Chlorquinaldol

Chlorquinaldol

Names
Preferred IUPAC name 5,7-Dichloro-2-methylquinolin-8-ol
Other names Anginazol; Lacoid, Nerisone
Identifiers
CAS Number	72-80-0  Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:74500  N
ChEMBL	ChEMBL224325  Y
ChemSpider	6062  Y
ECHA InfoCard	100.000.718
KEGG	D07208  Y
PubChem CID	6301
UNII	D6VHC87LLS  Y
CompTox Dashboard (EPA)	DTXSID3048998
InChI InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3 Y Key: GPTXWRGISTZRIO-UHFFFAOYSA-N Y InChI=1/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3 Key: GPTXWRGISTZRIO-UHFFFAOYAU
SMILES Clc1c(O)c2nc(ccc2c(Cl)c1)C
Properties
Chemical formula	C10H7Cl2NO
Molar mass	228.07 g/mol
Pharmacology
ATC code	D08AH02 ( WHO ) G01AC03 ( WHO ), P01AA04 ( WHO ), R02AA11 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N  verify  (what is  YN ?) Infobox references

Chlorquinaldol is an antimicrobial agent and antiseptic. ^[1] It is a chlorinated derivative of the popular chelating agent 8-hydroxyquinoline. It is applied topically as a cream and internally as a losenge. ^[2]

It was marketed by Geigy as an intestinal antiseptic and amebicide with the trade name Siosteran.^{[ citation needed ]}

References

1. Mett H, Gyr K, Zak O, Vosbeck K (July 1984). "Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs". Antimicrob. Agents Chemother. 26 (1): 35–8. doi:10.1128/aac.26.1.35. PMC   179912 . PMID   6236746.
2. Kutscher, Bernhard (2020). "Dermatologicals ( D ), 4. Antiseptics and Disinfectants ( D 08), Anti‐Acne Preparations ( D 10), and Other Dermatological Preparations ( D 11)". Ullmann's Encyclopedia of Industrial Chemistry . Weinheim: Wiley-VCH. pp. 1–22. doi:10.1002/14356007.w08_w03. ISBN   978-3-527-30673-2.