P2RX5

Last updated
P2RX5
Identifiers
Aliases P2RX5 , LRH-1, P2X5, P2X5R, purinergic receptor P2X 5
External IDs OMIM: 602836; MGI: 2137026; HomoloGene: 1924; GeneCards: P2RX5; OMA:P2RX5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_175081
NM_001204519
NM_001204520
NM_002561
NM_175080

Contents

NM_033321
NM_001376982
NM_001376983

RefSeq (protein)

NP_001191448
NP_001191449
NP_002552
NP_778255

n/a

Location (UCSC) Chr 17: 3.67 – 3.7 Mb Chr 11: 73.05 – 73.06 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

P2X purinoceptor 5 is a protein in humans that is encoded by the P2RX5 gene. [5] [6]

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Four transcript variants encoding distinct isoforms have been identified for this gene. [6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000083454 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005950 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Le KT, Paquet M, Nouel D, Babinski K, Seguela P (Jan 1998). "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system". FEBS Lett. 418 (1–2): 195–9. doi:10.1016/S0014-5793(97)01380-X. PMID   9414125. S2CID   42070561.
  6. 1 2 "Entrez Gene: P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.