Aloxiprin

Aloxiprin

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B01AC15 ( WHO ) N02BA02 ( WHO )
Legal status
Legal status	AU: S2 (Pharmacy medicine) [1]
Identifiers
IUPAC name aluminium 2-acetyloxybenzoate hydroxide
CAS Number	9014-67-9
PubChem CID	71586929
ChemSpider	32698107
UNII	6QT214X4XU
KEGG	D07421
CompTox Dashboard (EPA)	DTXSID60238044
Chemical and physical data
Formula	C9H8Al2O7
Molar mass	282.119 g·mol−1
3D model (JSmol)	Interactive image Interactive image
SMILES CC(=O)OC1=CC=CC=C1C(=O)O.[O-2].[O-2].[O-2].[Al+3].[Al+3] CC(=O)Oc0ccccc0C(=O)O[Al](O)OC(=O)c1ccccc1OC(=O)C
InChI InChI=1S/C9H8O4.2Al.3O/c1-6(10)13-8-5-3-2-4-7(8)9(11)12;;;;;/h2-5H,1H3,(H,11,12);;;;;/q;2*+3;3*-2 Key:MXCPYJZDGPQDRA-UHFFFAOYSA-N

Aloxiprin (or aluminium acetylsalicylate) is a medication used for the treatment of pain and inflammation associated with muscular skeletal and joint disorders. It is used for its properties as an anti-inflammatory, antipyretic and analgesic drug. ^[2] It is a chemical compound of aluminium hydroxide and aspirin. ^{[3] [4]}

Alternative names and combinations

• Palaprin Forte ^[5]
• Askit Powders - A powder combination of aspirin, aloxiprin and caffeine. ^[6]

Contraindications

• People with allergies to salicylates.
• People with gastrointestinal ulcers.
• People with liver or kidney damage.
• Pregnant women in the third trimester.
• Women who are breastfeeding.
• Use with other salicylates.
• Use with Nonsteroidal anti-inflammatory drugs (NSAIDs).

References

1. "Therapeutic Goods (Poisons Standard— June 2025) Instrument 2025" (pdf). Therapeutic Goods Administration (TGA). May 2025. Retrieved 31 August 2025.
2. MIMS. "Aloxiprin". MIMS. Retrieved 16 April 2011.
3. Encarta. "Aloxiprin". Encarta. Retrieved 16 April 2011.^{[ permanent dead link ]}
4. CUMMINGS AJ, MARTIN BK, WIGGINS LF (1963). "In vitro and in vivo properties of aloxiprin: a new aluminium derivative of acetylsalicylic acid". J. Pharm. Pharmacol. 15: 56–62. doi:10.1111/j.2042-7158.1963.tb12743.x. PMID   14024235. S2CID   33366977.
5. Geller J (1968). "A comparative trial of aloxiprin ('Palaprin Forte') and phenylbutazone ('Butazolidin')". The British Journal of Clinical Practice. 22 (9): 392–4. PMID   4876729.
6. Net Doctor UK. "Askit Powders". Treatments for joint, muscle and bone conditions. Retrieved 16 April 2011.