Amflutizole

Amflutizole
Clinical data
ATC code	none;
Identifiers
	IUPAC name 4-Amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid;
CAS Number	82114-19-0 ;
PubChem CID	54833 ;
ChemSpider	49508 ;
UNII	83N680M457 ;
KEGG	D02896 ;
ChEMBL	ChEMBL2106558 ;
CompTox Dashboard (EPA)	DTXSID00868642 ;
Chemical and physical data
Formula	C11H7F3N2O2S
Molar mass	288.24 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES FC(F)(F)c1cccc(c1)c2nsc(c2N)C(=O)O;
	InChI InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18) ; Key:KVMCEGAWQYTFKC-UHFFFAOYSA-N ;
	(verify)

Last updated December 30, 2025

Amflutizole is a xanthine oxidase inhibitor ^[1] used for the treatment of gout.

References

↑ O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994). "The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex". Neuropharmacology. 33 (10): 1197–201. doi:10.1016/S0028-3908(05)80010-3. PMID 7862255. S2CID 37262919.

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[1] O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994). "The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex". Neuropharmacology. 33 (10): 1197–201. doi:10.1016/S0028-3908(05)80010-3. PMID 7862255. S2CID 37262919.

[1]

Clinical data

ATC code	none
Identifiers
IUPAC name 4-Amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid
CAS Number	82114-19-0 ^Y
PubChem CID	54833
ChemSpider	49508 ^Y
UNII	83N680M457
KEGG	D02896 ^Y
ChEMBL	ChEMBL2106558
CompTox Dashboard (EPA)	DTXSID00868642
Chemical and physical data
Formula	C₁₁H₇F₃N₂O₂S
Molar mass	288.24 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES FC(F)(F)c1cccc(c1)c2nsc(c2N)C(=O)O
InChI InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18)^Y Key:KVMCEGAWQYTFKC-UHFFFAOYSA-N^Y
(verify)