Omoconazole

Last updated
Omoconazole
Omoconazole.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • 1-[(Z)-2-[2-(4-Chlorophenoxy)ethoxy]-2-(2,4-dichlorophenyl)-1-methylvinyl]-1H-imidazole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
Formula C13H17N2O2
Molar mass 233.291 g·mol−1
3D model (JSmol)
  • Clc3ccc(C(/OCCOc1ccc(Cl)cc1)=C(/n2ccnc2)C)c(Cl)c3
  • InChI=1S/C20H17Cl3N2O2/c1-14(25-9-8-24-13-25)20(18-7-4-16(22)12-19(18)23)27-11-10-26-17-5-2-15(21)3-6-17/h2-9,12-13H,10-11H2,1H3/b20-14- Yes check.svgY
  • Key:JMFOSJNGKJCTMJ-ZHZULCJRSA-N Yes check.svgY
   (verify)

Omoconazole is an azole antifungal drug. [1]

Omonocazole is not available in the United States and Canada. [2] In other countries, it is used to treat cutaneous candidiasis, dermatophytosis, pityriasis versicolor. [3]

Related Research Articles

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<span class="mw-page-title-main">Antifungal</span> Pharmaceutical fungicide or fungistatic used to treat and prevent mycosis

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Ketoconazole, sold under the brand name Nizoral among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Applied to the skin it is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrheic dermatitis. Taken by mouth it is a less preferred option and only recommended for severe infections when other agents cannot be used. Other uses include treatment of excessive male-patterned hair growth in women and Cushing's syndrome.

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<span class="mw-page-title-main">Isavuconazonium</span> Chemical compound

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The National Center for Advancing Translational Sciences (NCATS) was established on December 23, 2011 and is located in Bethesda, Maryland. NCATS is one of 27 institutes and centers of the U.S. National Institutes of Health (NIH), an agency of the U.S. Department of Health and Human Services. The mission of NCATS is to transform scientific discoveries into new treatments and cures for disease that can be delivered faster to patients. The budget provided to NCATS for fiscal year 2018 is $557,373,000.

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Efinaconazole, sold under the brand name Jublia among others, is a triazole antifungal medication. It is approved for use in the United States, Canada, and Japan as a 10% topical solution for the treatment of onychomycosis. Efinaconazole acts as a 14α-demethylase inhibitor.

<i>Candida auris</i> Species of fungus

Candida auris is a species of fungus that grows as yeast. It is one of the few species of the genus Candida which cause candidiasis in humans. Often, candidiasis is acquired in hospitals by patients with weakened immune systems. C. auris can cause invasive candidiasis (fungemia) in which the bloodstream, the central nervous system, and internal organs are infected. It has attracted widespread attention because of its multiple drug resistance. Treatment is also complicated because it is easily misidentified as other Candida species.

Liranaftate is a topical antifungal drug. It is used as a 2% cream used to treat tinea pedis, tinea corporis (ringworm), and tinea cruris. It was approved for use in Japan in August 2000.

References

  1. Itoyama T, Aoki Y, Hiratani T, Uchida K, Yamaguchi H (September 1993). "[In vitro antifungal activity of omoconazole nitrate, a new imidazole antimycotic]". The Japanese Journal of Antibiotics (in Japanese). 46 (9): 773–80. PMID   8254897.
  2. "NCATS Inxight: Drugs — OMOCONAZOLE". drugs.ncats.io. Retrieved 16 April 2019.
  3. "Omoconazole: Indication, Dosage, Side Effect, Precaution | MIMS Malaysia". www.mims.com. Retrieved 16 April 2019.