Succinyl-CoA:(R)-benzylsuccinate CoA-transferase

Last updated
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase
Identifiers
EC no. 2.8.3.15
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + (R)-2-benzylsuccinate succinate + (R)-2-benzylsuccinyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and (R)-2-benzylsuccinate, whereas its two products are succinate and (R)-2-benzylsuccinyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase. This enzyme is also called benzylsuccinate CoA-transferase. This enzyme participates in benzoate degradation via coa ligation.

Related Research Articles

<span class="mw-page-title-main">Citric acid cycle</span> Interconnected biochemical reactions releasing energy

The citric acid cycle—also known as the Krebs cycle, Szent-Györgyi-Krebs cycle or the TCA cycle (tricarboxylic acid cycle)—is a series of biochemical reactions to release the energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins. The chemical energy released is available under the form of ATP. The Krebs cycle is used by organisms that respire (as opposed to organisms that ferment) to generate energy, either by anaerobic respiration or aerobic respiration. In addition, the cycle provides precursors of certain amino acids, as well as the reducing agent NADH, that are used in numerous other reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest components of metabolism. Even though it is branded as a 'cycle', it is not necessary for metabolites to follow only one specific route; at least three alternative segments of the citric acid cycle have been recognized.

In enzymology, a succinylglutamate-semialdehyde dehydrogenase (EC 1.2.1.71) is an enzyme that catalyzes the chemical reaction

In enzymology, a 4-hydroxybenzoyl-CoA reductase (EC 1.3.7.9) is an enzyme found in some bacteria and archaea that catalyzes the chemical reaction

In enzymology, a 2-oxoglutarate synthase (EC 1.2.7.3) is an enzyme that catalyzes the chemical reaction

In enzymology, a 4-hydroxybenzaldehyde dehydrogenase (EC 1.2.1.64) is an enzyme that catalyzes the chemical reaction

In enzymology, an ethylbenzene hydroxylase (EC 1.17.99.2) is an enzyme that catalyzes the chemical reaction

In enzymology, an acetate CoA-transferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Benzylsuccinate synthase</span>

The enzyme benzylsuccinate synthase catalyzes the chemical reaction

The enzyme cyclohexa-1,5-dienecarbonyl-CoA hydratase (EC 4.2.1.100) catalyzes the chemical reaction

The enzyme phenylacetyl-CoA hydrolase (EC 3.1.2.25) catalyzes the reaction

In enzymology, a N-succinylarginine dihydrolase (EC 3.5.3.23) is an enzyme that catalyzes the chemical reaction

In enzymology, a succinylglutamate desuccinylase (EC 3.5.1.96) is an enzyme that catalyzes the chemical reaction

In enzymology, a 3-oxoadipyl-CoA thiolase is an enzyme that catalyzes the chemical reaction

In enzymology, an arginine N-succinyltransferase (EC 2.3.1.109) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Succinylornithine transaminase</span>

In enzymology, a succinylornithine transaminase (EC 2.6.1.81) is an enzyme that catalyzes the chemical reaction

(R)-benzylsuccinyl-CoA dehydrogenase is an enzyme with systematic name (R)-benzylsuccinyl-CoA:electron transfer flavoprotein oxidoreductase. This enzyme catalyses the following chemical reaction

3-Hydroxybenzoate—CoA ligase is an enzyme with systematic name 3-hydroxybenzoate:CoA ligase (AMP-forming). This enzyme catalyses the following chemical reaction

Thauera aromatica is a species of bacteria. Its type strain is K 172T.

Azoarcus evansii is a species of bacteria. Its type strain is KB 740T.

<span class="mw-page-title-main">Coenzyme A transferases</span> Coenzyme A transferases

Coenzyme A transferases (CoA-transferases) are transferase enzymes that catalyze the transfer of a coenzyme A group from an acyl-CoA donor to a carboxylic acid acceptor. Among other roles, they are responsible for transfer of CoA groups during fermentation and metabolism of ketone bodies. These enzymes are found in all three domains of life.

References


    This page is based on this Wikipedia article
    Text is available under the CC BY-SA 4.0 license; additional terms may apply.
    Images, videos and audio are available under their respective licenses.