ZNF451

ZNF451
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5D2M
Identifiers
Aliases	ZNF451 , COASTER, dJ417I1.1, zinc finger protein 451, ZATT
External IDs	OMIM: 615708 MGI: 2137896 HomoloGene: 9188 GeneCards: ZNF451
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p12.1 Start 57,086,844 bp [1] End 57,170,305 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1 B|1 12.81 cM Start 33,800,626 bp [2] End 33,853,676 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum Achilles tendon cancellous bone tibia bone marrow nipple lower lobe of lung sural nerve cerebellar vermis middle frontal gyrus Top expressed in spermatid medial ganglionic eminence secondary oocyte trigeminal ganglion cumulus cells spermatocyte primitive streak vas deferens sexually immature organism ventromedial nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SUMO ligase activity transcription corepressor activity protein binding metal ion binding nucleic acid binding transferase activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II core promoter sequence-specific DNA binding Cellular component PML body nucleus nucleoplasm histone methyltransferase complex Biological process negative regulation of transcription initiation from RNA polymerase II promoter negative regulation of histone H3-K9 acetylation regulation of transcription, DNA-templated negative regulation of transforming growth factor beta receptor signaling pathway protein sumoylation transcription, DNA-templated regulation of gene expression Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26036 98403 Ensembl ENSG00000112200 ENSMUSG00000042197 UniProt Q9Y4E5 Q8C0P7 RefSeq (mRNA) NM_001031623 NM_001257273 NM_015555 NM_001290699 NM_001290700 NM_133817 NM_001359274 NM_001359275 RefSeq (protein) NP_001026794 NP_001244202 NP_056370 NP_001277628 NP_001277629 NP_598578 NP_001346203 NP_001346204 Location (UCSC) Chr 6: 57.09 – 57.17 Mb Chr 1: 33.8 – 33.85 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 451 is a novel nuclear protein that in humans is encoded by the ZNF451 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000112200 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042197 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (February 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (1): 31–9. doi: 10.1093/dnares/5.1.31 . PMID   9628581.
6. "Entrez Gene: ZNF451 zinc finger protein 451".

Further reading

• Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O (September 1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID   7566098.
• Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (June 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID   15146197. S2CID   27764390.
• Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (July 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.

External links

• ZNF451+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.