercourse for pleasure without any intent to conceive. This may be unintentional as a result of the failure of a barrier or behavioural method of contraception, or may be intentional if relying on female contraceptive methods or indifferent to the possibility of pregnancy. [4] In most cultures, insemination by a male through sexual intercourse, whether the woman's husband, normal sex partner or not, is subject to social and sexual inhibitions and taboos, and has legal, moral and interpersonal implications. [9]
The term is also used in the context of third-party insemination, where a male who is not the woman's usual sexual partner (i.e., a sperm donor) fathers a child for the woman by providing his sperm through sexual intercourse rather than by providing his sperm for it to be used to produce a pregnancy in the woman by artificial means. [10] The incidence of natural insemination by a sperm donor is usually a private matter, and may also carry greater health risks than where sperm has been processed by a fertility center. Advocates claim natural insemination generates higher pregnancy rates and a more 'natural' conception which does not involve the intervention and intrusion of third parties. However, it has not been medically proven that natural insemination has an increased chance of pregnancy. [11] Additionally, conceiving through natural insemination is considered a natural process, so the father may be liable for child support and have custody and other rights of the child. [11] The law usually draws a distinction between a man fathering a child by natural means, and a man who provides his sperm for it to be used to father a child by artificial means (i.e. by artificial insemination).
Artificial insemination is the introduction of sperm into the reproductive tract of a female by means other than sexual intercourse for the purpose of impregnating the female. [12] In humans, artificial insemination may be used when a woman or her normal sex partner cannot, for any of a number of reasons, conceive by natural means. A number of artificial insemination strategies are available, including intracervical insemination (ICI) and intrauterine insemination (IUI). Compared with natural insemination, artificial insemination may be more invasive, and may require professional assistance and medical expertise, which will have a higher cost. [13]
ICI attempts to simulate natural insemination, without the sexual element. It is painless and is the simplest, easiest and most common method of artificial insemination; it can be performed in the home, either by the female on herself or with non-professional assistance. ICI involves the introduction of unwashed or raw semen into the vagina at the entrance to the cervix, usually by means of a needleless syringe.
The sperm for insemination may be provided either by a sexual partner of the female's choice or by a sperm donor. [14] Donor sperm is most commonly used by lesbian couples and single women, [15] and by heterosexual couples when the male partner is suffering from male infertility. [16] In some circumstances, sperm has been collected from males before they go off to war, or even right after they have died, and used to inseminate their female partners. [17] In some countries, there are laws restricting and regulating who can donate sperm, who can receive artificial insemination, and what the legal consequences are of such insemination. Subject to any such restrictions, donor sperm is available to all women who want or need it. Women who live in a jurisdiction that prohibits them from being artificially inseminated may sometimes choose to obtain it by traveling to a jurisdiction that permits it.
Artificial insemination has been and continues to be commonly used in livestock breeding as an efficient way of increasing production. [18]
In various other animal species, sperm can be introduced into the female's reproductive tract by various means. For example, in some species of hemiptera sperm can be introduced violently by traumatic insemination, [2] parenteral injection through the body wall. In some species of animals, sperm finds its way through the body wall when the spermatophore is left in contact with the female's skin, such as in the onychophora (velvet worms).
Sexual intercourse is a sexual activity typically involving the insertion and thrusting of the male penis inside the female vagina for sexual pleasure, reproduction, or both. This is also known as vaginal intercourse or vaginal sex. Sexual penetration has been known by humans since the dawn of time, and has been an instinctive form of sexual behaviour and psychology among humans. Other forms of penetrative sexual intercourse include anal sex, oral sex, fingering and penetration by use of a dildo, and vibrators. These activities involve physical intimacy between two or more people and are usually used among humans solely for physical or emotional pleasure. They can contribute to human bonding.
Infertility is the inability of a couple to reproduce by natural means. It is usually not the natural state of a healthy adult. Exceptions include children who have not undergone puberty, which is the body's start of reproductive capacity. It is also a normal state in women after menopause.
Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse. It is a fertility treatment for humans, and is a common practice in animal breeding, including dairy cattle and pigs.
The human female reproductive system is made up of the internal and external sex organs that function in the reproduction of new offspring. The reproductive system is immature at birth and develops at puberty to be able to release matured ova from the ovaries, facilitate their fertilization, and create a protective environment for the developing fetus during pregnancy. The female reproductive tract is made of several connected internal sex organs—the vagina, uterus, and fallopian tubes—and is prone to infections. The vagina allows for sexual intercourse, and is connected to the uterus at the cervix. The uterus accommodates the embryo by developing the uterine lining.
Third-party reproduction or donor-assisted reproduction is any human reproduction in which DNA or gestation is provided by a third party or donor other than the one or two parents who will raise the resulting child. This goes beyond the traditional father–mother model, and the third party's involvement is limited to the reproductive process and does not extend into the raising of the child. Third-party reproduction is used by couples unable to reproduce by traditional means, by same-sex couples, and by men and women without a partner. Where donor gametes are provided by a donor, the donor will be a biological parent of the resulting child, but in third party reproduction, he or she will not be the caring parent.
A sperm bank, semen bank, or cryobank is a facility or enterprise which purchases, stores and sells human semen. The semen is produced and sold by men who are known as sperm donors. The sperm is purchased by or for other persons for the purpose of achieving a pregnancy or pregnancies other than by a sexual partner. Sperm sold by a sperm donor is known as donor sperm.
The human reproductive system includes the male reproductive system, which functions to produce and deposit sperm, and the female reproductive system, which functions to produce egg cells and to protect and nourish the fetus until birth. Humans have a high level of sexual differentiation. In addition to differences in nearly every reproductive organ, there are numerous differences in typical secondary sex characteristics.
Human reproduction is sexual reproduction that results in human fertilization to produce a human offspring. It typically involves sexual intercourse between a sexually mature human male and female. During sexual intercourse, the interaction between the male and female reproductive systems results in fertilization of the ovum by the sperm to form a zygote. While normal cells contain 46 chromosomes, gamete cells only contain 23 single chromosomes, and it is when these two cells merge into one zygote cell that genetic recombination occurs and the new zygote contains 23 chromosomes from each parent, giving it 46 chromosomes. The zygote then undergoes a defined development process that is known as human embryogenesis, and this starts the typical 9-month gestation period that is followed by childbirth. The fertilization of the ovum may be achieved by artificial insemination methods, which do not involve sexual intercourse. Assisted reproductive technology also exists.
Reproductive medicine is a branch of medicine concerning the male and female reproductive systems. It encompasses a variety of reproductive conditions, their prevention and assessment, as well as their subsequent treatment and prognosis.
Fertility clinics are medical clinics that assist couples, and sometimes individuals, who want to become parents but for medical reasons have been unable to achieve this goal via the natural course. Clinics apply a number of diagnosis tests and sometimes very advanced medical treatments to achieve conceptions and pregnancies.
Semen quality is a measure of male fertility, a measure of the ability of sperm in semen to accomplish fertilization. Semen quality involves both sperm quantity and quality. Semen quality is a major factor for fertility.
Semen, also known as seminal fluid, is a bodily fluid that contains spermatozoa. Spermatozoa are secreted by the male gonads and other sexual organs of male or hermaphroditic animals and can fertilize the female ovum. In placental mammals, semen also contains secretions from the male accessory glands and is discharged from the penis through the urethral orifice during ejaculation. In humans, seminal fluid contains several components besides spermatozoa: proteolytic and other enzymes as well as fructose are elements of seminal fluid which promote the survival of spermatozoa and provide a medium through which they can move or "swim". The fluid is adapted to be discharged deep into the vagina, so the spermatozoa can pass into the uterus and form a zygote with an egg.
Pregnancy rate is the success rate for getting pregnant. It is the percentage of all attempts that leads to pregnancy, with attempts generally referring to menstrual cycles where insemination or any artificial equivalent is used, which may be simple artificial insemination (AI) or AI with additional in vitro fertilization (IVF).
A conception device is a medical device which is used to assist in the achievement of a pregnancy, often, but not always, by means other than sexual intercourse. This article deals exclusively with conception devices for human reproduction.
Sperm donation is the provision by a man of his sperm with the intention that it be used in the artificial insemination or other "fertility treatment" of one or more women who are not his sexual partners in order that they may become pregnant by him. Where pregnancies go to full term, the sperm donor will be the biological father of every baby born from his donations. The man is known as a sperm donor and the sperm he provides is known as "donor sperm" because the intention is that the man will give up all legal rights to any child produced from his sperm, and will not be the legal father. Sperm donation may also be known as "semen donation".
Religious response to assisted reproductive technology deals with the new challenges for traditional social and religious communities raised by modern assisted reproductive technology. Because many religious communities have strong opinions and religious legislation regarding marriage, sex and reproduction, modern fertility technology has forced religions to respond.
Unexplained infertility is infertility that is idiopathic in the sense that its cause remains unknown even after an infertility work-up, usually including semen analysis in the man and assessment of ovulation and fallopian tubes in the woman. It is usually an exercise in excluding all possible causes before making a diagnosis, however the age of the female partner as well as the duration of infertility are often the most scrutinized characteristics of any infertility case.
Fertility testing is the process by which fertility is assessed, both generally and also to find the "fertile window" in the menstrual cycle. General health affects fertility, and STI testing is an important related field.
Antisperm antibodies (ASA) are antibodies produced against sperm antigens.
Lesbian, gay, bisexual, and transgender people people wishing to have children may use assisted reproductive technology. In recent decades, developmental biologists have been researching and developing techniques to facilitate same-sex reproduction.
Natural insemination has not been recognised in any state as a legal contract, and is still viewed as a natural procreation process where the sperm donor, or the biological father in this case, is still liable for care and support of the child. That means that unlike artificial insemination, a woman pregnant through natural insemination has a legal right to claim child support from the donor and the donor has a legal right to the custody of the child.
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