Pre-ejaculate (also known as pre-ejaculatory fluid, pre-seminal fluid or Cowper's fluid, and colloquially as pre-cum) is a clear, colorless, viscous fluid that is emitted from the urethra of the penis during sexual arousal and in general during sexual activity. It is similar in composition to semen but has distinct chemical differences. The presence of sperm in the fluid is variable from low to absent. Pre-ejaculate functions as a lubricant and an acid neutralizer.
The fluid is discharged from the urethra of the penis during arousal, masturbation, foreplay or at an early stage during sexual intercourse, some time before the individual fully reaches orgasm and semen is ejaculated. It is primarily produced by the bulbourethral glands (Cowper's glands), with the glands of Littré (the mucus-secreting urethral glands) also contributing. [1] [2] The amount of fluid that is issued varies widely among individuals. Some individuals do not produce any pre-ejaculate fluid, [3] while others emit as much as 5 ml (0.18 imp fl oz; 0.17 US fl oz). [1] [4]
Pre-ejaculate fluid contains chemicals associated with semen, such as acid phosphatase, but other semen markers, such as gamma-glutamyltransferase, are absent. [5]
Pre-ejaculate neutralizes acidity in the urethra caused by residual urine, creating a more favorable environment for the passage of sperm. [2] The vagina is normally acidic, so the deposit of pre-ejaculate before the emission of semen may change the vaginal environment to promote sperm survival. [1] Pre-ejaculate also acts as a lubricant during sexual activity, [1] and plays a role in semen coagulation. [1]
Low levels or no sperm exists in pre-ejaculate, although studies examined small samples of men. [4] [6] Two contrary studies found mixed evidence, including individual cases of a high sperm concentration. [7] [8] There is evidence – dating to a 1966 Masters and Johnson study [9] – that pre-ejaculate may contain sperm that can cause pregnancy, which is a common basis of argument against the use of coitus interruptus (withdrawal) as a contraceptive method. [4] [6]
Studies have demonstrated the presence of HIV in most pre-ejaculate samples from infected men. [6] [10] [11]
In rare cases, an individual may produce an excessive amount of pre-ejaculate fluid, which may be treatable by a 5-alpha-reductase inhibitor, such as finasteride. [1]
Coitus interruptus, also known as withdrawal, pulling out or the pull-out method, is an act of birth control during penetrative sexual intercourse, whereby the penis is withdrawn from a vagina prior to ejaculation so that the ejaculate (semen) may be directed away in an effort to avoid insemination.
Safe sex is sexual activity using methods or contraceptive devices to reduce the risk of transmitting or acquiring sexually transmitted infections (STIs), especially HIV. "Safe sex" is also sometimes referred to as safer sex or protected sex to indicate that some safe sex practices do not eliminate STI risks. It is also sometimes used colloquially to describe methods aimed at preventing pregnancy that may or may not also lower STI risks.
The urethra is the tube that connects the urinary bladder to the urinary meatus, through which placental mammals urinate and ejaculate. In non-mammalian vertebrates, the urethra also transports semen but is separate from the urinary tract.
The prostate is an accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation. It is found in all male mammals. It differs between species anatomically, chemically, and physiologically. Anatomically, the prostate is found below the bladder, with the urethra passing through it. It is described in gross anatomy as consisting of lobes and in microanatomy by zone. It is surrounded by an elastic, fibromuscular capsule and contains glandular tissue, as well as connective tissue.
In female human anatomy, Skene's glands or the Skene glands are two glands located towards the lower end of the urethra. The glands are surrounded by tissue that swells with blood during sexual arousal, and secrete a fluid, carried by the Skene's ducts to openings near the urethral meatus, particularly during orgasm.
Female ejaculation is characterized as an expulsion of fluid from the Skene's gland at the lower end of the urethra during or before an orgasm. It is also known colloquially as squirting or gushing, although research indicates that female ejaculation and squirting are different phenomena, squirting being attributed to a sudden expulsion of liquid that partly comes from the bladder and contains urine.
The bulbourethral glands or Cowper's glands are two small exocrine and accessory glands in the reproductive system of many male mammals. They are homologous to Bartholin's glands in females. The bulbourethral glands are responsible for producing a pre-ejaculate fluid called Cowper's fluid, which is secreted during sexual arousal, neutralizing the acidity of the urethra in preparation for the passage of sperm cells. The paired glands are found adjacent to the urethra just below the prostate, seen best by screening (medicine) MRI as a tool in preventative healthcare in males. Screening MRI may be performed when there is a positive prostate-specific antigen on basic laboratory tests. Prostate cancer is the second-most common cause of cancer-related mortality in males in the USA.
Coitus reservatus, also known as sexual continence, is a form of sexual intercourse in which a male does not attempt to ejaculate within his partner, avoiding the seminal emission. It is distinct from death-grip syndrome, wherein a male has no volition in his emissionless state.
Retrograde ejaculation occurs when semen which would be ejaculated via the urethra is redirected to the urinary bladder. Normally, the sphincter of the bladder contracts before ejaculation, inhibiting urination and preventing a reflux of semen into the bladder. The semen is forced to exit via the urethra, the path of least resistance. When the bladder sphincter does not function properly, retrograde ejaculation may occur. It can also be induced deliberately by a male as a primitive form of male birth control or as part of certain alternative medicine practices. The retrograde-ejaculated semen is excreted from the bladder during the next urination.
The seminal vesicles are a pair of convoluted tubular accessory glands that lie behind the urinary bladder of male mammals. They secrete fluid that largely composes the semen.
The ejaculatory ducts are paired structures in the male reproductive system. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and open into the urethra above the seminal colliculus. During ejaculation, semen passes through the prostate gland, enters the urethra and exits the body via the urinary meatus.
The human female reproductive system is made up of the internal and external sex organs that function in the reproduction of new offspring. The reproductive system is immature at birth and develops at puberty to be able to release matured ova from the ovaries, facilitate their fertilization, and create a protective environment for the developing fetus during pregnancy. The female reproductive tract is made of several connected internal sex organs—the vagina, uterus, and fallopian tubes—and is prone to infections. The vagina allows for sexual intercourse, and is connected to the uterus at the cervix. The uterus accommodates the embryo by developing the uterine lining.
The male reproductive system consists of a number of sex organs that play a role in the process of human reproduction. These organs are located on the outside of the body, and within the pelvis.
The human reproductive system includes the male reproductive system, which functions to produce and deposit sperm, and the female reproductive system, which functions to produce egg cells and to protect and nourish the fetus until birth. Humans have a high level of sexual differentiation. In addition to differences in nearly every reproductive organ, there are numerous differences in typical secondary sex characteristics.
Hypospermia is a condition in which a man has an unusually low ejaculate volume, less than 1.5 mL. It is the opposite of hyperspermia, which is a semen volume of more than 5.5 mL. It should not be confused with oligospermia, which means low sperm count. Normal ejaculate when a man is not drained from prior sex and is suitably aroused is around 1.5–6 mL, although this varies greatly with mood, physical condition, and sexual activity. Of this, around 1% by volume is sperm cells. The U.S.-based National Institutes of Health defines hypospermia as a semen volume lower than 2 mL on at least two semen analyses.
A semen analysis, also called seminogram or spermiogram, evaluates certain characteristics of a male's semen and the sperm contained therein. It is done to help evaluate male fertility, whether for those seeking pregnancy or verifying the success of vasectomy. Depending on the measurement method, just a few characteristics may be evaluated or many characteristics may be evaluated. Collection techniques and precise measurement method may influence results. The assay is also referred to as ejaculate analysis, human sperm assay (HSA), sperm function test, and sperm assay.
In human anatomy, the penis is an external sex organ through which males urinate and ejaculate. The main parts are the root, body, the epithelium of the penis including the shaft skin, and the foreskin covering the glans. The body of the penis is made up of three columns of tissue: two corpora cavernosa on the dorsal side and corpus spongiosum between them on the ventral side. The urethra passes through the prostate gland, where it is joined by the ejaculatory ducts, and then through the penis. The urethra goes across the corpus spongiosum and ends at the tip of the glans as the opening, the urinary meatus.
Semen, also known as seminal fluid, is a bodily fluid that contains spermatozoa. Spermatozoa are secreted by the male gonads and other sexual organs of male or hermaphroditic animals and can fertilize the female ovum. In placental mammals, semen also contains secretions from the male accessory glands and is discharged from the penis through the urethral orifice during ejaculation. In humans, seminal fluid contains several components besides spermatozoa: proteolytic and other enzymes as well as fructose are elements of seminal fluid which promote the survival of spermatozoa and provide a medium through which they can move or "swim". The fluid is adapted to be discharged deep into the vagina, so the spermatozoa can pass into the uterus and form a zygote with an egg.
The reproductive system of an organism, also known as the genital system, is the biological system made up of all the anatomical organs involved in sexual reproduction. Many non-living substances such as fluids, hormones, and pheromones are also important accessories to the reproductive system. Unlike most organ systems, the sexes of differentiated species often have significant differences. These differences allow for a combination of genetic material between two individuals, which allows for the possibility of greater genetic fitness of the offspring.
Ejaculation is the discharge of semen from the testicles through the penis and out the urethra. It is the final stage and natural objective of male sexual stimulation, and an essential component of natural conception. After forming an erection, many men emit pre-ejaculatory fluid during stimulation prior to ejaculating. Ejaculation involves involuntary contractions of the pelvic floor and is normally linked with orgasm. It is a normal part of male human sexual development.
