Ibuproxam

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Ibuproxam
Ibuproxam.png
Clinical data
ATC code
Identifiers
  • N-Hydroxy-2-[4-(2-methylpropyl)phenyl]propanamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
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ECHA InfoCard 100.053.331 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C13H19NO2
Molar mass 221.300 g·mol−1
3D model (JSmol)
Melting point 119–121 °C (246–250 °F)
  • O=C(NO)C(c1ccc(cc1)CC(C)C)C
  • InChI=1S/C13H19NO2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(15)14-16/h4-7,9-10,16H,8H2,1-3H3,(H,14,15) X mark.svgN
  • Key:BYPIURIATSUHDW-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Ibuproxam is a nonsteroidal anti-inflammatory drug (NSAID).It is the hydroxamic acid of ibuprofen to which it is hydrolyzed in the blood. It was found, that ibuproxam is considerably less damaging to the gastrointestinal tract than is ibuprofen. The analgesic and the antipyretic activities are consistent. [1]

Related Research Articles

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Ibuprofen/famotidine, sold under the brand name Duexis, is a fixed-dose combination medication used for the treatment of rheumatoid arthritis and osteoarthritis. It contains ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) and famotidine, a histamine H2-receptor antagonist.

<span class="mw-page-title-main">Gadolinium(III) hydroxide</span> Chemical compound

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References

  1. Orzalesi G, Selleri R, Caldini O, Volpato I, Innocenti F, Colome J, Sacristan A, Varez G (1977). "Ibuproxam and ibuprofen. A pharmacological comparison". Arzneimittel-Forschung. 27 (5): 1006–12. PMID   577862.