Indobufen

Indobufen
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B01AC10 ( WHO );
Identifiers
	IUPAC name 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid;
CAS Number	63610-08-2 ;
PubChem CID	107641 ;
ChemSpider	96823 ;
UNII	6T9949G4LZ ;
KEGG	D07141 ;
ChEMBL	ChEMBL1765292 ;
CompTox Dashboard (EPA)	DTXSID7057789 ;
ECHA InfoCard	100.058.496
Chemical and physical data
Formula	C18H17NO3
Molar mass	295.338 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES O=C(O)C(c1ccc(cc1)N3C(=O)c2ccccc2C3)CC;
	InChI InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22) ; Key:AYDXAULLCROVIT-UHFFFAOYSA-N ;
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Last updated January 11, 2026

Indobufen is a platelet aggregation inhibitor.^[1] It acts as a reversible cyclooxygenase inhibitor.^[2]

References

↑ The Merck Index (12th ed.). p. 4991.
↑ Eligini S, Violi F, Banfi C, Barbieri SS, Brambilla M, Saliola M, et al. (January 2006). "Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism". Cardiovascular Research. 69 (1): 218–26. doi: 10.1016/j.cardiores.2005.07.013 . PMID 16154551.

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[1] The Merck Index (12th ed.). p. 4991.

[2] Eligini S, Violi F, Banfi C, Barbieri SS, Brambilla M, Saliola M, et al. (January 2006). "Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism". Cardiovascular Research. 69 (1): 218–26. doi: 10.1016/j.cardiores.2005.07.013 . PMID 16154551.

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