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Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella typhi. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over several days. This is commonly accompanied by weakness, abdominal pain, constipation, headaches, and mild vomiting. Some people develop a skin rash with rose colored spots. In severe cases, people may experience confusion. Without treatment, symptoms may last weeks or months. Diarrhea may be severe, but is uncommon. Other people may carry it without being affected, but are still contagious. Typhoid fever is a type of enteric fever, along with paratyphoid fever. Salmonella enterica Typhi is believed to infect and replicate only within humans.
Mary Mallon, commonly known as Typhoid Mary, was an Irish-born American cook who is believed to have infected between 51 and 122 people with typhoid fever. The infections caused three confirmed deaths, with unconfirmed estimates of as many as 50. She was the first person in the United States identified as an asymptomatic carrier of the pathogenic bacteria Salmonella typhi. She was forcibly quarantined twice by authorities, the second time for the remainder of her life because she persisted in working as a cook and thereby exposed others to the disease. Mallon died after a total of nearly 30 years quarantined. Her popular nickname has since become a term for persons who spread disease or other misfortune.
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Salmonellosis is a symptomatic infection caused by bacteria of the Salmonella type. It is the most common disease to be known as food poisoning, these are defined as diseases, usually either infectious or toxic in nature, caused by agents that enter the body through the ingestion of food. In humans, the most common symptoms are diarrhea, fever, abdominal cramps, and vomiting. Symptoms typically occur between 12 hours and 36 hours after exposure, and last from two to seven days. Occasionally more significant disease can result in dehydration. The old, young, and others with a weakened immune system are more likely to develop severe disease. Specific types of Salmonella can result in typhoid fever or paratyphoid fever. Typhoid fever and paratyphoid fever are specific types of salmonellosis, known collectively as enteric fever, and are, respectively, caused by salmonella typhi and paratyphi bacteria, which are only found in humans. Most commonly, salmonellosis cases arise from salmonella bacteria from animals, and chicken is a major source for these infections.
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Typhus, also known as typhus fever, is a group of infectious diseases that include epidemic typhus, scrub typhus, and murine typhus. Common symptoms include fever, headache, and a rash. Typically these begin one to two weeks after exposure.
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In 1964, there was an outbreak of typhoid in the city of Aberdeen, Scotland. The first two cases were identified on 20 May 1964; eventually over 400 cases were diagnosed and the patients were quarantined at the City Hospital in Urquhart Road, Woodend Hospital in Eday Road, and Tor-na-Dee Hospital in Milltimber which was used as an overflow hospital for typhoid cases. There were three deaths connected with the outbreak. Dr Ian MacQueen, the Medical Officer of Health for Aberdeen, became well known in the media for his twice-daily briefings.
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In 2000, typhoid fever caused an estimated 21.7 million illnesses and 217,000 deaths. It occurs most often in children and young adults between 5 and 19 years old. In 2013, it resulted in about 161,000 deaths – down from 181,000 in 1990. Infants, children, and adolescents in south-central and Southeast Asia experience the greatest burden of illness. Outbreaks of typhoid fever are also frequently reported from sub-Saharan Africa and countries in Southeast Asia. In the United States, about 400 cases occur each year, and 75% of these are acquired while traveling internationally.
The Croydon typhoid outbreak of 1937, also known as the Croydon epidemic of typhoid fever, was an outbreak of typhoid fever in Croydon, Surrey, now part of London, in 1937. It resulted in 341 cases of typhoid, and it caused considerable local discontent leading to a media campaign and a public inquiry.
City Hospital is a health facility on Urquhart Road in Aberdeen, Scotland. It is managed by NHS Grampian.
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References
- ↑ Cotes-Preedy, D. (17 April 1937). "The Bournemouth Typhoid Outbreak". British Medical Journal. 1 (3980): 825–826. doi:10.1136/bmj.1.3980.825. ISSN 0007-1447. PMC 2088641 . PMID 20780616.
- ↑ "The Bournemouth Outbreak of Typhoid Fever". Nature. 140 (3534): 145–146. 1 July 1937. doi: 10.1038/140145d0 . ISSN 1476-4687. S2CID 34597295.
- ↑ "Typhoid outbreak, Bournemouth. (Hansard, 22 July 1937)". api.parliament.uk.
- ↑ Smith, David F.; Diack, H. Lesley; Pennington, T. Hugh; Pennington, Thomas Hugh; Russell, Elizabeth M. (2005). Food Poisoning, Policy, and Politics: Corned Beef and Typhoid in Britain in the 1960s. Boydell Press. ISBN 1-84383-138-4.
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