Alclofenac

Last updated
Alclofenac
Alclofenac.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • 2-(3-chloro-4-prop-2-enoxyphenyl)acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.040.709 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C11H11ClO3
Molar mass 226.66 g·mol−1
3D model (JSmol)
  • Clc1cc(ccc1OC\C=C)CC(=O)O
  • InChI=1S/C11H11ClO3/c1-2-5-15-10-4-3-8(6-9(10)12)7-11(13)14/h2-4,6H,1,5,7H2,(H,13,14) Yes check.svgY
  • Key:ARHWPKZXBHOEEE-UHFFFAOYSA-N Yes check.svgY
   (verify)

Alclofenac is a nonsteroidal anti-inflammatory drug (NSAID).

Synthesis

Alclofenac synthesis pathway Alclofenac synthesis.svg
Alclofenac synthesis pathway

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References

  1. ↑ Gaviraghi G, Banfi S, Cornelli U, Pinza M, Pifferi G (April 1977). "Synthesis and antiinflammatory activity of 3-chloro-4-cyclopropylmethoxyphenylacetic acid and its alpha-methyl homologue". Il Farmaco; Edizione Scientifica. 32 (4): 286–95. PMID   862882.
  2. ↑ CA 831040,Gillet C, Buu HN, Lambelin G,"Substituted Phenylacetic Acids and Processes of Preparation Thereof",published 30 December 1969, assigned to Madan Ag
  3. ↑ US 3824277,Gillet C, Buu HN, Lambelin G,"4-Allyloxy-3-chloro-phenyl-acetic acid",published 16 July 1974, assigned to Madan Ag


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