Fluoroacetamide

Last updated
Fluoroacetamide
Skeletal formula of fluoroacetamide Fluoracetamide structural formula V.1.svg
Skeletal formula of fluoroacetamide
Ball-and-stick model of fluoroacetamide Fluoroacetamide-3D-balls.png
Ball-and-stick model of fluoroacetamide
Names
IUPAC name
2-Fluoroacetamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.010.331 OOjs UI icon edit-ltr-progressive.svg
KEGG
PubChem CID
UNII
  • InChI=1S/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5) Yes check.svgY
    Key: FVTWJXMFYOXOKK-UHFFFAOYSA-N Yes check.svgY
  • InChI=1/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5)
    Key: FVTWJXMFYOXOKK-UHFFFAOYAA
  • C(C(=O)N)F
  • FCC(=O)N
Properties
FCH2CONH2
Molar mass 77.058 g·mol−1
AppearanceColorless crystals
Melting point 107 to 109 °C (225 to 228 °F; 380 to 382 K)
Soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Very toxic
GHS labelling:
GHS-pictogram-skull.svg
Danger
H300+H310
P262, P264, P270, P280, P301+P310+P330, P302, P350, P362, P405, P501
NFPA 704 (fire diamond)
NFPA 704.svgHealth 4: Very short exposure could cause death or major residual injury. E.g. VX gasFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability (yellow): no hazard codeSpecial hazards (white): no code
4
1
Lethal dose or concentration (LD, LC):
80 mg/kg (dermal, rat)
550 mg/m3(mouse, inhalation, dust/mist)
Safety data sheet (SDS) [1]
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Fluoroacetamide is an organic compound with the chemical formula F C H 2CO NH2. It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is very toxic. [1] It is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide. [2] May cause reproductive disorders. If swallowed or in contact with skin, it can cause serious damage and death. Can cause serious eye damage. [1]

See also

References

  1. 1 2 3 https://www.sigmaaldrich.com/US/en/sds/aldrich/128341?userType=anonymous [ bare URL ]
  2. ↑ Matsumura, F; O'Brien, RD (Oct 1963). "A COMPARATIVE STUDY OF THE MODES OF ACTION OF FLUOROACETAMIDE AND FLUOROACETATE IN THE MOUSE AND AMERICAN COCKROACH". Biochem Pharmacol. 12: 1201–5. doi:10.1016/0006-2952(63)90095-9. PMID   14074120.
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