Thymidine monophosphate

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Thymidine monophosphate
DTMP chemical structure.svg
Deoxythymidine monophosphate anion 3D spacefill.png
Names
IUPAC name
Thymidine monophosphate
Other names
5'-Thymidylic acid
Identifiers
3D model (JSmol)
AbbreviationsdTMP
3916216
ChEBI
ChEMBL
ChemSpider
PubChem CID
UNII
  • InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/p-2 X mark.svgN
    Key: GYOZYWVXFNDGLU-UHFFFAOYSA-L X mark.svgN
  • Cc1cn([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)c(=O)[nH]c1=O
Properties
C10H15N2O8P
Molar mass 322.2085 g mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Thymidine monophosphate (TMP), also known as thymidylic acid (conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (conjugate base deoxythymidylate), is a nucleotide that is used as a monomer in DNA. It is an ester of phosphoric acid with the nucleoside thymidine. dTMP consists of a phosphate group, the pentose sugar deoxyribose, and the nucleobase thymine. Unlike the other deoxyribonucleotides, thymidine monophosphate often does not contain the "deoxy" prefix in its name; nevertheless, its symbol often includes a "d" ("dTMP"). [1] Dorland’s Illustrated Medical Dictionary [2] provides an explanation of the nomenclature variation at its entry for thymidine.

As a substituent, it is called by the prefix thymidylyl-.

See also

References

  1. Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p.  244. ISBN   978-0-8412-3999-9.
  2. Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.