Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 26-amino-acid-long signal peptide sequence during translation. POMC is part of the central melanocortin system.
T-box transcription factor TBX1 also known as T-box protein 1 and testis-specific T-box protein is a protein that in humans is encoded by the TBX1 gene. Genes in the T-box family are transcription factors that play important roles in the formation of tissues and organs during embryonic development. To carry out these roles, proteins made by this gene family bind to specific areas of DNA called T-box binding element (TBE) to control the expression of target genes.
POU domain, class 1, transcription factor 1 , also known as POU1F1, is a transcription factor for growth hormone.
Homeobox expressed in ES cells 1, also known as homeobox protein ANF, is a homeobox protein that in humans is encoded by the HESX1 gene.
T-box transcription factor TBX21, also called T-bet is a protein that in humans is encoded by the TBX21 gene.
Homeobox protein prophet of PIT-1 is a protein that in humans is encoded by the PROP1 gene.
LIM/homeobox protein Lhx3 is a protein that in humans is encoded by the LHX3 gene.
Transcription factor SOX-3 is a protein that in humans is encoded by the SOX3 gene. This gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic brain development and in determination of cell fate. The encoded protein acts as a transcriptional activator.
Transcription factor RFX4 is a protein that in humans is encoded by the RFX4 gene.
T-box transcription factor TBX22 is a protein that in humans is encoded by the TBX22 gene.
SOX12 is a protein that in humans is encoded by the SOX12 gene. Sox12 belongs to the SoxC group of Sox family of transcription factors, together with Sox4 and Sox11. Sox12-null knockout mice appear normal, unlike Sox4 or Sox11 knockout mice. This probably comes from functional redundancy with Sox4 and Sox11. Sox12 is a weaker activator than both Sox4 and Sox11 in mouse.
LIM/homeobox protein Lhx4 is a protein that in humans is encoded by the LHX4 gene.
Homeobox protein DBX1, also known as developing brain homeobox protein 1, is a protein that in humans is encoded by the DBX1 gene. The DBX1 gene is a transcription factor gene that is pivotal in interneuron differentiation in the ventral spinal cord.
Hes family bHLH transcription factor 2 is a protein that in humans is encoded by the HES2 gene.
Mitochondrial import inner membrane translocase subunit TIM16 also known as presequence translocated-associated motor subunit PAM16, mitochondria-associated granulocyte macrophage CSF-signaling molecule, or presequence translocated-associated motor subunit PAM16 is a protein that in humans is encoded by the PAM16 gene.
Four jointed box 1 is a protein that in humans is encoded by the FJX1 gene.
T-box transcription factor TBX15 is protein that is encoded in humans by the TBX15 gene.
Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene.
Family with sequence similarity 222 member A or Aggregatin is a protein of unknown function. In humans it is encoded by the gene FAM222A. Aggregatin's cellular function is not well understood, however it has been implicated in Alzheimer's Disease.
Forkhead box protein F2 is a protein that in humans is encoded by the FOXF2 gene.
