ATP-binding cassette sub-family A member 12 also known as ATP-binding cassette transporter 12 is a protein that in humans is encoded by the ABCA12 gene.
Purinergic receptors, also known as purinoceptors, are a family of plasma membrane molecules that are found in almost all mammalian tissues. Within the field of purinergic signalling, these receptors have been implicated in learning and memory, locomotor and feeding behavior, and sleep. More specifically, they are involved in several cellular functions, including proliferation and migration of neural stem cells, vascular reactivity, apoptosis and cytokine secretion. These functions have not been well characterized and the effect of the extracellular microenvironment on their function is also poorly understood.
The P2X receptors, also ATP-gated P2X receptor cation channel family, is a protein family that consists of cation-permeable ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). They belong to a larger family of receptors known as the ENaC/P2X superfamily. ENaC and P2X receptors have similar 3-D structures and are homologous. P2X receptors are present in a diverse array of organisms including humans, mouse, rat, rabbit, chicken, zebrafish, bullfrog, fluke, and amoeba.
P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
P2X purinoceptor 1, also ATP receptor, is a protein that in humans is encoded by the P2RX1 gene.
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.
P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.
P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.
Lysophosphatidic acid receptor 6, also known as LPA6, P2RY5 and GPR87, is a protein that in humans is encoded by the LPAR6 gene. LPA6 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.
P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.
P2X purinoceptor 4 is a protein that in humans is encoded by the P2RX4 gene. P2X purinoceptor 4 is a member of the P2X receptor family. P2X receptors are trimeric protein complexes that can be homomeric or heteromeric. These receptors are ligand-gated cation channels that open in response to ATP binding. Each receptor subtype, determined by the subunit composition, varies in its affinity to ATP and desensitization kinetics.
P2X purinoceptor 2 is a protein that in humans is encoded by the P2RX2 gene.
P2X purinoceptor 3 is a protein that in humans is encoded by the P2RX3 gene.
Immunoglobulin superfamily member 8 is a protein that in humans is encoded by the IGSF8 gene. IGSF8 has also been designated as CD316.
Nuclear receptor-binding factor 2 is a protein that in humans is encoded by the NRBF2 gene.
P2X purinoceptor 6 is a protein that in humans is encoded by the P2RX6 gene.
