Tavolimab

Last updated February 26, 2019

Tavolimab
Monoclonal antibody
Type	?
Source	Chimeric/humanized hybrid (mouse/human)
Target	CD134
Clinical data
Synonyms	MEDI0562
ATC code	none
Identifiers
CAS Number	1635395-25-3
ChemSpider	none
UNII	4LU9B48U4D
Chemical and physical data
Formula	C₆₅₀₈H₁₀₀₂₆N₁₇₃₀O₂₀₃₂S₄₂
Molar mass	146.4 g/mol

Tavolimab (MEDI0562, formerly tavolixizumab) (INN ^[1]) is a chimeric/humanized monoclonal antibody designed for the treatment of cancer.

This drug is being developed by MedImmune.^[2]

References

↑ World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 115" (PDF). WHO Drug Information. 30 (2).
↑ Statement On A Nonproprietary Name Adopted By The USAN Council - Tavolimab, American Medical Association.

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Monoclonal antibodies for the immune system

Immune system ("-l(i[m])-")

Human ("-limu-")	Immunosuppression : Abrilumab Adalimumab Anifrolumab ^† Atorolimumab Avelumab Belimumab Bleselumab Brodalumab Camidanlumab tesirine Carlumab Cemiplimab Dupilumab Eldelumab Emapalumab ^† Fresolimumab Gimsilumab Golimumab Lanadelumab Lenzilumab Lerdelimumab Lirilumab Mavrilimumab Metelimumab Morolimumab Namilumab Oleclumab Oxelumab§ Pamrevlumab Placulumab Sarilumab Sifalimumab Tabalumab Tezepelumab ^† Ulocuplumab Varlilumab Immune activation: Ipilimumab Atezolizumab Durvalumab Nivolumab Pembrolizumab Tremelimumab ^† Urelumab Other: Bertilimumab Zanolimumab
Mouse ("-limo-")	Afelimomab Elsilimomab Faralimomab Gavilimomab Inolimomab Maslimomab Nerelimomab Odulimomab Telimomab aritox Vepalimomab Zolimomab aritox
Chimeric ("-lixi-")	Andecaliximab ^† Basiliximab Clenoliximab Galiximab Gomiliximab Infliximab Keliximab Lumiliximab Priliximab Teneliximab Vapaliximab
Humanized ("-lizu-")	Immunosuppressive: Aselizumab Apolizumab ^§ Benralizumab Cedelizumab Certolizumab pegol Crizanlizumab ^† Daclizumab Eculizumab Efalizumab Epratuzumab Erlizumab Etrolizumab ^† Fontolizumab Inebilizumab ^† Itolizumab Lampalizumab ^† Letolizumab Ligelizumab Lulizumab pegol Mepolizumab Mogamulizumab Natalizumab Ocrelizumab Omalizumab Ozoralizumab Pascolizumab Pateclizumab Pembrolizumab Pexelizumab Pidilizumab Plozalizumab PRO 140 ^† Quilizumab Ravulizumab ^† Reslizumab Rontalizumab Rovelizumab Ruplizumab Samalizumab Siplizumab Talizumab Teplizumab Tibulizumab Tislelizumab Tocilizumab Toralizumab Tregalizumab Vatelizumab Vedolizumab Visilizumab Vobarilizumab TGN1412 ^§ Non-immunosuppressive: Ibalizumab
Chimeric + humanized ("-lixizu-")	Otelixizumab Tavolimab
Veterinary ("-lvet-")	Gilvetmab

Interleukin ("-k(i[n])-")

Human ("-kinu-")	Brazikumab Briakinumab Canakinumab Fezakinumab Fletikumab Guselkumab Secukinumab Sirukumab Tralokinumab ^† Ustekinumab
Humanized ("-kizu-", "-kinzu-")	Anrukinzumab Clazakizumab Enokizumab Gevokizumab Ixekizumab Mirikizumab Lebrikizumab Olokizumab ^† Perakizumab Risankizumab ^† Tildrakizumab

Inflammatory lesions ("-les-")

Mouse ("-leso-")	Besilesomab Fanolesomab ^‡ Lemalesomab Sulesomab

^# WHO-EM
^‡ Withdrawn from market
Clinical trials:
- ^† Phase III
- ^§Never to phase III

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