ERF (gene)

Last updated
ERF
Identifiers
Aliases ERF , CRS4, PE-2, PE2, ETS2 repressor factor, CHYTS
External IDs OMIM: 611888 MGI: 109637 HomoloGene: 68516 GeneCards: ERF
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301035
NM_001308402
NM_001312656
NM_006494

NM_010155

RefSeq (protein)

NP_001287964
NP_001295331
NP_001299585
NP_006485

NP_034285

Location (UCSC) Chr 19: 42.25 – 42.26 Mb Chr 7: 25.24 – 25.25 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene. [5] [6] [7]

Contents

Related Research Articles

<span class="mw-page-title-main">ELK1</span> Protein-coding gene in humans

ETS Like-1 protein Elk-1 is a protein that in humans is encoded by the ELK1. Elk-1 functions as a transcription activator. It is classified as a ternary complex factor (TCF), a subclass of the ETS family, which is characterized by a common protein domain that regulates DNA binding to target sequences. Elk1 plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimer's disease, Down syndrome, breast cancer, and depression.

<span class="mw-page-title-main">HDAC4</span>

Histone deacetylase 4, also known as HDAC4, is a protein that in humans is encoded by the HDAC4 gene.

<span class="mw-page-title-main">FLI1</span> Protein-coding gene in the species Homo sapiens

Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene.

<span class="mw-page-title-main">ETS2</span> Protein-coding gene in the species Homo sapiens

Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.

<span class="mw-page-title-main">ETV4</span> Protein-coding gene in the species Homo sapiens

ETS translocation variant 4 (ETV4), also known as polyoma enhancer activator 3 (PEA3), is a member of the PEA3 subfamily of Ets transcription factors.

<span class="mw-page-title-main">NKX3-1</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Nkx-3.1, also known as NKX3-1, NKX3, BAPX2, NKX3A and NKX3.1 is a protein that in humans is encoded by the NKX3-1 gene located on chromosome 8p. NKX3-1 is a prostatic tumor suppressor gene.

<span class="mw-page-title-main">GABPA</span> Protein-coding gene in the species Homo sapiens

GA-binding protein alpha chain is a protein that in humans is encoded by the GABPA gene.

<span class="mw-page-title-main">ZEB1</span> Protein-coding gene in the species Homo sapiens

Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene.

<span class="mw-page-title-main">RDBP</span> Protein

Negative elongation factor E is a protein that in humans is encoded by the RDBP gene.

<span class="mw-page-title-main">RING1</span> Protein-coding gene in the species Homo sapiens

E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene.

<span class="mw-page-title-main">DR1 (gene)</span> Protein-coding gene in the species Homo sapiens

Protein Dr1 is a protein that in humans is encoded by the DR1 gene.

<span class="mw-page-title-main">MXD1</span> Protein-coding gene in the species Homo sapiens

MAD protein is a protein that in humans is encoded by the MXD1 gene.

<i>NFIC</i> (gene) Protein-coding gene in the species Homo sapiens

Nuclear factor 1 C-type is a protein that in humans is encoded by the NFIC gene.

<span class="mw-page-title-main">ELK3</span> Protein-coding gene in humans

ETS domain-containing protein Elk-3 is a protein that in humans is encoded by the ELK3 gene.

<span class="mw-page-title-main">BCLAF1</span> Protein-coding gene in the species Homo sapiens

Bcl-2-associated transcription factor 1 is a Bcl-2 family protein in humans that is encoded by the BCLAF1 gene.

<i>EHF</i> (gene) Protein-coding gene in the species Homo sapiens

ETS homologous factor is a protein that in humans is encoded by the EHF gene. This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be associated with asthma susceptibility. This protein may be involved in epithelial differentiation and carcinogenesis.

<span class="mw-page-title-main">LMX1A</span> Protein-coding gene in the species Homo sapiens

LIM homeobox transcription factor 1, alpha, also known as LMX1A, is a protein which in humans is encoded by the LMX1A gene.

<span class="mw-page-title-main">TFAP4</span> Protein-coding gene in the species Homo sapiens

Transcription factor AP-4 , also known as TFAP4, is a protein which in humans is encoded by the TFAP4 gene.

<span class="mw-page-title-main">ELF1</span> Protein-coding gene in the species Homo sapiens

E74-like factor 1 is a protein that in humans is encoded by the ELF1 gene.

<span class="mw-page-title-main">Ets variant 3</span> Protein-coding gene in the species Homo sapiens

Ets variant 3 is a protein that in humans is encoded by the ETV3 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000105722 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040857 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ (October 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". The EMBO Journal. 14 (19): 4781–93. doi:10.1002/j.1460-2075.1995.tb00160.x. PMC   394576 . PMID   7588608.
  6. de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (June 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID   9192842.
  7. "Entrez Gene: ERF Ets2 repressor factor".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.