Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. [5] [6] The protein encoded by this gene belongs to the ETS family of transcription factors. [5]
Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. [5] [6] The protein encoded by this gene belongs to the ETS family of transcription factors. [5]
ETS2 has been shown to interact with:
Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the JUN gene. c-jun was the first oncogenic transcription factor discovered. The proto-oncogene c-Jun is the cellular homolog of the viral oncoprotein v-jun. The viral homolog v-jun was discovered in avian sarcoma virus 17 and was named for ju-nana, the Japanese word for 17. The human JUN encodes a protein that is highly similar to the viral protein, which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene.
Cyclin D1 is a protein that in humans is encoded by the CCND1 gene.
Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.
Receptor tyrosine-protein kinase erbB-4 is an enzyme that in humans is encoded by the ERBB4 gene. Alternatively spliced variants that encode different protein isoforms have been described; however, not all variants have been fully characterized.
AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage as part of the insulin signal transduction pathway.
Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene.
Transcription factor jun-B is a protein that, in humans, is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene.
TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.
LIM domain only 2, also known as LMO2, RBTNL1, RBTN2, RHOM2, LIM Domain Only Protein 2, TTG2, and T-Cell Translocation Protein 2, is a protein which in humans is encoded by the LMO2 gene.
Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene.
ERG is an oncogene. ERG is a member of the ETS family of transcription factors. The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator. Genes in the ETS family regulate embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis.
ETS translocation variant 1 is a protein that in humans is encoded by the ETV1 gene.
ETS domain-containing protein Elk-4 is a protein that in humans is encoded by the ELK4 gene.
ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene.
Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene.
ETS domain-containing protein Elk-3 is a protein that in humans is encoded by the ELK3 gene.
Fms-related tyrosine kinase 4, also known as FLT4, is a protein which in humans is encoded by the FLT4 gene.
SAP1A is one of a family of proteins that contains a unique DNA binding domain termed the ETS domain.
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