Glutamate receptor, ionotropic kainate 5 is a protein that in humans is encoded by the GRIK5 gene. [5] [6]
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. [6]
GRIK5 has been shown to interact with DLG4 [7] [8] and GRIK2. [9] [10]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.