P2X purinoceptor 6 is a protein that in humans is encoded by the P2RX6 gene. [5] [6] [7] [8]
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. [8]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.